38 completed, 10 unknown, 8 terminated, 4 not yet recruiting. 22 Not applicable, 12 Phase 2, 3 Phase 3, 1 Early Phase 1, 1 Phase 1.
Follow Pancreaticoduodenectomy: new trials by email Literature Review of Pancreaticoduodenectomy trials Research Report on Pancreaticoduodenectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy pancreaticoduodenectomy - Pancreaticoduodenectomy | Not yet recruiting | Assiut University | 200 | 2026-09-30 | 2026-10-02 | |
| Superior Mesenteric Artery First Versus Standard Approach in Pancreaticoduodenectomy SMA-first pancreaticoduodenectomy using either right posterior or anterior approach. SMA identified and isolated with peri-adventitial dissection before any irreversible section., Conventional pancreaticoduodenectomy without prior isolation of the SMA; antero-posterior approach of the uncinate process after pancreatic section. - Pancreatic Adenocarcinoma, Pancreatic Head Cancer | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 150 | 2026-09-01 | 2026-04-23 |
| Prevention of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy by Preoperative Radiotherapy : a Phase 2 Trial Stereotactic radiotherapy / pancreaticoduodenectomy - Pancreatic Fistula, Pancreaticoduodenectomy | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 50 | 2026-02-01 | 2026-01-27 |
| Pancreatic Head Resection or Total Pancreatectomy With Islet Autotransplantation in Patients With Periampullary Cancer and High Risk Profile for the Development of Postoperative Pancreatic Fistula Intraportal transplantation of isolated autologous pancreatic islets after total pancreatectomy, Pancreaticoduodenectomy (classic Whipple or pylorus-preserving) - Periampullary Cancer, Postoperative Pancreatic Fistula | Phase 3 | Recruiting | Technische Universität Dresden | 32 | 2025-01-28 | 2026-01-30 |
| Conventional Partial Pancreatoduodenectomy Versus an Extended Pancreatoduodenectomy for Pancreatic Head Cancers Expanded pancreaticoduodenectomy surgery, Pancreaticoduodenectomy - Pancreatic Cancer Resectable | Not applicable | Not yet recruiting | First Affiliated Hospital Xi'an Jiaotong University | 270 | 2024-12-01 | 2024-11-25 |
| Pancreaticoduodenectomies With Complete Arterial Coverage by Retromesenteric Omentoplasty Pancreaticoduodenectomy without retromesenteric omental flap, Pancreaticoduodenectomy with retromesenteric omental flap - Pancreatectomy, Complication of Surgical Procedure | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 150 | 2024-10-22 | 2025-11-18 |
| Surgical Results of Resection of Locally Advanced Pancreatic Cancer Whipple operation - Pancreas Cancer | Unknown | Assiut University | 80 | 2024-01-05 | 2024-01-16 | |
| PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy Biospecimen Collection, Computed Tomography, Distal Pancreatectomy - Locally Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer American Joint Committee on Cancer v8 | Not applicable | Active not recruiting | University of Southern California | 2 | 2023-12-01 | 2025-11-25 |
| Cohort Study on Nutritional, Metabolic, and Volumetric Assessment After Pancreaticoduodenectomy Pancreaticoduodenectomy - Periampullary Neoplasms, Pancreatic Cancer | Completed | Marco Aurélio Ribeiro, PhD | 44 | 2023-07-01 | 2025-09-08 | |
| Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer Biopsy, FOLFIRINOX, Ciprofloxacin - Pancreatic Cancer | Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 25 | 2023-03-16 | 2024-10-15 |
| Three-Dimensional Vascular Reconstruction of the Pancreas on Multidetector Computed Tomography Images and Its Impact on Patients Undergoing Pancreaticoduodenectomy Pancreaticoduodenectomy - Pancreaticoduodenectomy | Unknown | Institute of Liver and Biliary Sciences, India | 25 | 2022-05-30 | 2022-05-25 | |
| Differentiation Benign and Malignant Pancreatic Lesions Whipple procedure - Pancreatic Tumor | Completed | First Affiliated Hospital of Chongqing Medical University | 864 | 2022-01-11 | 2024-10-15 | |
