10 recruiting, 4 completed, 2 not yet recruiting, 1 active not recruiting. 7 Not applicable, 2 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Recruiting 3, Completed 2, Not yet recruiting 2 |
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Open Angle Glaucoma (OAG): new trials by email Literature Review of Open Angle Glaucoma (OAG) trials Research Report on Open Angle Glaucoma (OAG)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adaptive Optics OCT Evaluation of Rhopressa's Effects on the Retinal Ganglion Cells in Glaucoma Patients Netarsudil 0.02% Ophthalmic Solution [RHOPRESSA], Timolol Maleate 0.25% Ophthalmic Solution - Open Angle Glaucoma (OAG), Glaucoma | Phase 4 | Recruiting | Brett King | 13 | 2026-10-01 | 2026-09-29 |
| A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases Fuchs Endothelial Corneal Dysfunction, Open Angle Glaucoma (OAG) | Recruiting | Massachusetts General Hospital | 90 | 2026-08-18 | 2026-08-25 | |
| Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries Goniotomy - Open Angle Glaucoma (OAG), Primary Open Angle Glaucoma (POAG) | Not applicable | Not yet recruiting | Henry Ford Health System | 132 | 2026-07-01 | 2026-06-11 |
| iDose TR Administration in an Office-Based Surgery Setting iDose TR (travoprost intracameral implant) 75 µg - Open Angle Glaucoma (OAG), Ocular Hypertension (OHT) | Recruiting | Glaukos Corporation | 30 | 2026-05-13 | 2026-09-30 | |
| Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions) ER-100 epigenetic therapy - Open Angle Glaucoma (OAG), NAION( Non-arteritic Anterior Ischemic Optic Neuropathy) | Phase 1 | Recruiting | Life Biosciences Inc. | 18 | 2026-03-02 | 2026-05-19 |
| DSLT in Normal Tension Glaucoma (NTG) Asian Eyes Direct Selective Laser Trabeculoplasty (DSLT) - Normal Tension Glaucoma (NTG), Glaucoma | Not applicable | Not yet recruiting | Ngoc Nguyen Inc. | 40 | 2026-01-01 | 2025-12-24 |
| iStent Inject Versus Goniotomy With Kahook Dual Blade in Glauocma Treatment Goniotomy with KDB blade goniotomy, Two iStent inject implanation - Open Angle Glaucoma (OAG) | Not applicable | Recruiting | Medical University of Bialystok | 100 | 2026-01-01 | 2026-01-08 |
| Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg Travoprost - Open Angle Glaucoma (OAG), Ocular Hypertension (OH) | Recruiting | Glaukos Corporation | 30 | 2025-12-17 | 2026-02-27 | |
| Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma VisiPlate Glaucoma Implant - Open Angle Glaucoma (OAG) | Not applicable | Recruiting | Avisi Technologies Inc. | 165 | 2025-11-07 | 2026-10-07 |
| Evaluate Efficacy, Safety, Tolerability and Biodegradation of PA5346 Ocular Implant in Patients With Open-Angle Glaucoma or Ocular Hypertension PA5436 Ocular Implant, 115mcg - Open Angle Glaucoma (OAG), Ocular Hypertension (OH) | Phase 1 | Active not recruiting | PolyActiva Pty Ltd | 12 | 2025-06-10 | 2026-07-07 |
| DSLT Performance in Treatment-naïve Patients With Newly Diagnosed Open Angle Glaucoma DSLT enables newly diagnosed patients to remain well controlled and off medications - Open Angle Glaucoma (OAG) | Recruiting | Barnet Dulaney Perkins Eye Centers | 55 | 2025-03-31 | 2025-04-18 | |
| Deep Sclerectomy With Scleral Bed Fenestration Versus Trabeculectomy in Medically Uncontrolled Primary Open Angle Glaucoma Patients deep sclerectomy with scleral bed fenestration, Trabeculectomy - Open Angle Glaucoma (OAG) Surgeries, Deep Sclerectomy | Not applicable | Completed | Minia University | 39 | 2025-02-20 | 2026-09-02 |
| Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) Shunt Suprachoroidal silicone tube (SST) shunt - Glaucoma, Open Angle Glaucoma (OAG) | Recruiting | Davinci LTD | 66 | 2024-11-08 | 2024-11-15 | |
| Efficacy and Safety of Gonioscopy Assisted Transluminal Trabeculotomy in Patients with Primary Open-angle Glaucoma and Cataract. 360º goniotomy assisted transluminal trabeculotomy, Phacoemulsification, 180º gonioscopy assisted transluminal trabeculotomy - Open Angle Glaucoma (OAG) | Not applicable | Recruiting | Faculdade de Ciências Médicas de Minas Gerais | 90 | 2024-05-07 | 2025-03-07 |
| Conventional Non-Penetrating Deep Sclerectomy Versus Modified Subflap Mattress Suture in OAG Modified Deep Sclerectomy with Ahmed's sub-flap mattress suture (modified NPDS), Conventional Nonpenetrating Deep Sclerectomy (NPDS) - Open Angle Glaucoma (OAG) | Not applicable | Completed | Beni-Suef University | 26 | 2022-11-07 | 2026-02-23 |
| Safety and Performance Study of the CyPass System Applier Model 241 Open Angle Glaucoma (OAG) | Completed | Transcend Medical, Inc. | 172 | 2014-08-01 | 2023-11-15 | |
| CyPass Clinical Experience Study CyPass Micro-Stent - Open Angle Glaucoma (OAG) | Completed | Transcend Medical, Inc. | 555 | 2009-12-01 | 2017-05-15 |
Glaucoma, Open-Angle (17) · Glaucoma (9) · Ocular Hypertension (4) · Cataract (1) · Choroidal Effusions (1) · Corneal Diseases (1) · Dry Eye Syndromes (1) · Exfoliation Syndrome (1) · Keratoconus (1) · Low Tension Glaucoma (1) · Optic Nerve Diseases (1) · Retinal Diseases (1)
Eye Diseases (17) · Ocular Hypertension (13) · Glaucoma (8) · Choroid Diseases (1) · Cranial Nerve Diseases (1) · Eye Abnormalities (1) · Iris Diseases (1) · Lacrimal Apparatus Diseases (1) · Lens Diseases (1) · Nervous System Diseases (1) · Optic Nerve Diseases (1) · Uveal Diseases (1)
Trabeculectomy (3) · Ophthalmic Solutions (1) · Phacoemulsification (1) · Timolol (1) · Travoprost (1) · netarsudil (1)
Glaukos Corporation (2) · Transcend Medical, Inc. (2) · Avisi Technologies Inc. (1) · Barnet Dulaney Perkins Eye Centers (1) · Beni-Suef University (1) · Brett King (1) · Davinci LTD (1) · Faculdade de Ciências Médicas de Minas Gerais (1) · Henry Ford Health System (1) · Life Biosciences Inc. (1) · Massachusetts General Hospital (1) · Medical University of Bialystok (1) · Minia University (1) · Ngoc Nguyen Inc. (1) · PolyActiva Pty Ltd (1)
United States (9) · Egypt (2) · Germany (2) · Poland (2) · Australia (1) · Austria (1) · Brazil (1) · Bulgaria (1) · Georgia (1) · Italy (1) · South Africa (1) · Spain (1)
Amr Taha Orabi (1) · Christine Funke, Medical Doctor (1) · David A Crandall, MD (1) · Hazem Haroun (1) · Mohamed Sayed Abouzeid, MD (1) · Seok-Hyun Yun, PhD (1) · Sharon Rosenzweig-Lipson, PhD (1)
R01EY038655 (1)