101 completed, 41 unknown, 28 recruiting, 13 not yet recruiting. 80 Not applicable, 30 Phase 2, 14 Phase 4, 12 Phase 3, 8 Phase 1.
Follow Olfaction Disorders: new trials by email Literature Review of Olfaction Disorders trials Research Report on Olfaction Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SniffTrain: Effectiveness of Sniff Training in the Treatment of Post-Viral Anosmia Sniff Training Kits - Post-viral Anosmia, Anosmia | Not applicable | Not yet recruiting | University of Virginia | 204 | 2027-01-05 | 2026-10-05 |
| Effects of Olfactory Stimuli in Virtual Reality Cue Exposure on Craving and Attentional Bias in Alcohol Use Disorder VR-CE - Alcohol Use Disorder | Not applicable | Not yet recruiting | Charite University, Berlin, Germany | 60 | 2026-11-15 | 2026-10-22 |
| In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy CONVIVO system, Fluorescein injection, USP 10% - Endonasal Surgery, Endoscopic Sinus Surgery | Early Phase 1 | Not yet recruiting | Dartmouth-Hitchcock Medical Center | 36 | 2026-11-03 | 2026-10-20 |
| Olfactory Function and Model-Based Behavior in People Living With HIV and SUD HIV, Substance Use Disorder | Recruiting | National Institute on Drug Abuse (NIDA) | 120 | 2026-11-03 | 2026-10-29 | |
| Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES) Anosmia, Chronic Obstructive Pulmonary Disease | Enrolling by invitation | National Institute of Allergy and Infectious Diseases (NIAID) | 350 | 2026-11-03 | 2026-10-29 | |
| Olfactory Transcranial Focused Ultrasound transcranial focused ultrasound (tFUS) - Healthy, Olfaction | Not applicable | Recruiting | Medical University of South Carolina | 28 | 2026-10-01 | 2026-10-06 |
| Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) Respiratory Tract Infection, Smell Disorder | Recruiting | National Institute on Deafness and Other Communication Disorders (NIDCD) | 80 | 2026-10-01 | 2026-10-09 | |
| Artificial Intelligence-based Parkinson's Disease Risk Assessment (AI-PRA) Study Smartwatch and phone app - Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD) | Not yet recruiting | Queen Mary University of London | 60 | 2026-10-01 | 2026-10-02 | |
| Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label Trigeminal Nerve Stimulation-enhanced Smell Training - Olfactory Impairment | Phase 2 | Recruiting | Medical University of South Carolina | 60 | 2026-07-10 | 2026-08-12 |
| SENSILINS: Impact of Cephalic Phase Insulin Release Induced by an Environmental Food Odor Stimulus on Glucose Homeostasis According to Insulin Sensitivity Level Pleasant Food Odor Stimulation, Control Environmental Condition - Obesity & Overweight, Insulin Resistance Syndrome | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 20 | 2026-06-01 | 2026-06-10 |
| Impact of Smell Testing on Health Outcomes Patient-centered information and education - Olfactory Dysfunction, Wellbeing | Phase 2 | Recruiting | Monell Chemical Senses Center | 1000 | 2026-05-29 | 2026-10-06 |
| Slow-SPEED UK: A Double-Blind Randomised Feasibility Trial Slow-SPEED app - Hyposmia, Olfactory Dysfunction | Not applicable | Recruiting | Queen Mary University of London | 110 | 2026-05-27 | 2026-06-29 |
| PANDORA: Evaluation of Platelet-rich Plasma in Non-tumoural Odour Disorders: a Descriptive Pilot Study. Autologous Platelet-Rich Plasma (PRP) Injection - Olfactory Dysfunction, Post-traumatic Olfactory Dysfunction | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 30 | 2026-05-01 | 2026-03-20 |
| Personalized Cooking and Nutrition Guidance and Physical Activities Program to Reduce Muscle Loss in Advanced Cancer Oncology Dietitian's Standard of Care, Personalized Culinary and Nutrition Therapy - Cancer, Sarcopenia | Not applicable | Not yet recruiting | Gali Perel | 200 | 2026-04-01 | 2026-04-02 |
