8 completed, 4 recruiting, 3 not yet recruiting, 1 active not recruiting. 15 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 8, Recruiting 3, Not yet recruiting 2, Active not recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Nonsuicidal Self-Injury: new trials by email Literature Review of Nonsuicidal Self-Injury trials Research Report on Nonsuicidal Self-Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of a School-Based Trauma-Informed Psychosocial Competence Intervention on Nonsuicidal Self-Injury in Adolescents Trauma-Informed Psychosocial Competence (TIPC) Program - Nonsuicidal Self-Injury | Not applicable | Not yet recruiting | Han Wu | 6000 | 2026-11-01 | 2026-10-23 |
| Psychological Treatment for Adolescents With Self-injury Within Intensive Mental Health Outpatient Services: Randomized Controlled Pilot Trial Blended ERITA, Treatment as Usual (TAU), Concomitant care - Nonsuicidal Self Injury, Nonsuicidal Self-Injury | Not applicable | Recruiting | Karolinska Institutet | 40 | 2026-09-01 | 2026-09-21 |
| Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury App-based digital mental health intervention for adolescent NSSI, App-based delivery of healthy living psychoeducational materials - Nonsuicidal Self-injury, Depression | Not applicable | Recruiting | Northwestern University | 80 | 2026-06-04 | 2026-07-08 |
| Naltrexone for Nonsuicidal Self-Injury Naltrexone 50mg (Whanin Naltrexone Tab. 50mg), Placebo - Nonsuicidal Self-Injury, Self-Injurious Behavior | Not applicable | Not yet recruiting | Seoul National University Hospital | 150 | 2026-06-01 | 2026-06-11 |
| Trial to Evaluate the Effects of Naltrexone in Nonsuicidal Self-injury Naltrexone, Placebo - Nonsuicidal Self-Injury | Phase 2 | Not yet recruiting | Seoul National University Hospital | 150 | 2026-06-01 | 2026-05-22 |
| Internet-delivered Emotion Regulation Individual Therapy or Adolescents (IERITA) With Self-injury Within Child and Adolescent Mental Health Services Adaptable IERITA, Standard IERITA, Treatment as usual - Nonsuicidal Self-Injury, Self-Harm | Not applicable | Recruiting | Karolinska Institutet | 341 | 2026-05-22 | 2026-06-08 |
| LHC-CIDI-5 in Hong Kong CIDI-5, LHC-CIDI-5 - Major Depressive Episode (MDE), Major Depressive Disorder (MDD) | Recruiting | The University of Hong Kong | 2500 | 2025-01-18 | 2026-03-10 | |
| Internet-delivered Emotion Regulation Individual Therapy or Adolescents (IERITA) With Self-injury Within Child and Adolescent Mental Health Services: Pilot Study Adaptable IERITA, Standard IERITA, Treatment as usual - Nonsuicidal Self-Injury, Self-Harm | Not applicable | Active not recruiting | Karolinska Institutet | 100 | 2025-01-15 | 2026-05-22 |
| Formal Versus Informal Mindfulness Among University Students With Self-reported ADHD, Nonsuicidal Self-injury, or Stress Formal mindfulness instruction, Informal mindfulness instruction - Nonsuicidal Self-injury, ADHD | Not applicable | Completed | McGill University | 336 | 2023-09-06 | 2025-05-06 |
| Formal Versus Informal Mindfulness Among University Students With and Without Recent Nonsuicidal Self-injury Formal mindfulness induction, Informal mindfulness induction, Active control task - Nonsuicidal Self-injury, Mindfulness | Not applicable | Completed | McGill University | 254 | 2022-11-08 | 2025-05-06 |
