35 completed, 16 unknown, 7 recruiting, 4 enrolling by invitation. 36 Not applicable, 5 Phase 1, 5 Phase 3, 4 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Driving Performance in Parkinson's Disease and Multiple Sclerosis Using a Driving Simulator Standardized Driving Simulator Assessment - Parkinson, Multiple Sclerosis | Not yet recruiting | University Hospital Olomouc | 100 | 2026-11-01 | 2026-09-09 | |
| Transforming Parkinson's Care With Predictive Algorithms Lifestyle intervention - Parkinson | Not yet recruiting | University Ramon Llull | 200 | 2026-09-01 | 2025-12-01 | |
| Comparing Biomarker-Guided DBS Programming With Standard Clinical Monopolar Programming Conventional DBS Programming (Monopolar Review), Objective-Guided DBS Programming (Imaging and Local Field Potential-Based) - Parkinson's Disease, Parkinson | Not applicable | Not yet recruiting | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 20 | 2026-03-01 | 2026-01-27 |
| Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder PARKINSON DISEASE (Disorder), Parkinson | Recruiting | CND Life Sciences | 40 | 2025-11-04 | 2026-02-11 | |
| The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological Conditions Probiotic Supplementation with L. reuteri - PARKINSON DISEASE (Disorder), Parkinson | Not applicable | Recruiting | University of Cambridge | 215 | 2025-11-01 | 2026-08-25 |
| Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis No Intervention: Observational Cohort - PARKINSON DISEASE (Disorder), Parkinson | Recruiting | CND Life Sciences | 20 | 2025-09-03 | 2026-02-11 | |
| Effects of Otago and Frenkel's Exercises on Strengthening of Antigravity Muscles in Parkinson's Disease. Otago exercises, Frenkels exercise - Parkinson | Not applicable | Completed | University of Lahore | 40 | 2025-08-18 | 2025-12-11 |
| The Brain&Senses Study Mild Cognitive Impairment, Alzheimer Disease | Active not recruiting | University of Campania Luigi Vanvitelli | 100 | 2025-08-01 | 2026-04-23 | |
| Optimistic and Pessimistic Dopamine Signals in the Human Brain: a Mapping and Modelling Study in Health and Parkinson's Disease Healthy, Parkinson | Recruiting | Danish Research Centre for Magnetic Resonance | 140 | 2025-06-02 | 2026-02-11 | |
| Which Tools Better Predict Fall Risk in Parkinson's Disease: A Comparative Study of Objective, Self-Reported, and Functional Balance Assessment PARKINSON DISEASE (Disorder), Parkinson | Completed | Bezmialem Vakif University | 40 | 2025-05-01 | 2026-07-09 | |
| Validity and Reliability of the Standing Up From Supine Test With Parkinson's Patients Parkinson | Enrolling by invitation | Sanko University | 37 | 2025-02-01 | 2025-03-05 | |
| A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease NEU-411, Placebo - Parkinson Disease, Parkinson | Phase 2 | Recruiting | Neuron23 Inc. | 150 | 2025-01-17 | 2026-10-02 |
| Mediterranean Diet Effects on Parkinson's Disease Mediterranean Diet - Parkinson, Parkinson Disease | Not applicable | Recruiting | Università degli Studi dell'Insubria | 44 | 2025-01-17 | 2025-07-11 |
| Effects of Transcranial Pulse Stimulation in Parkinson's Disease Transcranial Pulse Stimulation (TPS) - Parkinson | Not applicable | Completed | Spaulding Rehabilitation Hospital | 14 | 2024-12-31 | 2026-08-10 |
| Digital BIOmarkers for the Assessment of Motor Status in Parkinson's Disease Patients with CLInical and ThErapeutic Application Parkinson Disease, Parkinson | Enrolling by invitation | Universidad Politecnica de Madrid | 40 | 2024-12-09 | 2025-02-20 | |
| Impact of Ketoflex 12/3 Diet on Parkinson's Disease Symptoms: A Clinical Study Ketoflex 12/3 Diet - Parkinson's Disease, Parkinson | Not applicable | Completed | Istanbul Medipol University Hospital | 40 | 2024-03-30 | 2025-04-02 |