| Preoperative Biliary Drainage in Malignant Biliary Obstruction Preoperative drainage and pancreatoduodenectomy, Pancreatoduodenectomy - Pancreatic Cancer | Not yet recruiting | University of Pecs | 353 | 2021-09-01 | 2021-04-19 | |
| Clinically Relevant Pancreatic Fistula After Pancreaticoduodenectomy Pancreaticoduodenectomy - Pancreatic Fistula | Completed | Vo Truong Quoc | 183 | 2021-08-01 | 2024-05-17 | |
| Complication of Pancreatic Fistula and Bleeding After Pancreaticoduodenectomy in Treatment Periampullary Cancer Pancreaticoduodenectomy - Periampullary Cancer, Pancreatic Fistula | Completed | Vo Truong Quoc | 183 | 2021-08-01 | 2024-05-13 | |
| Total Tumor Mapping (TTM) for Resectable Pancreatic Cancer Pimonidazole, Surgical Resection - Pancreatic Cancer, Resectable Pancreatic Cancer | Early Phase 1 | Withdrawn | H. Lee Moffitt Cancer Center and Research Institute | 2021-04-01 | 2021-02-08 | |
| Recurrence After Whipple's (RAW) Study Pancreaticoduodenectomy - Pancreatic Cancer, Ampullary Cancer | Completed | University Hospital Plymouth NHS Trust | 1484 | 2020-10-12 | 2023-11-18 | |
| Pancreaticoduodenectomy: Outcomes of a Complex Surgical Procedure From a Developing Country pancreaticoduodenectomy - Pancreatic Cancer | Completed | Shaukat Khanum Memorial Cancer Hospital & Research Centre | 161 | 2020-01-01 | 2020-05-20 | |
| The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone pancreaticoduodenectomy - Pancreatic Cancer, Bile Duct Cancer | Not applicable | Completed | State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital | 320 | 2020-01-01 | 2026-01-21 |
| MFOLFIRINOX And Stereotactic Radiotherapy (SBRT) for Pancreatic Cancer With High Risk and Locally Advanced Disease Stereotactic Radiotherapy (SBRT), mFOLFIRINOX, Gemcitabine + Nab-paclitaxel - Pancreatic Cancer | Phase 2 | Unknown | Australasian Gastro-Intestinal Trials Group | 120 | 2019-10-01 | 2021-10-22 |
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Pancreatic Neoplasms (35) · Pancreatic Fistula (8) · Gastroparesis (4) · Diabetes Mellitus (3) · Jaundice, Obstructive (3) · Bile Duct Neoplasms (2) · Abdominal Abscess (1) · Acute Lung Injury (1) · Adenocarcinoma (1) · Carcinoma, Pancreatic Ductal (1) · Cholangiocarcinoma (1) · Fatty Liver (1) · Hemorrhage (1) · Hypoxia (1) · Metabolic Syndrome (1)
Assistance Publique - Hôpitaux de Paris (4) · Assiut University (3) · Hospital Universitari de Bellvitge (2) · National Taiwan University Hospital (2) · Southwest Hospital, China (2) · Università Vita-Salute San Raffaele (2) · Vo Truong Quoc (2) · Wakayama Medical University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Alexandria University (1) · Australasian Gastro-Intestinal Trials Group (1) · Baylor College of Medicine (1) · Benaroya Research Institute (1) · CHIR-Net (1) · Columbia University (1)
United States (15) · Spain (5) · China (4) · France (4) · Italy (4) · Pakistan (3) · United Kingdom (3) · Australia (2) · Egypt (2) · Germany (2) · India (2) · Taiwan (2) · Vietnam (2) · Austria (1) · Belgium (1)
Marco Braga, MD (2) · Wael N Abdelsalam, doctor (2) · Adam Uslu, Assoc. Prof. (1) · Anderson M Navarro, Prof, PhD, MSc, BSc, RD (1) · Andrew Oar (1) · Barbara Ludwig, Prof. Dr. (1) · Christopher L Wolfgang, MD, PhD (1) · Deirdre Cohen, MD (1) · Dimitri A Raptis, MD, MSc, PhD (1) · Dionisios Vrochides, MD PhD FACS (1) · Farah Rasheed (1) · Gazala Khan, MD (1)
PMID 21083795, PMID 23122535, PMID 27275468, PMID 27532020, PMID 28564643, PMID 28608016, PMID 28895142, PMID 29240007, PMID 30409152, PMID 30660818, PMID 30829699, PMID 31498183, PMID 32051190, PMID 32161987, PMID 32251119, PMID 32409590, PMID 32889866, PMID 33102398, PMID 33411965, PMID 34497088, PMID 35786739, PMID 36177837, PMID 36624235, PMID 38701690, PMID 39547592, PMID 40720532, PMID 40772617, PMID 42262773, PMID 6438478, PMID 7620083
2023 (1), P30CA014089 (1), R01HL131960 (1)