7 completed, 7 unknown, 2 not yet recruiting, 2 withdrawn. 20 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 20 | Completed 7, Unknown 7, Not yet recruiting 2, Withdrawn 2, Active not recruiting 1, Terminated 1 |
Follow Panuveitis: new trials by email Literature Review of Panuveitis trials Research Report on Panuveitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adalimumab Dose Adjustment for Pediatric Uveitis Treatment Trial Adalimumab/Biosimilar - Juvenile Idiopathic Arthritis Associated Uveitis, Uveitis, Anterior | Phase 4 | Not yet recruiting | Nisha Acharya | 160 | 2026-09-01 | 2026-07-13 |
| Impact Of Upadacitinib On The Frequency Of Acute Recurrent Anterior Uveitis In Patients With Axial Spondyloarthritis Upadacitinib 15 MG [Rinvoq] - Axial Spondylarthritis (axSpA) | Phase 4 | Not yet recruiting | CARE ARTHRITIS LTD. | 200 | 2026-05-01 | 2026-02-06 |
| Loteprednol Etabonate Versus Prednisolone Acetate for Anterior Chamber Granulomas loteprednol etabonate 1% arm 1, prednisolone acete 1% - Anterior Chamber Granulomatous Uveitis | Phase 4 | Completed | Fayoum University | 66 | 2025-08-10 | 2026-03-27 |
| Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases Recombinant Herpes Zoster Vaccine (RZV), MTX Discontinuation, MMF Discontinuation - Rheumatoid Arthritis, Spondylitis, Ankylosing | Phase 4 | Active not recruiting | University of Sao Paulo General Hospital | 2005 | 2023-05-23 | 2026-05-04 |
| A Study of the Effect of Different Doses of Difluprednate Eye Drops on the Intraocular Pressure After Phacoemulsification Difluprednate Eye Drops - Uveitis, Anterior | Phase 4 | Unknown | Kafrelsheikh University | 20 | 2022-11-01 | 2022-12-13 |
| Fluocinolone Acetonide Intravitreal Implant 0.18 mg in the Treatment of Chronic Non-Infectious Posterior Segment Uveitis Fluocinolone Acetonide Intravitreal Implant 0.18 mg - Uveitis, Posterior | Phase 4 | Unknown | Alimera Sciences | 125 | 2022-06-06 | 2024-08-06 |
| Ixekizumab for the Management of Refractory Non-Infectious Uveitis: A Proof-of-Concept Study Ixekizumab Prefilled Syringe - Uveitis, Posterior, Uveitis, Anterior | Phase 4 | Unknown | Massachusetts Eye Research and Surgery Institution | 20 | 2022-06-01 | 2023-10-16 |
| Ozurdex Monotherapy Trial Ozurdex 0.7mg Ophthalmic Implant, Prednisone - Uveitis, Posterior, Uveitis, Intermediate | Phase 4 | Withdrawn | Ottawa Hospital Research Institute | 2021-11-30 | 2025-03-12 | |
| The Efficacy and Safety of Adalimumab in Non-infectious Anterior Pediatric Uveitis With Peripheral Vascular Leakage Adalimumab, Methotrexate - Uveitis, Anterior, Adalimumab | Phase 4 | Unknown | Peking Union Medical College Hospital | 50 | 2021-08-19 | 2021-11-10 |
| Six-months Versus Nine-months ATT for Ocular TB Anti-Tuberculosis Treatment - Tuberculosis (TB), Uveitis | Phase 4 | Completed | L.V. Prasad Eye Institute | 58 | 2020-01-01 | 2024-09-26 |
| Safety and Effectiveness of Acthar Gel for Inflammation of the Eye's Uvea (Middle Layer) Acthar Gel - Uveitis, Posterior, Uveitis, Intermediate | Phase 4 | Terminated | Mallinckrodt | 5 | 2018-10-05 | 2021-08-03 |
| Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation Lactated Ringer Solution, Normal Saline 0.9% Infusion Solution Bag - Fluid Loss, Symptom Complex, Triple | Phase 4 | Completed | Nicholas M Mohr | 157 | 2017-05-23 | 2018-09-11 |
| Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis H.P. ACTHAR GEL - Uveitis, Posterior, Vasculitis Retinal | Phase 4 | Unknown | Ocular Immunology and Uveitis Foundation | 40 | 2017-03-22 | 2019-09-12 |
| A Study to Assess the Effects of Certolizumab Pegol on the Reduction of Anterior Uveitis (AU) Flares in Axial Spondyloarthritis Subjects With a Documented History of AU Certolizumab Pegol - Axial Spondyloarthritis (axSpA), Anterior Uveitis (AU) | Phase 4 | Completed | UCB Biopharma SRL | 89 | 2016-12-21 | 2026-06-23 |
| Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients H.P. ACTHAR SUBCUTANEOUS GEL INJECTION - Uveitis, Anterior Uveitis | Phase 4 | Completed | Tampa Bay Uveitis Center, LLC | 6 | 2016-06-30 | 2018-07-02 |
| Study of the Effectiveness of Ozurdex for the Control of Uveitis Dexamethasone pellet - Uveitis, Intermediate, Uveitis, Posterior | Phase 4 | Completed | Johns Hopkins University | 20 | 2014-01-01 | 2019-07-05 |
| Blood-aqueous Barrier Changes After the Use of Timolol and Prostaglandin Analogues Fixed Combination in Pseudophakic Patients With POAG travoprost and timolol maleate fixed combination, latanoprost and maleate timolol fixed combination, bimatoprost and timolol maleate fixed combination - Uveitis, Anterior, Cystoid Macular Edema | Phase 4 | Completed | University of Campinas, Brazil | 69 | 2011-10-01 | 2013-11-07 |
| The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's Disease methylorednisolone, dextrose water 5% - Behcet's Disease | Phase 4 | Unknown | Tehran University of Medical Sciences | 34 | 2010-02-01 | 2011-03-02 |
| Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease flucinolone acetonide - Ocular Behcet's Disease,, Non-Infectious Uveitis | Phase 4 | Unknown | Asan Medical Center | 15 | 2008-07-01 | 2008-07-29 |
| Methotrexate in the Treatment of Axial Spondyloarthritis Methotrexate - Spondylarthropathies, Spondylitis, Ankylosing | Phase 4 | Withdrawn | Rheumatism Foundation Hospital | 120 | 2006-03-01 | 2009-01-05 |
Uveitis, Anterior (10) · Uveitis, Posterior (9) · Uveitis, Intermediate (6) · Behcet Syndrome (4) · Uveitis (4) · Retinal Vasculitis (3) · Axial Spondyloarthritis (2) · Spondylitis, Ankylosing (2) · Arthritis, Juvenile (1) · Arthritis, Rheumatoid (1) · Choroiditis (1) · Dermatomyositis (1) · Emergencies (1) · Eye Abnormalities (1)
Uveal Diseases (20) · Eye Diseases (19) · Uveitis (16) · Cardiovascular Diseases (6) · Vascular Diseases (6) · Vasculitis (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Ankylosis (4) · Arthritis (4) · Bone Diseases (4) · Genetic Diseases, Inborn (4) · Hereditary Autoinflammatory Diseases (4) · Joint Diseases (4) · Mouth Diseases (4)
Adalimumab (2) · Adrenocorticotropic Hormone (2) · Fluocinolone Acetonide (2) · Methotrexate (2) · Bimatoprost (1) · Biosimilar Pharmaceuticals (1) · Calcium Dobesilate (1) · Certolizumab Pegol (1) · Dextrans (1) · Ganfort (1) · Hypromellose Derivatives (1) · Latanoprost (1) · Loteprednol Etabonate (1) · Prednisone (1) · Ringer's Lactate (1)
Alimera Sciences (1) · Asan Medical Center (1) · CARE ARTHRITIS LTD. (1) · Fayoum University (1) · Johns Hopkins University (1) · Kafrelsheikh University (1) · L.V. Prasad Eye Institute (1) · Mallinckrodt (1) · Massachusetts Eye Research and Surgery Institution (1) · Nicholas M Mohr (1) · Nisha Acharya (1) · Ocular Immunology and Uveitis Foundation (1) · Ottawa Hospital Research Institute (1) · Peking Union Medical College Hospital (1) · Rheumatism Foundation Hospital (1)
United States (9) · Brazil (2) · Egypt (2) · Burma (1) · Canada (1) · China (1) · Czechia (1) · Finland (1) · Germany (1) · India (1) · Iran (1) · Italy (1) · Netherlands (1) · Poland (1) · South Korea (1)
Ahmed Hashem, PhD (1) · Alana M Santana, MD (1) · Antonio Cutino (1) · C. Stephen Foster, MD, FACS, FACR (1) · Farhad Shahram, Professor (1) · Grace L Clarke (1) · Jennifer E Thorne, MD, PhD (1) · Matti Laitinen, MD (1) · Meifen Zhang, MD (1) · Nisha Acharya, MD MS (1) · Walter Maksymowych, Dr. (1) · Young Hee Yoon, MD (1)
PMID 28445659, PMID 30146446, PMID 33854572, PMID 36600374, PMID 41679320, PMID 41919656, PMID 41932224, PMID 42261247, PMID 42294825, PMID 42843284
2005 (1), 2016 (1), UG1EY038172 (1)