29 completed, 18 unknown, 6 recruiting, 4 not yet recruiting. 22 Not applicable, 6 Phase 4, 5 Phase 2, 4 Phase 3, 1 Phase 1.
Follow Pancreaticoduodenectomy: new trials by email Literature Review of Pancreaticoduodenectomy trials Research Report on Pancreaticoduodenectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy pancreaticoduodenectomy - Pancreaticoduodenectomy | Not yet recruiting | Assiut University | 200 | 2026-09-30 | 2026-10-02 | |
| Postoperative Anti-infective Strategy Following Pancreaticoduodenectomy in Patients With Preoperative Biliary Stent Antibioprophylaxis (Piperacillin-tazobactam), 5 days Antibiotherapy (Piperacillin-tazobactam) - Pancreaticoduodenectomy, Antibiotherapy | Phase 3 | Not yet recruiting | University Hospital, Rouen | 326 | 2026-07-01 | 2026-06-09 |
| Omitting Nasogastric Tube Decompression in Minimally Invasive Pancreaticoduodenectomy nasogastric tube decompression, Omission of nasogastric tube decompression - Pancreaticoduodenectomy, Nasogastric Tube Decompression | Phase 2 | Not yet recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 200 | 2026-04-01 | 2026-03-12 |
| Prevention of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy by Preoperative Radiotherapy : a Phase 2 Trial Stereotactic radiotherapy / pancreaticoduodenectomy - Pancreatic Fistula, Pancreaticoduodenectomy | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 50 | 2026-02-01 | 2026-01-27 |
| Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate Pancreatic parenchymal injection of N-butyl-2- cyanoacrylate(Histoacryl®)Injection Group., Standard Pancreaticojejunostomy - Pancreaticoduodenectomy, Postoperative Pancreatic Fistula | Phase 2 | Recruiting | Minia University | 90 | 2025-12-01 | 2025-12-02 |
| Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate) Pancreatic parenchymal injection of N-butyl-2-cyanoacrylate(Histoacryl®) - Pancreaticoduodenectomy, Postoperative Pancreatic Fistula | Phase 1 | Recruiting | Minia University | 30 | 2025-08-25 | 2026-09-11 |
| ERAS Program Implementation for MIPD Conventional, ERAS - Pancreaticoduodenectomy, ERAS | Not applicable | Not yet recruiting | Seoul National University Hospital | 140 | 2025-07-15 | 2025-06-17 |
| The Effect of Celiac Axis Stenosis on Morbidity After Pancreatoduodenectomy - A Prospective Study Morbidity, Celiac Axis Stenosis | Active not recruiting | Larissa University Hospital | 99 | 2024-11-14 | 2026-02-17 | |
| Impact of External Drainage of the Main Pancreatic Duct and Common Bile Duct on Pancreatic Fistula Following Pancreaticoduodenectomy Main pancreatic duct and biliary duct external drainage, Main pancreatic duct and biliary duct internal drainage - Pancreaticoduodenectomy | Not applicable | Recruiting | Shanghai Zhongshan Hospital | 322 | 2024-05-24 | 2025-01-22 |
| In This Study, a Retrospective Analysis Was Conducted to Explore the Risk Factors for Patients Undergoing Pancreaticoduodenal Surgery (PD) to Achieve TO, and a Nomogram Prediction Model Was Further Established to Promote the Standardization and Standardization of PD Surgical Quality Evaluation. Pancreatic Carcinoma, Cholangiocarcinoma | Unknown | luokai zhang | 280 | 2024-01-01 | 2025-01-08 | |
| The Effect of PERT on Patients Undergoing Pancreaticoduodenectomy Pancreatin Enteric-coated Capsules, Routine treatment plan - Pancreatic Exocrine Insufficiency, Pancreatic Enzyme Replacement Therapy | Phase 4 | Unknown | Ruijin Hospital | 100 | 2023-11-01 | 2023-11-07 |
| Cohort Study on Nutritional, Metabolic, and Volumetric Assessment After Pancreaticoduodenectomy Pancreaticoduodenectomy - Periampullary Neoplasms, Pancreatic Cancer | Completed | Marco Aurélio Ribeiro, PhD | 44 | 2023-07-01 | 2025-09-08 | |
| Paravertebral Block vs no Block in Open Pancreaticoduodenectomy Ropivacaine - Pancreaticoduodenectomy | Phase 4 | Terminated | Mayo Clinic | 2 | 2023-04-24 | 2025-12-16 |
| The Novel Modified Cattell-Warren Duct-To-Mucosa Pancreaticojejunostomy Technique Significantly Reduces POPF. Modified Cattell-Warren duct-to-mucosa pancreaticojejunostomy, Institutional Prehabilitation Protocol - Pancreaticoduodenectomy, Distal Pancreatectomy | Completed | Nepal Medical College and Teaching Hospital | 27 | 2023-04-01 | 2025-06-26 | |
