11 completed, 6 unknown, 4 terminated, 4 withdrawn. 10 Not applicable, 7 Phase 3, 6 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 4, Unknown 4, Terminated 2 |
| Phase 3 | 7 | Completed 3, Terminated 2, Unknown 2 |
| Phase 1 | 6 | Withdrawn 4, Completed 2 |
| Phase 2 | 4 | Completed 2, Withdrawn 2 |
Follow this drug Literature Review of Allergens trials Research Report on Allergens
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Beneficial Health Effects of an Additive-free Meat Product in Healthy Subjects (HIPOCARNE) Meat product without additives and allergens, Commercial meat product - Inflammation, Oxidative Stress | Not applicable | Completed | Universidad de Murcia | 58 | 2023-04-15 | 2024-05-01 |
| Bioavailability of Nasal Epinephrine Epinephrine Nasal Product, 1.6 mg, Epinephrine nasal product, 1.6 mg + allergen, Epinephrine Injection 0.3 mg - Anaphylaxis | Phase 1 | Completed | Nasus Pharma | 12 | 2020-11-01 | 2024-01-05 |
| Non-coding RNAs Analysis of Eosinophil Subtypes in Asthma Dermatophagoides pteronyssinus allergen, Blood sampling, Bronchial challenge with allergen - Allergic Asthma, Severe Eosinophilic Asthma | Not applicable | Unknown | Lithuanian University of Health Sciences | 80 | 2020-10-01 | 2020-09-09 |
| Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation Anakinra, Anakinra Matching Placebo, Dermatophagoides Farinae - Asthma | Phase 1 / Phase 2 | Withdrawn | University of North Carolina, Chapel Hill | 2020-09-01 | 2021-05-14 | |
| Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation Anakinra, Anakinra Matching Placebo, Dermatophagoides Farinae - Asthma | Phase 1 / Phase 2 | Withdrawn | University of North Carolina, Chapel Hill | 2019-08-09 | 2021-05-07 | |
| Airway Temperature Segmental Bronchoprovocation with Allergen (SBP-Ag) - Asthma | Phase 1 | Withdrawn | Lu Yuan Lee | 2018-11-08 | 2020-12-09 | |
| Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma Bronchial challenge with allergen, Co-culture formation, Inhibition of Wnt and Smad signaling pathways - Allergic Asthma, Airway Remodelling | Not applicable | Unknown | Lithuanian University of Health Sciences | 60 | 2017-06-01 | 2020-09-07 |
| The Phthalate-Allergen Immune Response Study Phthalate, Filtered Air, Allergen - Allergies | Not applicable | Unknown | University of British Columbia | 20 | 2017-02-02 | 2019-08-02 |
| Efficacy and Safety of Sublingual Immunotherapy (SLIT) sublingual immunotherapy with allergen extract, sublingual immunotherapy with placebo - Allergic Rhinitis | Phase 3 | Unknown | Roxall Medizin | 120 | 2016-11-01 | 2015-11-03 |
| Safety and Efficacy Study With Allergen Extracts of House Dust Mites for Specific Sublingual Immunotherapy Allergen extract, Placebo - Allergic Rhinitis | Phase 3 | Unknown | Roxall Medizin | 130 | 2016-09-01 | 2015-11-03 |
| Desensitization and Cross-Desensitization During Oral Grass or Ragweed Pollen Immunotherapy allergen extract tablet, Placebo tablet - Immunologic Desensitization | Phase 3 | Terminated | Virginia Commonwealth University | 58 | 2016-06-01 | 2022-03-18 |
| Intralymphatic Immunotherapy in Increasing Doses, Substudy ALK Diluent, ALK Alutard SQ 5-grasses or ALK Alutard Birch - Rhinitis, Allergic, Seasonal | Phase 2 / Phase 3 | Completed | Karolinska Institutet | 40 | 2016-05-01 | 2022-06-24 |
