8 completed, 4 recruiting, 1 active not recruiting, 1 suspended. 15 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Completed 8, Recruiting 4, Active not recruiting 1, Suspended 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
Follow Pediatric Obesity: new trials by email Literature Review of Pediatric Obesity trials Research Report on Pediatric Obesity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth Semaglutide 2.4 mg - Pediatric Obesity, Metabolic and Bariatric Surgery | Phase 3 | Recruiting | Children's Hospital Los Angeles | 150 | 2026-09-01 | 2026-09-02 |
| Food-Body-Mind Intervention (16 Weeks) Food-Body-Mind - Mental Health Wellness, Emotional Problem | Phase 2 / Phase 3 | Recruiting | Michigan State University | 800 | 2024-08-14 | 2026-10-05 |
| Effect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study) Essential Amino Acid Supplement by Amino Co, Placebo - Hepatic Steatosis, NAFLD | Phase 3 | Completed | University of Colorado, Denver | 31 | 2024-06-18 | 2026-08-31 |
| Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents Monthly bolus of cholecalciferol per os, Daily dose of cholecalciferol per os - Obesity, Childhood | Phase 3 | Recruiting | Hospices Civils de Lyon | 68 | 2023-12-04 | 2025-06-13 |
| Eat My ABCs Project Eat My ABCs - Nutrition, Healthy, Obesity, Childhood | Phase 2 / Phase 3 | Completed | Michigan State University | 202 | 2023-01-01 | 2024-06-07 |
| Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity Setmelanotide - Bardet-Biedl Syndrome, POMC Deficiency Obesity | Phase 3 | Completed | Rhythm Pharmaceuticals, Inc. | 12 | 2022-03-08 | 2024-11-27 |
| Pharmacotherapy for Pediatric Obesity: A Phentermine Clinical Trial Lifestyle Management - Obesity, Childhood | Phase 3 | Withdrawn | University of Minnesota | 2022-01-01 | 2021-08-05 | |
| Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance Metformin 850 mg oral tablet bid, Supplemental fiber mixture (35 g total) composed of 6g of Oligofructose + 12g of resistant maltodextrin + 12g of acacia gum + 5g of PGX. - Obesity, Childhood, Insulin Resistance | Phase 3 | Recruiting | University of Alberta | 90 | 2021-10-22 | 2026-10-23 |
| Brain Activation and Satiety in Children 2 Family Based Behavioral Treatment, Exenatide 2 mg [Bydureon], Placebo - Childhood Obesity | Phase 3 | Active not recruiting | Seattle Children's Hospital | 63 | 2021-01-28 | 2026-01-05 |
| Treating PCOS With Semaglutide vs Active Lifestyle Intervention Semaglutide 3mg and 7mg [Rybelsus], Weight loss diet - PCOS, Adolescent Obesity | Phase 2 / Phase 3 | Completed | University of Colorado, Denver | 60 | 2019-05-03 | 2025-11-25 |
| Acetaminophen Dosing in Obese Adolescents Tylenol - Obesity, Childhood | Phase 3 | Suspended | Children's National Research Institute | 6 | 2016-08-01 | 2024-08-22 |
| The Optimising Family Engagement in HENRY (OFTEN) Study Optimisation + HENRY, HENRY as standard - Childhood Obesity | Phase 3 | Completed | University of Leeds | 126 | 2015-10-01 | 2022-03-25 |
| Obalon in Children With Severe Obesity Swallowable Obalon® Gastric Balloon - Severe Pediatric Obesity (BMI > 97° pc -According to Centers for Disease Control and Prevention BMI Charts-), Altered Liver Function Tests | Phase 3 | Completed | Bambino Gesù Hospital and Research Institute | 10 | 2014-01-01 | 2015-07-22 |
| Effect of Mindful Eating on Body Mass Index in Obese Adolescents Mindful Eating, Standard dietary counselling - Adolescent Obesity | Phase 3 | Completed | Mayo Clinic | 21 | 2012-12-01 | 2014-01-22 |
| Propofol in Obese Children Propofol - Pharmacodynamics, Obesity | Phase 3 | Completed | Baylor College of Medicine | 80 | 2008-04-01 | 2020-12-21 |
Obesity (6) · Insulin Resistance (2) · Non-alcoholic Fatty Liver Disease (2) · Bardet-Biedl Syndrome (1) · Fatty Liver (1) · Obesity, Morbid (1) · Proopiomelanocortin Deficiency (1) · Social Skills (1) · Vitamin D Deficiency (1)
Body Weight (15) · Nutrition Disorders (15) · Nutritional and Metabolic Diseases (15) · Overnutrition (15) · Overweight (15) · Pathological Conditions, Signs and Symptoms (15) · Signs and Symptoms (15) · Obesity (9) · Digestive System Diseases (2) · Glucose Metabolism Disorders (2) · Hyperinsulinism (2) · Liver Diseases (2) · Metabolic Diseases (2) · Abnormalities, Multiple (1) · Avitaminosis (1)
semaglutide (2) · Acetaminophen (1) · Diet, Reducing (1) · Exenatide (1) · Gum Arabic (1) · Metformin (1) · Propofol (1) · oligofructose (1) · setmelanotide (1)
Michigan State University (2) · University of Colorado, Denver (2) · Bambino Gesù Hospital and Research Institute (1) · Baylor College of Medicine (1) · Children's Hospital Los Angeles (1) · Children's National Research Institute (1) · Hospices Civils de Lyon (1) · Mayo Clinic (1) · Rhythm Pharmaceuticals, Inc. (1) · Seattle Children's Hospital (1) · University of Alberta (1) · University of Leeds (1) · University of Minnesota (1)
United States (10) · United Kingdom (2) · Australia (1) · Canada (1) · France (1) · Italy (1) · Spain (1)
Alaina Vidmar, MD (1) · Andrea M Haqq, MD, MHS (1) · Carine Villanueva (1) · David Meeker, MD (1) · Melanie Cree, MD, PhD (1) · Melanie Cree-Green, MD, PhD (1) · Olutoyin A Olutoye, MD (1) · Seema Kumar, MD (1)
PMID 12434728, PMID 18987268, PMID 22253363, PMID 22253364, PMID 22389380, PMID 22768009, PMID 28115006, PMID 33596993, PMID 34740373, PMID 39549719, PMID 40637175, PMID 41265832, PMID 41475815, PMID 41978152, PMID 42014131, PMID 8403734, PMID 9874695
R01DK120612 (1), R01DK144100 (1), R44DK135312 (1)