5 recruiting, 2 completed, 1 active not recruiting, 1 terminated. 5 Not applicable, 4 Phase 2, 3 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Recruiting 5 |
| Phase 2 | 4 | Completed 2, Active not recruiting 1, Unknown 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Non-ischemic Dilated Cardiomyopathy: new trials by email Literature Review of Non-ischemic Dilated Cardiomyopathy trials Research Report on Non-ischemic Dilated Cardiomyopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High Fat Diet for Cardiac Metabolic Reprogramming High fat diet, Standard diet - Non-ischemic Dilated Cardiomyopathy, Heart Failure With Reduced Ejection Fraction | Not applicable | Recruiting | Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III | 80 | 2026-01-15 | 2026-05-26 |
| Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT Nonresponders Cardiac Resynchronization Therapy Devices with Defibrillator Function (CRT-D) or CRT-D Leads Replacement, CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right and Left Ventricular Pacing, CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right Ventricular Pacing - Heart Failure, Left Bundle-Branch Block | Not applicable | Recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 30 | 2024-11-01 | 2024-11-22 |
| Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Biventricular Pacing, Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Left Bundle Branch Pacing - Heart Failure, Left Bundle-Branch Block | Not applicable | Recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 60 | 2023-10-01 | 2025-09-10 |
| Study of Personalized Allocation of Defibrillators in Non-ischemic Heart Failure (SPANISH-1) Control Strategy, Personalized precision ICD implantation Strategy based in genetic findings and CMR results - Non-ischemic Dilated Cardiomyopathy | Not applicable | Recruiting | Consorcio Centro de Investigación Biomédica en Red (CIBER) | 900 | 2023-09-06 | 2024-02-28 |
| Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated Cardiomyopathy allogeneic human mesenchymal stem cells (hMSCs), Placebo - Non-ischemic Dilated Cardiomyopathy | Phase 2 | Active not recruiting | Joshua M Hare | 107 | 2021-05-07 | 2026-09-29 |
| Cardiac Magnetic Resonance Guidance of Implantable Cardioverter Defibrillator Implantation in Non-ischemic Dilated Cardiomyopathy ICD/CRT-D implantation - Non-ischemic Dilated Cardiomyopathy | Not applicable | Recruiting | Prof. Dr. med. Ingo Eitel | 760 | 2021-01-14 | 2024-05-13 |
| The Application of the Umbilical Cord Mesenchymal Stem Cells in the Complex Treatment of Non-ischemic Heart Failure Intracoronary administration of umbilical cord-derived MSCs - Chronic Heart Failure, Non-ischemic Cardiomyopathy | Phase 1 / Phase 2 | Completed | The Research-Clinical Center for Cardiac Surgery and Transplantology LLP | 30 | 2020-03-01 | 2025-04-20 |
| Stem Cell Therapy in Non-IschEmic Non-treatable Dilated CardiomyopathiEs II: a Pilot Study Allogeneic adipose-derived stromal cells (CSCC_ASC), Control group - Non-ischemic Dilated Cardiomyopathy | Phase 1 / Phase 2 | Unknown | JKastrup | 30 | 2019-10-01 | 2021-01-19 |
| Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve Regadenoson, Adenosine - Hypertrophic Cardiomyopathy, Non-ischemic Dilated Cardiomyopathy | Phase 4 | Terminated | Duke University | 31 | 2017-09-05 | 2020-09-16 |
| PercutaneOus StEm Cell Injection Delivery Effects On Neomyogenesis in Dilated CardioMyopathy (The POSEIDON-DCM Study) Autologous hMSCs, Allogeneic hMSCs - Non-ischemic Dilated Cardiomyopathy | Phase 1 / Phase 2 | Completed | Joshua M Hare | 37 | 2011-05-19 | 2018-02-15 |
Heart Failure (5) · Bundle-Branch Block (2) · Ventricular Dysfunction, Left (2) · Ventricular Remodeling (2) · Cardiomyopathy, Dilated (1) · Cardiomyopathy, Hypertrophic (1)
Cardiovascular Diseases (6) · Heart Diseases (6) · Arrhythmias, Cardiac (2) · Cardiac Conduction System Disease (2) · Cardiomyopathies (2) · Heart Block (2) · Pathologic Processes (2) · Pathological Conditions, Anatomical (2) · Pathological Conditions, Signs and Symptoms (2) · Ventricular Dysfunction (2) · Aortic Stenosis, Subvalvular (1) · Aortic Valve Disease (1) · Aortic Valve Stenosis (1) · Cardiomegaly (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
Adenosine (1) · Cardiac Resynchronization Therapy Devices (1) · Control Groups (1) · Diet, High-Fat (1) · regadenoson (1)
Joshua M Hare (2) · Tomsk National Research Medical Center of the Russian Academy of Sciences (2) · Consorcio Centro de Investigación Biomédica en Red (CIBER) (1) · Duke University (1) · Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (1) · JKastrup (1) · Prof. Dr. med. Ingo Eitel (1) · The Research-Clinical Center for Cardiac Surgery and Transplantology LLP (1)
United States (3) · Russia (2) · Spain (2) · Denmark (1) · France (1) · Germany (1) · Italy (1) · Kazakhstan (1) · Romania (1)
Roman E Batalov, M.D. (2) · Tariel A Atabekov, Ph.D. (2) · Aziz Azkhojayev, MD (1) · Bojan Vrtovec, MD, PhD (1) · Francesco Sofi, MD PhD (1) · Han Kim (1) · Ingo Eitel, Prof. Dr. (1) · Javier Bermejo Thomas (1) · Joshua Hare, MD (1) · Joshua M Hare, MD (1)
PMID 25354998, PMID 28880460, PMID 30005555, PMID 31616309
R01HL110737 (1)