128 completed, 24 unknown, 23 recruiting, 13 terminated. 42 Phase 3, 38 Not applicable, 33 Phase 2, 17 Phase 4, 15 Phase 1.
Follow Lung Diseases, Fungal: new trials by email Literature Review of Lung Diseases, Fungal trials Research Report on Lung Diseases, Fungal
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Platform Trial for Salvage Consolidation Therapy in Dimorphic Fungi Oteseconazole - Coccidioidomycosis, Blastomycosis | Phase 2 | Not yet recruiting | University of Minnesota | 30 | 2026-12-01 | 2026-09-04 |
| Real-World Effectiveness of Depemokimab in Allergic Bronchopulmonary Aspergillosis With Severe Eosinophilic Asthma Depemokimab - Allergic Bronchopulmonary Aspergillosis, ABPA | Not applicable | Not yet recruiting | Qianfoshan Hospital | 10 | 2026-11-01 | 2026-09-24 |
| Real-World Effectiveness of Tezepelumab in Allergic Bronchopulmonary Aspergillosis Tezepelumab - Allergic Bronchopulmonary Aspergillosis, Severe Asthma | Not applicable | Not yet recruiting | Qianfoshan Hospital | 10 | 2026-09-01 | 2026-08-11 |
| Low- vs Standard-Dose TMP-SMX for Prevention of Pneumocystis Pneumonia After Kidney Transplantation Trimethoprim-Sulfamethoxazole (TMP-SMX) - Pneumocystis Jirovecii Pneumonia, Kidney Transplantation | Phase 4 | Not yet recruiting | Anhui Provincial Hospital | 1084 | 2026-06-01 | 2026-06-01 |
| Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives) Clindamycin + primaquine, Pentamidine, Atovaquone - Pneumocystis, Pneumocystis Infection | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-03-01 | 2026-01-21 |
| How Long Should we Give Steroids for Patients With Severe PCP Systemic corticosteroids - Pneumocystis Pneumonia, Pneumocystis | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-01-30 | 2026-01-09 |
| A Study of the Efficacy and Safety of Bronchoscopic Airway Clearance and Amphotericin B Spraying in Patients With ABPA The patients were treated with bronchoscopic airway clearance and amphotericin B spraying - ABPA, Allergic Bronchopulmonary Aspergillosis | Recruiting | Qianfoshan Hospital | 44 | 2026-01-10 | 2026-01-23 | |
| CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia Caspofungin Acetate 50 MG, Physiologic saline - Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection | Phase 1 / Phase 2 | Recruiting | University Hospital, Tours | 100 | 2025-12-02 | 2026-10-09 |
| Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia trimethoprim-sulfamethoxazole - Pneumocystis, Pneumocystis Pneumonia | Phase 3 | Recruiting | Todd C. Lee MD MPH FIDSA | 416 | 2025-11-28 | 2026-02-20 |
| Derivation and Validation of the Fungal Pneumonia Assessment and Likelihood Predictor Score FUNGAL-P Score Assessment - Pneumonia, Fungal Pneumonia | Recruiting | Azienda Ospedaliero-Universitaria Careggi | 400 | 2025-11-13 | 2026-07-02 | |
| Influenza A-associated Pulmonary Aspergillosis in Patients Admitted to the Intensive Care Unit in China IPA and non-IPA groups - ICU, Invasive Pulmonary Aspergillosis | Completed | Jianfeng Xie | 542 | 2025-11-01 | 2026-01-09 | |
| Corticosteroids for PJP in Non-HIV Immunocompromised Adults Saline (0.9%, sterile, for infusion), Low Dose Corticosteroids, Moderate dose corticosteroids - Pneumocystis Jiroveci Pneumonia | Phase 3 | Not yet recruiting | Qingyuan Zhan | 240 | 2025-09-08 | 2025-09-09 |
| Pneumocystis Jirovecii Genotyping Pneumocystis Pneumonia | Not yet recruiting | Nottingham University Hospitals NHS Trust | 70 | 2025-09-01 | 2025-06-27 | |
| Real-World Effectiveness of Benralizumab in Allergic Bronchopulmonary Aspergillosis Fasenra - Allergic Bronchopulmonary Aspergillosis, Severe Asthma | Recruiting | Qianfoshan Hospital | 20 | 2025-09-01 | 2026-04-21 | |
| Liver Cirrhosis Patients With Invasive Pulmonary Aspergillosis: in Depth Understanding Clinical Host Risk Factors Liver Cirrhosis, Viral Pneumonia | Active not recruiting | Universitaire Ziekenhuizen KU Leuven | 450 | 2025-08-01 | 2026-03-04 | |
| Immune Status and Disease Control of Inflammatory Airway Diseases Airway Inflammation, Chronic Obstructive Pulmonary Disease (COPD) | Recruiting | First Affiliated Hospital of Ningbo University | 200 | 2025-08-01 | 2026-03-25 | |