| A Study Investigating the Immunologic Effects and Safety of 60-day Treatment of the ALK HDM Tablets in Adult Subjects With HDM-Induced Allergic Rhinitis and/or Atopic Asthma Mitizax, Placebo - Allergy, Asthma | Phase 3 | Completed | Abbott | 112 | 2015-10-01 | 2018-03-01 |
| Eosinophil Induced Remodelling in Asthma Bronchial challenge with allergen, Co-culture formation - Allergic Asthma, Airway Remodelling | Not applicable | Completed | Lithuanian University of Health Sciences | 20 | 2014-03-01 | 2020-02-26 |
| Air Pollution and Allergens - Attenuation of Health Effects Particle Reduction Allergen, Saline, Particle depleted diesel exhaust - Allergies | Not applicable | Completed | University of British Columbia | 13 | 2014-01-01 | 2017-09-29 |
| Pilot Study of Intralymphatic Immunotherapy (ILIT) for House Dust Mite, Cat, and Dog Allergen in Allergic Rhinitis Allergen extract - Allergic Rhinitis | Phase 1 | Completed | Gachon University Gil Medical Center | 12 | 2013-11-01 | 2015-03-11 |
| Effect of Nasaleze on Nasal Challenge With Allergen Nasaleze Spray, Placebo spray, Allergen - Allergic Rhinitis | Not applicable | Terminated | University of Chicago | 14 | 2012-11-01 | 2017-01-02 |
| Effect of in Vitro Blocking the Common Beta Chain on Cell Viability in Asthma Allergen - Asthma | Completed | Hamilton Health Sciences Corporation | 10 | 2012-11-01 | 2017-07-13 | |
| Effects of Co-Exposure to Air Pollution and Allergen Allergen, Saline - Allergies | Not applicable | Completed | University of British Columbia | 18 | 2011-10-01 | 2017-09-29 |
| Repeat Dose Nasal Allergen Challenge Allergen, Placebo challenge - Allergic Rhinitis | Not applicable | Unknown | McMaster University | 30 | 2010-04-01 | 2012-11-01 |
Showing 20 of 25. Sign in to see all of them.
Asthma (9) · Rhinitis, Allergic (8) · Hypersensitivity (5) · Airway Remodeling (2) · Rhinitis (2) · Rhinitis, Allergic, Seasonal (2) · Anaphylaxis (1) · Dermatitis, Allergic Contact (1) · Dust Mite Allergy (1) · Inflammation (1) · Pulmonary Eosinophilia (1)
Lithuanian University of Health Sciences (3) · University of British Columbia (3) · University of North Carolina, Chapel Hill (3) · Roxall Medizin (2) · Abbott (1) · Fraunhofer-Institute of Toxicology and Experimental Medicine (1) · Gachon University Gil Medical Center (1) · Hamilton Health Sciences Corporation (1) · Karolinska Institutet (1) · Laboratorios Leti, S.L. (1) · Lu Yuan Lee (1) · McMaster University (1) · Mekos Laboratories AS (1) · Nasus Pharma (1) · Stallergenes Greer (1)
Canada (5) · United States (4) · Lithuania (3) · Spain (3) · Germany (2) · Belarus (1) · Hungary (1) · Israel (1) · Russia (1) · South Korea (1) · Sweden (1)
Christopher Carlsten, MD, MPH (3) · Michelle Hernandez, MD (3) · Alejandro Sanchez (1) · David Peden, MD (1) · Dmitri Kazei, MD (1) · Gail M Gauvreau, PhD (1) · Helen Neighbour, MB BS (1) · Jens Hohlfeld, MD (1) · Joseph Fowler, Prof. (1) · Kestutis Malakauskas, Prof., dr. (1) · Lars-Olaf Cardell, Professor (1) · Lawrence B Schwartz, M.D.,Ph.D. (1) · Lu Yuan Lee, PhD (1) · Mehdi Khosravi, MD (1)
PMID 19001265, PMID 19680119, PMID 21725898, PMID 22464647, PMID 22852485, PMID 22885891, PMID 23374268, PMID 24035151, PMID 24439076, PMID 26574583, PMID 26758251, PMID 27297409, PMID 27886976, PMID 28119625, PMID 30974969, PMID 31438916, PMID 31885750, PMID 32320637, PMID 32467339, PMID 34199925, PMID 34379802, PMID 36114491, PMID 37394178, PMID 37679687, PMID 39035788
R01HL135235 (2), 2009 (1), 2015 (1), U01AI123832 (1)