8 completed, 1 recruiting, 1 withdrawn. 5 Not applicable, 2 Phase 2, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 5 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 1, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
Follow Ocular Discomfort: new trials by email Literature Review of Ocular Discomfort trials Research Report on Ocular Discomfort
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Determinants and Adverse Reactions to Tropicamide/Phenylephrine in Hospitalized Patients. Ophthalmic administration of tropicamide/phenylephrine 8 mg/50 mg/mL. - Adverse Drug Effect, Phenylephrine | Recruiting | Instituto de Oftalmología Fundación Conde de Valenciana | 1000 | 2023-09-02 | 2025-09-17 | |
| Evaluate The Improvement In Symptoms Of Patients Using Cationorm After Pterygium Surgery Cationorm single-dose eye drop, Artificial tear eye drop - Ocular Discomfort | Phase 4 | Completed | Nguyen Viet Giap | 100 | 2022-06-15 | 2025-08-06 |
| Corneal Epithelial Stem Cells and Dry Eye Disease Corneal Epithelial Stem Cell Transplant - Dry Eye Syndromes, Dry Eye | Not applicable | Completed | Sloan W. Rush, MD | 17 | 2019-02-01 | 2022-04-21 |
| Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease Lifitegrast - Ocular Discomfort, Ocular Inflammation | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2019-01-01 | 2019-05-17 | |
| Evaluation of the VisuXL® Performance on Ocular Surface Discomfort VisuXL® - Ocular Discomfort | Not applicable | Completed | VISUfarma SpA | 20 | 2018-10-08 | 2019-02-18 |
| Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease CAM-101 10%, Vehicle Control, CAM-101 30% - Dry Eye, Graft-versus-host-disease | Phase 1 / Phase 2 | Completed | Cambium Bio Limited | 64 | 2018-05-01 | 2026-06-12 |
| Safety and Efficacy of 2 Concentrations of Lubricin vs Sodium Hyaluronate in Ocular Discomfort After Refractive Surgery. Lubricin 20µg/ml, Lubricin 50µg/ml, Sodium hyaluronate 0.18% - Ocular Discomfort | Not applicable | Completed | Dompé Farmaceutici S.p.A | 30 | 2017-06-17 | 2024-12-06 |
| A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery rhNGF, Vehicle - Ocular Discomfort | Phase 2 | Completed | Dompé Farmaceutici S.p.A | 180 | 2017-01-12 | 2024-04-19 |
| Lateral Rectus Muscle Tendon Elongation LATERAL RECTUS MUSCLE AUGMENTED RECESSION BY ELONGATION OF THE TENDON WITH AUTOGRAFT FROM RESECTED MEDIAL RECTUS MUSCLE - Surgical Procedure, Unspecified, Ocular Discomfort | Not applicable | Completed | Tanta University | 16 | 2017-01-01 | 2020-02-27 |
| A Study to Evaluate the Clinical Performance of a Novel Multipurpose Solution Bausch & Lomb Multi-Purpose Solution, Ciba's Multi-Purpose Solution - Ocular Discomfort | Not applicable | Completed | Bausch & Lomb Incorporated | 312 | 2009-11-01 | 2011-08-15 |
Dry Eye Syndromes (3) · Blepharitis (1) · Drug-Related Side Effects and Adverse Reactions (1) · Exotropia (1) · Graft vs Host Disease (1) · Hypertension (1) · Jacobs syndrome (1) · Keratoconjunctivitis Sicca (1)
Eye Diseases (4) · Lacrimal Apparatus Diseases (3) · Cardiovascular Diseases (1) · Chemically-Induced Disorders (1) · Conjunctival Diseases (1) · Conjunctivitis (1) · Corneal Diseases (1) · Cranial Nerve Diseases (1) · Eyelid Diseases (1) · Immune System Diseases (1) · Keratitis (1) · Keratoconjunctivitis (1) · Nervous System Diseases (1) · Ocular Motility Disorders (1) · Strabismus (1)
Cationorm (1) · Nerve Growth Factor (1) · Ophthalmic Solutions (1) · Phenylephrine (1) · lifitegrast (1)
Dompé Farmaceutici S.p.A (2) · Bausch & Lomb Incorporated (1) · Cambium Bio Limited (1) · Instituto de Oftalmología Fundación Conde de Valenciana (1) · Nguyen Viet Giap (1) · Sloan W. Rush, MD (1) · Tanta University (1) · University of Alabama at Birmingham (1) · VISUfarma SpA (1)
Italy (3) · United States (3) · Mexico (1) · Vietnam (1)
Edmund K Waller, MD PhD (1) · Flavio Mantelli, MD-PhD (1) · Kelly K Nichols, OD MPH PhD (1) · Leonardo Mastropasqua, MD (1)