6 completed, 2 unknown. 8 Phase 2, 5 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 6, Unknown 2 |
| Phase 1 | 5 | Completed 4, Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Osteoarthritis of Knee: new trials by email Literature Review of Osteoarthritis of Knee trials Research Report on Osteoarthritis of Knee
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1/2a Study to Evaluate Single Intraarticular Injections of 3 Dose Levels of SYN321 and Placebo in Patients With Symptomatic Knee Osteoarthritis SYN321, Placebo - Osteoarthritis of Knee | Phase 1 / Phase 2 | Completed | Synartro AB | 35 | 2025-08-19 | 2026-03-06 |
| A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee Cryopreserved Devitalized Adipose Tissue Allograft, Normal Saline (Placebo) - Osteoarthritis of Knee | Phase 1 / Phase 2 | Completed | Britecyte | 46 | 2025-05-05 | 2026-09-08 |
| Clinical Trial to Assess Efficacy, Tolerability of Rising Doses of Clodronate in Painful Knee Osteoarthritis Patients Clodronate, Placebo - Osteoarthritis of Knee | Phase 2 / Phase 3 | Unknown | SPA Società Prodotti Antibiotici S.p.A. | 296 | 2023-10-12 | 2024-02-16 |
| Clinical Trial to Evaluate Safety and Efficacy of MesoCellA-Ortho Tissue-Engineered Advanced Therapy Product in Patients With Osteoarthrosis and Civilisation Diseases MesoCellA-Ortho administration, HA administration - Osteoarthritis of Knee | Phase 1 / Phase 2 | Completed | Jagiellonian University | 192 | 2022-01-05 | 2024-03-21 |
| Efficacy and Safety of MM-II for Treatment of Knee Pain in Subjects With Symptomatic Knee Osteoarthritis MM-II dose I, MM-II dose II, MM-II dose III - Osteoarthritis of Knee | Phase 2 | Completed | Sun Pharmaceutical Industries Limited | 397 | 2020-12-22 | 2024-08-29 |
| Short-term Efficacy of Antidepressant in Patients Underwent TKA Duloxetine Hydrochloride - Osteoarthritis Of Knee | Phase 1 / Phase 2 | Unknown | Dalian Municipal Central Hospital | 32 | 2017-01-01 | 2017-04-14 |
| Human Autologous MSCs for the Treatment of Mid to Late Stage Knee OA 1 x 10^6 MSCs, 10 x 10^6 MSCs, 50 x 10^6 MSCs - Osteoarthritis of Knee | Phase 1 / Phase 2 | Completed | Jas Chahal | 12 | 2015-02-01 | 2019-09-27 |
| Allogeneic Mesenchymal Stem Cells in Osteoarthritis Ex- vivo cultured adult allogeneic MSCs, Plasmalyte-A - Osteoarthritis of Knee | Phase 2 | Completed | Stempeutics Research Pvt Ltd | 60 | 2011-11-01 | 2016-05-12 |
Osteoarthritis, Knee (8) · Osteoarthritis (4) · Depression (1) · Diabetes Mellitus, Type 2 (1) · Obesity (1) · Pain (1)
Arthritis (8) · Joint Diseases (8) · Musculoskeletal Diseases (8) · Rheumatic Diseases (8) · Osteoarthritis (4) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Behavior (1) · Behavioral Symptoms (1) · Body Weight (1) · Diabetes Mellitus (1) · Endocrine System Diseases (1) · Glucose Metabolism Disorders (1) · Metabolic Diseases (1) · Neurologic Manifestations (1)
Clodronic Acid (1) · Duloxetine Hydrochloride (1) · Plasmalyte A (1) · Saline Solution (1)
Britecyte (1) · Dalian Municipal Central Hospital (1) · Jagiellonian University (1) · Jas Chahal (1) · SPA Società Prodotti Antibiotici S.p.A. (1) · Stempeutics Research Pvt Ltd (1) · Sun Pharmaceutical Industries Limited (1) · Synartro AB (1)
United States (2) · Canada (1) · China (1) · Denmark (1) · Hong Kong (1) · India (1) · Italy (1) · Poland (1) · Sweden (1)
Alla Danilkovitch (1) · Bhibas Dasgupta, MS (1) · Jas Chahal, MD, MSc (1) · Krzysztof Ficek, Prof., MD, PhD, DSc (1) · Naresh Shetty, MS (1) · QI Zhiming, MD (1) · Shrikant Wagh, MD (1) · Sowmya Viswanathan, PhD (1) · Vikas Agarwal, MD., DM (1) · Vivek Pandey, MS (1)
2019 (1)