3 completed, 2 recruiting, 1 active not recruiting, 1 enrolling by invitation. 2 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Enrolling by invitation 1, Recruiting 1 |
| Phase 2 | 2 | Active not recruiting 1, Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Osteonecrosis of the Femoral Head: new trials by email Literature Review of Osteonecrosis of the Femoral Head trials Research Report on Osteonecrosis of the Femoral Head
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Screening for Biomarkers of Osteonecrosis of the Femoral Head Osteonecrosis of the Femoral Head | Recruiting | The First Affiliated Hospital of Xinxiang Medical College | 300 | 2026-04-20 | 2026-04-22 | |
| Comparison of the Efficacy of Pericapsular Nerve Group Block Alone Versus Pericapsular Nerve Group Block Combined With Superior Cluneal and Superior Gluteal Nerve Blocks in Patients Undergoing Hip Surgery 15 ml Bupivacaine Hcl 0.25% injection, 20 mL bupivacaine 0.25% injection - Hip Osteoarthritis, Osteonecrosis of the Femoral Head | Not applicable | Enrolling by invitation | Ataturk University | 60 | 2025-09-01 | 2025-12-08 |
| Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis Core Decompression, Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate - Osteonecrosis of the Femoral Head, Avascular Necrosis of the Femoral Head | Not applicable | Recruiting | Johns Hopkins University | 192 | 2025-04-01 | 2026-09-17 |
| Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH) Core decompression, stromal vascular fraction (SVF), Hyperbaric Oxygen Therapy (HBOT) - Osteonecrosis of the Femoral Head | Completed | Ankara City Hospital Bilkent | 24 | 2025-01-22 | 2026-05-06 | |
| A Phase II Trial of RAB001 (LLP2A-Alendronate) for Steroid-Induced Early-Stage Osteonecrosis of the Femoral Head RAB001 high dose, RAB001 medium dose, RAB001 low dose - Osteonecrosis, Osteonecrosis of the Femoral Head | Phase 2 | Active not recruiting | ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. | 161 | 2024-12-24 | 2026-03-24 |
| RAB001（LLP2A-Ale） in Healthy Subjects RAB001 400 μg/kg group, RAB001 750 μg/kg group, Normal saline - Osteonecrosis of the Femoral Head | Phase 1 | Completed | ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. | 16 | 2023-02-10 | 2026-04-22 |
| PHASE II CLINICAL TRIAL Prospective, Open, Nonrandomized Treatment of Osteonecrosis of the Femoral Head by the Administration of Autologous Mesenchymal Stem Cells bone marrow aspirate - Osteonecrosis of the Femoral Head | Phase 2 | Completed | Red de Terapia Celular | 3 | 2012-07-01 | 2017-03-30 |
| Study on Autologous Osteoblastic Cells Implantation to Early Stage Osteonecrosis of the Femoral Head Core decompression/PREOB® implantation, Core decompression/placebo implantation - Osteonecrosis of the Femoral Head | Phase 3 | Terminated | Bone Therapeutics S.A | 68 | 2011-11-01 | 2022-06-24 |
Legg-Calve-Perthes Disease (8) · Osteonecrosis (4) · Femur Head Necrosis (2) · Musculoskeletal Diseases (2) · Bone Diseases (1) · Necrosis (1) · Osteoarthritis, Hip (1) · Pathologic Processes (1)
Bone Diseases (7) · Femur Head Necrosis (6) · Musculoskeletal Diseases (6) · Pathological Conditions, Signs and Symptoms (5) · Necrosis (4) · Osteonecrosis (4) · Pathologic Processes (4) · Arthritis (1) · Joint Diseases (1) · Osteoarthritis (1) · Rheumatic Diseases (1)
Alendronate (1) · Bupivacaine (1) · Hyperbaric Oxygenation (1) · Injections (1) · Population Groups (1) · Saline Solution (1)
ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. (2) · Ankara City Hospital Bilkent (1) · Ataturk University (1) · Bone Therapeutics S.A (1) · Johns Hopkins University (1) · Red de Terapia Celular (1) · The First Affiliated Hospital of Xinxiang Medical College (1)
China (3) · Turkey (Türkiye) (2) · Spain (1) · United States (1)
Lynne C Jones, PhD (1) · Michael A Mont, MD (1) · Stuart B Goodman, MD, PhD (1) · Wenjie Ren (1)
U01AR080993 (1)