| Digitised Home Based Care for Parkinson's Disease Digital Home Based Care pathway - Parkinson Disease, Parkinson | Not applicable | Unknown | University of Plymouth | 120 | 2024-01-01 | 2023-05-11 |
| Clinical Investigation of NMS Assist NMS Assist - Parkinson | Not applicable | Withdrawn | University of Plymouth | 2023-12-01 | 2025-06-22 | |
| Quality of Life, Anxiety and Fatigue Level of Parkison's Patients With Color Therapy Color Therapy - Parkinson | Not applicable | Completed | Ataturk University | 60 | 2023-11-01 | 2024-11-25 |
| A Pilot Comparative Bioavailability Study of Levodopa Administered Via Levodopa Cyclops® Relative to INBRIJA® Levodopa Cyclops®, INBRIJA® - Parkinson, Parkinson Disease | Phase 1 | Completed | PureIMS B.V. | 26 | 2023-09-25 | 2025-05-31 |
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Parkinson Disease (35) · Parkinsonian Disorders (6) · Alzheimer Disease (5) · Cognitive Dysfunction (5) · Dementia (3) · Motor Activity (3) · Nervous System Diseases (3) · Lewy Body Disease (2) · Multiple Sclerosis (2) · Neurodegenerative Diseases (2) · Tremor (2) · Amyotrophic Lateral Sclerosis (1) · Anosmia (1) · Antisocial Personality Disorder (1) · Asperger Syndrome (1)
Brain Diseases (42) · Central Nervous System Diseases (42) · Nervous System Diseases (40) · Basal Ganglia Diseases (37) · Movement Disorders (37) · Neurodegenerative Diseases (37) · Synucleinopathies (36) · Parkinsonian Disorders (31) · Mental Disorders (11) · Pathological Conditions, Signs and Symptoms (10) · Neurocognitive Disorders (8) · Signs and Symptoms (8) · Neurologic Manifestations (7) · Behavior (6) · Tauopathies (6)
Transcranial Magnetic Stimulation (3) · opicapone (3) · Deep Brain Stimulation (2) · Electromyography (2) · Exercise (2) · Buspirone (1) · Color Therapy (1) · Diagnostic Imaging (1) · Diet Therapy (1) · Diet, Mediterranean (1) · Dihydroxyphenylalanine (1) · Electroencephalography (1) · Exergaming (1) · Hypnosis (1) · Magnetic Resonance Spectroscopy (1)
Assistance Publique - Hôpitaux de Paris (3) · Bial - Portela C S.A. (3) · CND Life Sciences (2) · Rutgers, The State University of New Jersey (2) · Spaulding Rehabilitation Hospital (2) · Tel-Aviv Sourasky Medical Center (2) · University of Minnesota (2) · University of Plymouth (2) · Abbott Medical Devices (1) · Ahram Canadian University (1) · Ataturk University (1) · Bezmialem Vakif University (1) · Central Hospital, Nancy, France (1) · Centre Hospitalier Universitaire, Amiens (1) · Danish Research Centre for Magnetic Resonance (1)
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Andrea Pilotto, MD (1) · Anne Weissbach, MD (1) · Bahman Jabbari, MD (1) · Bryan Klassen, MD (1) · Camille Carroll, PhD (1) · Caroline Williams-Gray, Dr. (1) · Cheng-Ya Huang (1) · Chris Baeken, PhD, MD (1) · Claire Thiriez, MD (1) · Claudio Rovacchi (1) · David Meder, PhD (1) · Delaram Safarpour, MD, MSCE, FAAN (1) · Einat Even Sapir, Phd, MD (1)
PMID 11673599, PMID 12426066, PMID 15135879, PMID 20574039, PMID 22371929, PMID 23338615, PMID 23388087, PMID 24482154, PMID 25217820, PMID 26030709, PMID 26381806, PMID 26415766, PMID 27524393, PMID 27709117, PMID 28409181, PMID 28789780, PMID 29131880, PMID 29568518, PMID 29608901, PMID 30487731, PMID 30582039, PMID 30931029, PMID 31356217, PMID 31377123, PMID 31571503, PMID 32027340, PMID 32684069, PMID 32830603, PMID 32990739, PMID 33739427, PMID 34335213, PMID 34588228, PMID 34682515, PMID 34823572, PMID 34906983, PMID 34950630, PMID 35058843, PMID 35222203, PMID 35837986, PMID 36155396, PMID 37166823, PMID 37868930, PMID 37992028, PMID 38236596, PMID 38512278, PMID 38692713, PMID 38693511, PMID 38935395, PMID 39152017, PMID 40720803
2015 (1), 2023 (1), K23NS097625 (1)