32 completed, 17 recruiting, 8 unknown, 7 terminated. 22 Not applicable, 15 Phase 2, 11 Phase 1, 4 Phase 3, 2 Phase 4.
Follow Pancreatic Neoplasm: new trials by email Literature Review of Pancreatic Neoplasm trials Research Report on Pancreatic Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Endoscopic Ultrasound-Guided Pulsed Electric Field Ablation for the Treatment of Pancreatic Neoplasms Clinical Intervention or Procedure, Electronic Health Record Review, Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Pancreas - Pancreatic Neoplasm, Pancreatic Neuroendocrine Tumor | Not applicable | Enrolling by invitation | Ohio State University Comprehensive Cancer Center | 12 | 2027-10-01 | 2026-10-13 |
| A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients Ascorbate, Gemcitabine, radiation therapy - Pancreatic Neoplasm | Phase 2 | Withdrawn | Joseph J. Cullen, MD, FACS | 2025-12-31 | 2025-03-10 | |
| Carbon Ion Radiotherapy in Frail Patients With Pancreatic Cancer Carbon Ion Radiotherapy - Pancreatic Neoplasm | Phase 2 | Recruiting | Yonsei University | 33 | 2025-09-23 | 2025-12-02 |
| Palliative Care Consultation to Improve Communication for Patients Considering Surgery for a Pancreatic Neoplasm Best Practice, Palliative Care Consultation, Survey Administration - Pancreatic Neoplasm | Not applicable | Withdrawn | Fred Hutchinson Cancer Center | 2025-09-01 | 2025-06-29 | |
| Prediction Model of Pancreatic Neoplasms in CP Patients With Focal Pancreatic Lesions XGBoost machine learning - Chronic Pancreatitis, Pancreatic Neoplasm | Completed | Changhai Hospital | 113 | 2025-07-01 | 2025-09-30 | |
| Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula Biospecimen Collection, Distal Pancreatectomy, Lanreotide - Pancreatic Carcinoma, Pancreatic Neoplasm | Phase 3 | Recruiting | SWOG Cancer Research Network | 274 | 2025-05-09 | 2026-03-31 |
| Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors Biospecimen Collection, Computed Tomography, Lutetium Lu 177 Dotatate - Metastatic Pancreatic Neuroendocrine Tumor, Pancreatic Neoplasm | Phase 1 | Recruiting | National Cancer Institute (NCI) | 24 | 2024-08-14 | 2026-10-20 |
| A Study of Sofe-M in Participants With Selected Advanced Solid Tumors Sofe-M, bevacizumab, carboplatin - Ovarian Neoplasms, Endometrial Neoplasms | Phase 1 | Recruiting | Eli Lilly and Company | 575 | 2024-05-20 | 2026-10-07 |
| A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression A2B694, A2B543, xT CDx with HLA-LOH Assay - Solid Tumor, Adult, Colorectal Cancer | Phase 1 / Phase 2 | Recruiting | A2 Biotherapeutics Inc. | 474 | 2024-04-03 | 2026-06-12 |
| Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals Screening Blood Tests, Endoscopic Ultrasound, Magnetic Resonance Imaging - Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma | Early Phase 1 | Recruiting | Dana-Farber Cancer Institute | 5000 | 2023-11-21 | 2026-05-29 |
| Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy Bupivacaine, Hydromorphone, Iopamidol - Duodenal Neoplasm, Pancreatic Neoplasm | Phase 2 | Recruiting | Masonic Cancer Center, University of Minnesota | 78 | 2023-11-10 | 2026-02-03 |
| Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study Chemical Ablation, Computed Tomography, Electronic Health Record Review - Pancreatic Neoplasm | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 84 | 2023-04-24 | 2026-03-23 |
| Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma mFOLFIRINOX or Gemcitabine nab-paclitaxel, Isotoxic High-Dose (iHD)-SBRT, Surgery - Pancreatic Neoplasm, Pancreatic Adenocarcinoma | Phase 2 | Recruiting | Erasme University Hospital | 256 | 2023-03-24 | 2023-05-23 |
| DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations Trastuzumab, Pertuzumab - Haematological Malignancy, Colorectal Neoplasms | Phase 2 / Phase 3 | Recruiting | Cancer Research UK | 30 | 2023-03-07 | 2025-12-02 |