| Effect of Perioperative Neurostimulation in Patients Undergoing Whipple Operation (Pancreaticoduodenectomy) on Acute Postsurgical Inflammatory Response [ENSWAPI-trial] TENS - transcutaneous electrical nerve stimulation, Placebo - Pancreaticoduodenectomy | Not applicable | Unknown | Medical University of Graz | 90 | 2023-02-15 | 2023-02-24 |
| The Effect of Perioperative DEXamethasone on Postoperative Complications After PANcreaticoduodenectomy Dexamethasone, Saline placebo - Pancreaticoduodenectomy | Phase 4 | Completed | Ruijin Hospital | 300 | 2022-10-08 | 2023-09-18 |
| Development and Validation of a Predictive Score for Surgical Site Infections Peripheral venous blood samples - Colon or Colorectal Resection, Partial or Total Gastrectomy | Not applicable | Completed | Hopital Foch | 283 | 2022-10-06 | 2025-03-13 |
| Three-Dimensional Vascular Reconstruction of the Pancreas on Multidetector Computed Tomography Images and Its Impact on Patients Undergoing Pancreaticoduodenectomy Pancreaticoduodenectomy - Pancreaticoduodenectomy | Unknown | Institute of Liver and Biliary Sciences, India | 25 | 2022-05-30 | 2022-05-25 | |
| Comparison Between Pylorus-resecting and Preserving Pancreaticoduodenectomy on Delayed Gastric Emptying and Nutrition Pylorus resecting pancreaticoduodenectomy - Pancreaticoduodenectomy, Delayed Gastric Emptying | Not applicable | Unknown | Asan Medical Center | 394 | 2022-05-01 | 2022-04-06 |
| Different Pancreaticojejunostomy After Pancreaticoduodenectomy pancreaticojejunostomy - Pancreaticoduodenectomy, Postoperative Pancreatic Fistula | Not applicable | Unknown | Junjie Xiong | 924 | 2022-02-01 | 2022-07-26 |
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Pancreatic Neoplasms (10) · Pancreatic Fistula (8) · Gastroparesis (4) · Postoperative Complications (4) · Anastomotic Leak (3) · Diabetes Mellitus (2) · Hemorrhage (2) · Abdominal Abscess (1) · Carcinoma, Hepatocellular (1) · Cholangiocarcinoma (1) · Exocrine Pancreatic Insufficiency (1) · Fatigue (1) · Hyperamylasemia (1) · Liver Neoplasms (1) · Malnutrition (1)
Digestive System Diseases (22) · Pathological Conditions, Signs and Symptoms (21) · Pancreatic Diseases (17) · Endocrine System Diseases (12) · Digestive System Neoplasms (11) · Neoplasms (11) · Neoplasms by Site (11) · Endocrine Gland Neoplasms (10) · Pathologic Processes (10) · Digestive System Fistula (8) · Fistula (8) · Pathological Conditions, Anatomical (8) · Signs and Symptoms (6) · Gastrointestinal Diseases (4) · Neurologic Manifestations (4)
Pancreaticoduodenectomy (9) · Standard of Care (2) · Acupuncture, Ear (1) · Albumins (1) · Calorimetry, Indirect (1) · Congresses as Topic (1) · Dexamethasone (1) · Enbucrilate (1) · Enteral Nutrition (1) · Hydroxyethyl Starch Derivatives (1) · Long-Term Synaptic Depression (1) · Pancreatectomy (1) · Pancreaticojejunostomy (1) · Parenteral Nutrition (1) · Piperacillin, Tazobactam Drug Combination (1)
Asan Medical Center (2) · Chen Xiaoping (2) · Hospices Civils de Lyon (2) · Minia University (2) · Peking Union Medical College Hospital (2) · Ruijin Hospital (2) · Seoul National University Hospital (2) · Shanghai Zhongshan Hospital (2) · Tongji Hospital (2) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Azienda Ospedaliera Universitaria Integrata Verona (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Chiba University (1) · Dimitrios Vouros (1)
China (16) · France (7) · United States (7) · Greece (3) · South Korea (3) · Egypt (2) · Italy (2) · Japan (2) · Spain (2) · Austria (1) · Brazil (1) · Czechia (1) · Denmark (1) · Finland (1) · India (1)
Saleh K Saleh, MD (2) · Anderson M Navarro, Prof, PhD, MSc, BSc, RD (1) · Ayman El Nakeeb, MD (1) · Bole Tian, MD (1) · Dafang Zhang, PhD (1) · Daisuke Suzuki (1) · Dimitri A Raptis, MD, MSc, PhD (1) · Dionisios Vrochides, MD (1) · Filip Cecka, MD, PhD (1) · Filip Krag Knop, Professor (1) · Giovanni Marchegiani (1) · Giuseppe K Fusai, MD (1) · Harish Lavu, MD (1) · Ian Chik (1)
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