| Intranasal Platelet-Rich Plasma With or Without Topical Insulin for Post-Inflammatory Anosmia Intranasal PRP Plus Topical Insulin, Intranasal PRP Plus Saline (Placebo) - Anosmia, Inflammatory Anosmia | Not applicable | Not yet recruiting | Amin Javer | 20 | 2026-03-30 | 2026-02-03 |
| Feasibility of Integrating Olfactory Stimuli Into Virtual Reality Cue Exposure for Patients With Alcohol Dependence VR Cue-Exposure Including Olfactory Stimuli - Alcohol Dependence | Not applicable | Completed | Charite University, Berlin, Germany | 20 | 2026-03-07 | 2026-10-20 |
| The Effectiveness of Steroid Nasal Drops in the Olfactory Cleft Combined With Olfactory Training for Patients With PIOD Steroid nasal drops combined with olfactory training, Placebo nasal drops combined with olfactory training - Smell Dysfunction | Not applicable | Not yet recruiting | Peking University Third Hospital | 100 | 2026-03-01 | 2026-02-04 |
| Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents No Intervention: Observational Cohort - Taste Alterations, Smell Disorder | Not yet recruiting | Centre Leon Berard | 30 | 2026-02-01 | 2026-03-24 | |
| Comparing the Olfactory Perception of a Fragrance-Loaded SpECs Over Time Fragrance - Perception, Self | Not applicable | Completed | Royal College of Surgeons in Ireland - Medical University of Bahrain | 10 | 2026-02-01 | 2026-10-28 |
| Efficacy of Non-invasive Neuromodulation Treatments for COVID-19 Sequelae Non invasive neuromodulation therapy, Manual therapy, Placebo with non invasive neuromodulation - Covid-19 Recurrent | Not applicable | Not yet recruiting | Clinica Gema Leon | 104 | 2026-01-01 | 2025-09-18 |
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Anosmia (176) · COVID-19 (60) · Taste Disorders (13) · Ageusia (12) · Alzheimer Disease (9) · Dysgeusia (9) · Parkinson Disease (9) · Cognitive Dysfunction (8) · Obesity (8) · Post-Acute COVID-19 Syndrome (7) · Coronavirus Infections (6) · Depression (5) · Neoplasms (5) · Anxiety Disorders (4)
Pathological Conditions, Signs and Symptoms (209) · Signs and Symptoms (209) · Nervous System Diseases (208) · Neurologic Manifestations (207) · Sensation Disorders (207) · Respiratory Tract Diseases (72) · Infections (71) · Lung Diseases (67) · Virus Diseases (67) · Coronaviridae Infections (66) · Nidovirales Infections (66) · RNA Virus Infections (66) · Respiratory Tract Infections (66) · Pneumonia (63)
Olfactory Training (19) · Oils, Volatile (4) · Saline Solution (4) · Sodium Chloride (4) · Budesonide (3) · Smell (3) · Standard of Care (3) · Theophylline (3) · Acetylcysteine (2) · Adrenal Cortex Hormones (2) · Donepezil (2) · Insulin (2) · Mepivacaine (2) · Odorants (2) · Prednisolone (2)
Washington University School of Medicine (11) · Hospices Civils de Lyon (4) · Institut Pasteur (4) · Central Hospital, Nancy, France (3) · Johns Hopkins University (3) · Massachusetts General Hospital (3) · Medical University of South Carolina (3) · Stanford University (3) · Universitaire Ziekenhuizen KU Leuven (3) · AHS Cancer Control Alberta (2) · Ain Shams University (2) · Beth Israel Deaconess Medical Center (2) · Centre Hospitalier Universitaire de Nice (2) · Centre Hospitalier Universitaire de Nīmes (2) · Charite University, Berlin, Germany (2)
United States (67) · France (30) · Egypt (12) · Canada (11) · Italy (11) · United Kingdom (9) · China (7) · Belgium (6) · Germany (6) · Turkey (Türkiye) (6) · Spain (4) · Brazil (3) · Denmark (3) · Israel (3) · Norway (3)
Jay F Piccirillo, MD (4) · Benjamin Lallemant (2) · Bradley Goldstein, MD, PhD (2) · Davangere Devanand, M.D. (2) · Mark W Albers, MD PhD (2) · Siti Sabzah Mohd Hashim, MD MS (2) · Stefan Gutwinski, Prof. Dr. med. (2) · A KL Reyners, MD, PhD (1) · Abdelhakim F Ghallab, MD (1) · Abdelrahman A Abdelalim, MD (1) · Adam M Zanation, MD (1) · Alastair J Noyce, BMedSci, MBBS, MSc, MRCP, PhD (1)
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