| A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients with Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma Cobicistat Oral Tablet, Gemcitabin, Nab paclitaxel - CYP3A Inhibitor, Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma | Phase 1 | Terminated | German Cancer Research Center | 6 | 2022-12-07 | 2025-03-25 |
| MSCAN: ctDNA Methylation as Prognostic and Theranostic Tool for Pancreatic Cancer Pancreatic Neoplasm, Pancreas Cancer | Recruiting | Yingbin Liu, MD, PhD, FACS | 1000 | 2022-10-30 | 2025-07-01 | |
| Incremental Value of Magnetic Resonance Imaging in Selection of Pancreatic Cancer Patients for Surgery Preoperative MRI - Pancreatic Cancer, Pancreatic Neoplasm | Not applicable | Recruiting | University of Aarhus | 200 | 2022-08-30 | 2026-04-29 |
| DDP ip Combined With AG in PDAC With Peritoneal Metastasis intraperitoneal (IP) Cisplatin combined with intravenous gemcitabine + nab-paclitaxel - Pancreatic Neoplasm | Phase 2 | Completed | Fudan University | 91 | 2022-05-15 | 2025-05-22 |
| OSPREY is a Post-market, Global, Multicentre, Observational, Prospective Registry. Pancreatic Neoplasm, Digestive System Neoplasm | Recruiting | OncoSil Medical Limited | 500 | 2022-04-12 | 2024-04-30 | |
| Percutaneous Versus EUS FNAC in Pancreatic Masses US, EUS - Pancreatic Neoplasm, Pancreatic Cyst | Not applicable | Unknown | Ola Kamal Mohammed Galal | 50 | 2021-12-01 | 2021-06-14 |
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Pancreatic Neoplasms (68) · Neoplasms (8) · Colorectal Neoplasms (5) · Breast Neoplasms (4) · Lung Neoplasms (4) · Ovarian Neoplasms (4) · Colonic Neoplasms (3) · Neoplasm Metastasis (3) · Prostatic Neoplasms (3) · Adenoma, Islet Cell (2) · Carcinoma, Non-Small-Cell Lung (2) · Digestive System Neoplasms (2) · Disease (2) · Head and Neck Neoplasms (2) · Pancreatic Cyst (2)
Digestive System Diseases (67) · Endocrine Gland Neoplasms (67) · Endocrine System Diseases (67) · Neoplasms by Site (67) · Digestive System Neoplasms (66) · Pancreatic Diseases (66) · Neoplasms (60) · Gastrointestinal Diseases (10) · Pathological Conditions, Signs and Symptoms (9) · Gastrointestinal Neoplasms (8) · Intestinal Diseases (8) · Pathologic Processes (8) · Intestinal Neoplasms (7) · Neoplasms by Histologic Type (7) · Urogenital Diseases (7)
Gemcitabine (7) · Endoscopic Ultrasound-Guided Fine Needle Aspiration (5) · Magnetic Resonance Spectroscopy (4) · Specimen Handling (3) · 130-nm albumin-bound paclitaxel (2) · Biopsy (2) · Fluorouracil (2) · Pancreatectomy (2) · Radiotherapy (2) · Surgical Procedures, Operative (2) · Trastuzumab (2) · 1-phenyl-3,3-dimethyltriazene (1) · Antibodies, Monoclonal (1) · Ascorbic Acid (1) · Bevacizumab (1)
AdventHealth (4) · Azienda Ospedaliera Universitaria Integrata Verona (2) · Eli Lilly and Company (2) · National Cancer Institute (NCI) (2) · National Taiwan University Hospital (2) · Ohio State University Comprehensive Cancer Center (2) · Sanofi (2) · Yonsei University (2) · A2 Biotherapeutics Inc. (1) · Asan Medical Center (1) · Barbara Ann Karmanos Cancer Institute (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Cancer Research UK (1) · Centre Hospitalier Universitaire de Nice (1) · Centro Hospitalar De São João, E.P.E. (1)
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Shyam Varadarajulu, MD (3) · Anthony Shields, M.D. PhD (1) · Asif Khalid, MD (1) · Christelle Bouchart, MD (1) · David S Weinberg (1) · Elizabeth Loggers (1) · Frank Mortensen, MD, DMSc (1) · Jaehoon Lee, Ph.D (1) · James Flaherty (1) · Jean-Luc Van Laethem, MD (1)
PMID 20620274, PMID 22341257, PMID 21436454, PMID 22658389, PMID 23200980, PMID 23433878, PMID 23642329, PMID 25481712, PMID 26356802, PMID 27472648, PMID 27818598, PMID 27821313, PMID 29192743, PMID 29305893, PMID 30357555, PMID 31502003, PMID 32228512, PMID 32433914, PMID 32920242, PMID 32939319, PMID 33647286, PMID 34116031, PMID 34261044, PMID 36973127, PMID 37735634, PMID 37920921, PMID 38513683, PMID 40139834, PMID 41121153, PMID 42849725
2008 (1), 2014 (1), 2019 (1), P01CA084203 (1), P30CA077598 (1), UG1CA189828 (1), UG1CA189974 (1), UM1CA186689 (1)