305 completed, 34 unknown, 18 recruiting, 15 terminated. 398 Phase 3, 31 Phase 2.
Follow Nose Diseases: new trials by email Literature Review of Nose Diseases trials Research Report on Nose Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) GSK5784283, Placebo, Standard of Care - Nasal Polyps | Phase 3 | Recruiting | GlaxoSmithKline | 218 | 2026-09-28 | 2026-11-05 |
| A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) GSK5784283, Placebo, Standard of Care - Nasal Polyps | Phase 3 | Recruiting | GlaxoSmithKline | 218 | 2026-09-03 | 2026-10-09 |
| Rupatifen Fumarate Capsules in Patients With Seasonal Allergic Rhinitis Rupatifen Fumarate Capsules, Rupatadine Fumarate Tablets, Rupatifen Fumarate Capsules Placebo - Seasonal Allergic Rhinitis | Phase 3 | Recruiting | Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd. | 550 | 2026-08-18 | 2026-09-09 |
| Study on the Treatment of Adolescent Patients With Seasonal Allergic Rhinitis Stapokibart, Placebo - Seasonal Allergic Rhinitis (SAR) | Phase 3 | Recruiting | Chengdu Kangnuoxing Biopharma,Inc. | 136 | 2026-08-13 | 2026-09-03 |
| A Clinical Study Evaluating the Efficacy and Safety of SHR-1819 Injection in Patients With Seasonal Allergic Rhinitis SHR-1819 Injection, SHR-1819 Injection Placebo - Seasonal Allergic Rhinitis | Phase 3 | Active not recruiting | Guangdong Hengrui Pharmaceutical Co., Ltd | 220 | 2026-08-11 | 2026-10-22 |
| Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in Adults dipyrone monohydrate 1000 mg + chlorpheniramine maleate 4 mg + caffeine 60 mg, dipyrone monohydrate 500 mg + chlorpheniramine maleate 2 mg + caffeine 30 mg, Placebo - Common Cold/Flu, Nasal Congestion | Phase 3 | Recruiting | Brainfarma Industria Química e Farmacêutica S/A | 620 | 2026-05-08 | 2026-06-16 |
| Specific Immunotherapy With Mannan-Conjugated Allergoids for HDM-Allergic Rhinitis/Rhinoconjunctivitis_MM09-SIT-063. EP-088_MM09, Placebo - Allergic Rhinitis, Allergic Rhinoconjunctivitis | Phase 3 | Recruiting | Inmunotek S.L. | 250 | 2026-04-15 | 2026-10-29 |
| Parallel, Double-dummy, Superiority Study Levocetirizine/Pseudoephedrine x Zina for Allergic Rhinitis in Brazil Administration of investigation of Eurofarma drug, Administration of Comparator - Allergic Rhinitis | Phase 3 | Withdrawn | Eurofarma Laboratorios S.A. | 2026-03-01 | 2025-12-18 | |
| Specific Immunotherapy With Mannan-Conjugated Allergoids for HDM-Allergic Rhinitis/Rhinoconjunctivitis. MM09-SIT-063. EP-088_MM09, Placebo - Allergic Rhinitis, Allergic Rhinoconjunctivitis | Phase 3 | Recruiting | Inmunotek S.L. | 250 | 2026-02-24 | 2026-10-29 |
| A Study of GR1802 Injection in Patients With Seasonal Allergic Rhinitis. GR1802 injection, Placebo - Allergic Rhinitis, Seasonal | Phase 3 | Not yet recruiting | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 144 | 2025-09-25 | 2025-09-30 |
| A Phase III Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic Rhinitis PG-011 nasal spray 0.6%(twice daily), Placebo - Seasonal Allergic Rhinitis, SAR | Phase 3 | Not yet recruiting | Prime Gene Therapeutics Co., Ltd. | 600 | 2025-09-15 | 2025-08-28 |
| A Research Study of House Dust Mite (HDM) SLIT-tablet for the Treatment of HDM Allergy in Chinese Participants Aged 12-65 HDM SLIT-tablet (12 SQ-HDM), Placebo - Allergic Rhinoconjunctivitis, Allergic Rhinitis | Phase 3 | Completed | ALK-Abelló A/S | 327 | 2025-09-01 | 2026-10-05 |
| A Study of IL4Rα Monoclonal Antibody in Patients With Seasonal Allergic Rhinitis GR1802 injection, Placebo - Allergic Rhinitis, Seasonal | Phase 3 | Recruiting | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 150 | 2025-08-15 | 2025-09-04 |
| Potency of HDM Sublingual AIT Tablets in Assuring the Persistency of Asthma Control in HDM Allergic Patients With Severe Asthma, Treated With Tezepelumab Tezepelumab, Acarizax, Placebo - Severe Asthma, Allergy to House Dust Mites | Phase 3 | Not yet recruiting | University Hospital, Montpellier | 38 | 2025-07-15 | 2025-06-10 |