| Addressing Nonsuicidal Self-injury in Schools Addressing NSSI in schools, Control condition - Nonsuicidal Self-injury, Suicidal Ideation | Not applicable | Completed | Region Östergötland | 267 | 2022-01-10 | 2023-07-07 |
| Safety Planning in Juvenile Justice for Suicidal Youth Safety Planning, Standard care - Suicidal Ideation, Suicide, Attempted | Not applicable | Completed | Brown University | 59 | 2019-01-01 | 2024-11-12 |
| Interrupting Self-Harm Study Mindfulness - Nonsuicidal Self-injury | Not applicable | Withdrawn | University of Utah | 2018-06-01 | 2021-04-28 | |
| Internet Delivered ERITA for Nonsuicidal Self-Injury Emotion regulation individual therapy, Treatment as usual - Nonsuicidal Self-injury | Not applicable | Completed | Karolinska Institutet | 166 | 2017-11-20 | 2022-05-05 |
| Internet-delivered Emotion Regulation Individual Therapy for Adolescents With NSSI - An Open Pilot Study Internet-delivered Emotion Regulation Individual Therapy for Adolescents - Nonsuicidal Self-Injury | Not applicable | Completed | Karolinska Institutet | 25 | 2016-02-01 | 2018-08-10 |
| Emotion Regulation Individual Therapy for Adolescents With NSSI - An Open Pilot Study Emotion Regulation Individual Therapy for Adolescents - Nonsuicidal Self-Injury | Not applicable | Completed | Karolinska Institutet | 17 | 2014-03-01 | 2016-01-05 |
| Acceptance and Commitment Therapy for Nonsuicidal Self-injury Acceptance and Commitment Therapy (ACT) - Nonsuicidal Self-Injury, Anxiety | Not applicable | Completed | Southern Methodist University | 10 | 2012-03-19 | 2020-05-01 |
Self-Injurious Behavior (17) · Suicidal Ideation (4) · Anxiety Disorders (2) · Alcoholism (1) · Attention Deficit Disorder with Hyperactivity (1) · Bipolar Disorder (1) · Depression (1) · Depressive Disorder, Major (1) · Disruptive, Impulse Control, and Conduct Disorders (1) · Dyschromatosis symmetrica hereditaria 1 (1) · Emotional Regulation (1) · Generalized Anxiety Disorder (1) · Help-Seeking Behavior (1) · Impulsive Behavior (1) · Mania (1)
Behavior (17) · Behavioral Symptoms (17) · Suicide (4) · Mental Disorders (3) · Social Behavior (2) · Alcohol-Related Disorders (1) · Anxiety Disorders (1) · Attention Deficit and Disruptive Behavior Disorders (1) · Bipolar and Related Disorders (1) · Chemically-Induced Disorders (1) · Depressive Disorder (1) · Mood Disorders (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurodevelopmental Disorders (1)
Therapeutics (4) · Naltrexone (2) · Acceptance and Commitment Therapy (1) · Mindfulness (1) · Schools (1) · Standard of Care (1)
Karolinska Institutet (6) · McGill University (2) · Seoul National University Hospital (2) · Brown University (1) · Han Wu (1) · Northwestern University (1) · Region Östergötland (1) · Southern Methodist University (1) · The University of Hong Kong (1) · University of Utah (1)
Sweden (7) · United States (4) · Canada (2) · South Korea (2) · Hong Kong (1)
Johan Bjureberg, PhD (3) · Olivia Ojala, PhD (3) · Nancy L. Heath, Ph.D. (2) · Alicia Meuret, PhD (1) · Anthony Spirito, PhD (1) · Clara Hellner, PhD, MD (1) · Maria A Zetterqvist, PhD (1) · Michael R Riquino, MSW (1) · Michael Y. Ni, MD (1) · Yong Min Ahn, M.D, Ph.D (1)
PMID 33677832, PMID 18509902, PMID 2158355, PMID 23339875, PMID 25245352, PMID 26869941, PMID 27401883, PMID 29282024, PMID 29926087, PMID 30079928, PMID 30305103, PMID 31078660, PMID 3563494, PMID 37440232, PMID 39695442, PMID 41611448, PMID 7200102, PMID 8555746, PMID 8600226, PMID 8889912
2025 (1), K01MH131898 (1), R34MH114307 (1)