| Optimizing the Diagnosis of Pneumocystis in Immunocompromised Patients Biological sampling - Pneumocystis, Immunocompromised Patients | Recruiting | Assistance Publique - Hôpitaux de Paris | 240 | 2025-07-08 | 2026-04-23 | |
| Fungal Status and Prognosis in ABPA ABPA, Allergic Bronchopulmonary Aspergillosis | Recruiting | Qianfoshan Hospital | 114 | 2025-07-01 | 2026-07-08 | |
| Pathogenesis and Inflammatory Phenotype of Allergic Bronchopulmonary Aspergillosis Allergic Bronchopulmonary Aspergillosis (ABPA) | Recruiting | Qianfoshan Hospital | 140 | 2025-05-10 | 2025-07-04 | |
| iMagIng pulmonaRy Aspergillosis Using Gallium-68-dEferoxamine Radiopharmaceutical: gallium-68-deferoxamine ([68Ga]Ga-DFO-B) - Pulmonary Aspergillosis, Chronic Pulmonary Aspergillosis | Phase 2 | Completed | Radboud University Medical Center | 10 | 2025-05-01 | 2026-08-18 |
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Pneumonia, Pneumocystis (107) · HIV Infections (60) · Acquired Immunodeficiency Syndrome (56) · Invasive Pulmonary Aspergillosis (43) · Aspergillosis, Allergic Bronchopulmonary (42) · AIDS-Related Opportunistic Infections (30) · Mycoses (18) · AIDS-Related Complex (17) · Pulmonary Aspergillosis (13) · Aspergillosis (12) · Asthma (12) · Pneumonia (11) · Blastomycosis (10) · Respiratory Aspiration (9)
Respiratory Tract Diseases (208) · Bacterial Infections and Mycoses (207) · Lung Diseases (207) · Infections (203) · Mycoses (190) · Respiratory Tract Infections (171) · Immune System Diseases (111) · Pneumonia (101) · Pneumocystis Infections (99) · Aspergillosis (81) · Pulmonary Aspergillosis (76) · RNA Virus Infections (72) · Virus Diseases (72) · Urogenital Diseases (65)
Trimethoprim, Sulfamethoxazole Drug Combination (23) · Pentamidine (22) · Leucovorin (13) · trimetrexate glucuronate (12) · Itraconazole (11) · Atovaquone (10) · Dapsone (10) · Voriconazole (9) · Zidovudine (7) · Caspofungin (6) · Amphotericin B (5) · Methylprednisolone (5) · Trimethoprim (5) · Blood Specimen Collection (4) · Clindamycin (4)
National Institute of Allergy and Infectious Diseases (NIAID) (37) · Post Graduate Institute of Medical Education and Research, Chandigarh (9) · Qianfoshan Hospital (9) · Fisons (5) · U.S. Bioscience (5) · University of Pittsburgh (5) · Glaxo Wellcome (4) · TFF Pharmaceuticals, Inc. (3) · Universitaire Ziekenhuizen KU Leuven (3) · Asan Medical Center (2) · Assistance Publique - Hôpitaux de Paris (2) · Central Hospital, Nancy, France (2) · GlaxoSmithKline (2) · Jacobus Pharmaceutical (2) · LyphoMed (2)
United States (85) · France (32) · China (30) · Belgium (16) · Germany (13) · United Kingdom (13) · Canada (12) · India (12) · Netherlands (9) · Italy (7) · Puerto Rico (7) · Spain (6) · Australia (5) · Israel (5) · South Africa (5)
Feinberg J (5) · Alison Morris-Gimbel, MD (2) · B Montgomery (2) · Black JR (2) · Dale Christensen, PhD (2) · El-Sadr W (2) · Emily G McDonald, MD MSc (2) · Fischl M (2) · Frame P (2) · Jay K Kolls, MD (2) · Joost Wauters, MD, PhD (2) · Luskin-Hawk R (2) · Masur H (2) · Ptachcinski R (2)
PMID 33027187, PMID 41151592, PMID 15504856, PMID 16304338, PMID 18046534, PMID 18230259, PMID 20607114, PMID 20946413, PMID 21729932, PMID 21732834, PMID 21854805, PMID 22548840, PMID 23359515, PMID 23940606, PMID 25203869, PMID 25376267, PMID 25603113, PMID 25927915, PMID 26050015, PMID 26302738, PMID 26585431, PMID 26872154, PMID 26935726, PMID 27011794, PMID 28530849, PMID 29313714, PMID 29331473, PMID 29514207, PMID 30049743, PMID 30561849, PMID 30776290, PMID 31548210, PMID 31633150, PMID 32194238, PMID 32391667, PMID 32407157, PMID 32457106, PMID 32479781, PMID 32653726, PMID 32671131, PMID 33005696, PMID 33213011, PMID 33293212, PMID 33438477, PMID 33538349, PMID 33549194, PMID 33586013, PMID 33744933, PMID 34349985, PMID 34682270
2017 (4), 2019 (3), 2016 (2), 2023 (2), P50HL084932 (2), 2018 (1), R01AI139032 (1), R01HL083461 (1), R01HL090339 (1), U01AI068632 (1)