| The Efficacy and Safety of Raphamin in the Treatment of Acute Rhinosinusitis in Adult Patients Raphamin, Placebo - Rhinosinusitis, Rhinosinusitis Acute | Phase 3 | Recruiting | Materia Medica Holding | 552 | 2025-04-03 | 2026-03-16 |
| Efficacy and Safety of SLIT in Patients With Rhinitis/RC With/Without Mild-moderate Asthma, Due to Dpt and/or Df Allergen Immunotherapy Extract - Rhinitis, Rhinoconjunctivitis | Phase 3 | Recruiting | Inmunotek S.L. | 736 | 2025-04-02 | 2026-01-16 |
| Study of Yupingfeng Powder Treating Allergic Rhinitis (AR) Chinese Herbal Medicine granules, Placebo - Allergic Rhinitis | Phase 2 / Phase 3 | Recruiting | Chinese University of Hong Kong | 140 | 2025-03-27 | 2026-07-27 |
| Phase II/III Seamless Clinical Study of MG-K10 Humanized Monoclonal Antibody Injection in Treatment of Seasonal Allergic Rhinitis Placebo, MG-K10 Humanized Monoclonal Antibody Injection - Seasonal Allergic Rhinitis | Phase 2 / Phase 3 | Recruiting | Shanghai Mabgeek Biotech.Co.Ltd | 160 | 2025-03-20 | 2025-04-18 |
| Efficacy and Safety of DEP114 in the Treatment of Moderate to Severe Persistent Allergic Rhinitis in Children. DEP114, Desloratadine 0.5 MG/ML - Allergic Rhinitis | Phase 3 | Not yet recruiting | EMS | 318 | 2025-02-15 | 2024-02-22 |
| A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab Tezepelumab - Chronic Rhinosinusitis With Nasal Polyps | Phase 3 | Active not recruiting | AstraZeneca | 181 | 2024-12-03 | 2026-11-03 |
Showing 20 of 398. Sign in to see all of them.
Rhinitis, Allergic, Seasonal (127) · Rhinitis, Allergic (117) · Rhinitis, Allergic, Perennial (82) · Rhinitis (44) · Nasal Polyps (34) · Hypersensitivity (30) · Sinusitis (23) · Nasal Obstruction (21) · Asthma (20) · Dust Mite Allergy (11) · Epistaxis (10) · Conjunctivitis (8) · Rhinosinusitis (8) · Common Cold (7) · Conjunctivitis, Allergic (7)
Otorhinolaryngologic Diseases (397) · Respiratory Tract Diseases (394) · Immune System Diseases (295) · Hypersensitivity, Immediate (289) · Respiratory Hypersensitivity (287) · Rhinitis (274) · Hypersensitivity (264) · Rhinitis, Allergic (164) · Infections (81) · Respiratory Tract Infections (76) · Pathological Conditions, Signs and Symptoms (63) · Paranasal Sinus Diseases (34) · Pathological Conditions, Anatomical (34) · Polyps (33)
Mometasone Furoate (42) · Fluticasone (21) · azelastine (19) · desloratadine (15) · ciclesonide (14) · montelukast (14) · Loratadine (12) · levocetirizine (11) · Beclomethasone (10) · Pseudoephedrine (8) · Cetirizine (7) · Allergens (6) · Budesonide (6) · Levofloxacin (5) · Nasal Sprays (5)
Organon and Co (46) · GlaxoSmithKline (33) · AstraZeneca (18) · ALK-Abelló A/S (17) · Meda Pharmaceuticals (14) · Sumitomo Pharma America, Inc. (10) · Inmunotek S.L. (9) · EMS (8) · Sanofi (8) · Teva Branded Pharmaceutical Products R&D, Inc. (7) · UCB Pharma (7) · Ache Laboratorios Farmaceuticos S.A. (5) · Bayer (5) · Eurofarma Laboratorios S.A. (5) · Roxall Medizin (5)
United States (131) · Germany (39) · Canada (29) · China (29) · Poland (26) · Spain (25) · Russia (20) · France (19) · Japan (18) · Brazil (15) · Belgium (14) · Italy (14) · Argentina (12) · Czechia (12) · Hungary (12)
Lewis M Fredane, MD (6) · Sudeesh Tantry, PhD (3) · Annemie Narkus, M.D. (2) · Carol Epstein, MD (2)
PMID 33710614, PMID 25685162, PMID 32926419, PMID 33548517, PMID 37951571, PMID 38197558, PMID 20819318, PMID 21439168, PMID 22737708, PMID 24836393, PMID 25788949, PMID 26364765, PMID 26507708, PMID 29656145, PMID 30027002, PMID 32548677, PMID 34379802, PMID 34382434, PMID 35639525, PMID 37214171, PMID 39035788, PMID 40037388, PMID 40626378, PMID 41461999, PMID 12086367, PMID 12100048, PMID 12668793, PMID 14674933, PMID 15023840, PMID 15049402, PMID 15313870, PMID 15316237, PMID 15461603, PMID 15510034, PMID 15516669, PMID 15679739, PMID 15750716, PMID 15898976, PMID 16890769, PMID 16930249, PMID 17178300, PMID 17274520, PMID 17405780, PMID 17619558, PMID 17620075, PMID 17620076, PMID 17651373, PMID 17882910, PMID 18155284, PMID 18164990
2017 (5), 2015 (4), 2018 (4), 2016 (3), 2023 (3), 2004 (2), 2005 (2), 2008 (2), 2019 (2), 2025 (2), 2009 (1), 2014 (1), U01AI118506 (1)