159 completed, 25 unknown, 16 terminated, 15 recruiting. 239 Phase 1, 78 Phase 2.
Follow Neurodevelopmental Disorders: new trials by email Literature Review of Neurodevelopmental Disorders trials Research Report on Neurodevelopmental Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Familial Fecal Microbiota Transplant for the Treatment of Subjects With Autism Spectrum Disorders Fecal Microbiota Transplant - Autism, Autism Spectrum Disorder | Phase 1 | Not yet recruiting | ProgenaBiome | 10 | 2027-05-01 | 2026-09-18 |
| A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep Ferrous Sulfate, Placebo - ADHD, Sleep Problems | Phase 1 / Phase 2 | Not yet recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 70 | 2027-03-01 | 2026-05-04 |
| Escalating Doses of Memantine in Down Syndrome (MEDS-123) Memantine - Down Syndrome, Intellectual Disability | Phase 1 | Not yet recruiting | University Hospitals Cleveland Medical Center | 25 | 2026-10-14 | 2026-10-05 |
| Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children 40-Hz non-invasive synchronized audiovisual stimulation - ADHD - Attention Deficit Disorder With Hyperactivity | Phase 1 | Not yet recruiting | General Hospital of Ningxia Medical University | 80 | 2026-09-15 | 2026-07-22 |
| Transcranial Ultrasound Stimulation for Tourette Syndrome Focused ultrasound stimulation, Sham stimulation - Tourette Syndrome | Phase 1 | Not yet recruiting | University of Calgary | 20 | 2026-08-01 | 2026-07-13 |
| Low Intensity Focused Ultrasound in ASD Active LIFU - Autism Spectrum Disorder | Phase 1 | Not yet recruiting | Medical University of South Carolina | 20 | 2026-07-01 | 2026-05-22 |
| GAIP ASD Research Study Umbilical Cord Blood-Derived Stem Cells and Exosomes, Glutathione - Autism Spectrum Disorder, Autism | Phase 1 | Recruiting | Greater Atlanta Integrative Pediatrics | 100 | 2026-06-01 | 2026-06-03 |
| Cannabigerol Oil for Adolescents With ADHD (CAN-ADHD) Experimental: Full-spectrum CBG oil 30 mg/mL, Placebo oil (MCT oil) - Attention-Deficit/Hyperactivity Disorder (ADHD) | Phase 1 / Phase 2 | Recruiting | Universidade do Sul de Santa Catarina | 60 | 2026-05-01 | 2026-05-18 |
| Adia Med of Winter Park LLC Autism Spectrum Disorder Research Study Umbilical Cord Blood-Derived Stem Cells and Exosomes, Glutathione - Autism Spectrum Disorder, Autism | Phase 1 | Recruiting | Adia Med of Winter Park LLC | 100 | 2026-05-01 | 2026-09-22 |
| Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined. Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol - Autism Spectrum Disorder, Autism | Phase 1 / Phase 2 | Enrolling by invitation | Black Tie Medical, Inc. | 50 | 2026-04-30 | 2026-04-27 |
| Xenon Therapy for Children With Autism Spectrum Disorder Xenon - Autism Spectrum Disorder (ASD), Autism | Phase 1 / Phase 2 | Not yet recruiting | The Children's Hospital of Zhejiang University School of Medicine | 72 | 2026-03-01 | 2026-02-27 |
| Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners ALLSTAR - Literacy, Communication, Nonverbal | Phase 1 / Phase 2 | Not yet recruiting | Penn State University | 60 | 2026-03-01 | 2026-02-03 |
| A Trial to Assess How Centanafadine Interacts With Stimulants in the Body Centanafadine, Methylphenidate, Lisdexamfetamine - ADHD | Phase 1 | Completed | Otsuka Pharmaceutical Development & Commercialization, Inc. | 40 | 2026-02-05 | 2026-05-05 |
| Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease Extended-Release Methylphenidate - Sickle Cell Disease, Executive Dysfunction | Phase 1 | Recruiting | St. Jude Children's Research Hospital | 72 | 2025-11-25 | 2026-09-09 |
| A Study of Mesenchymal Stem Cell in the Treatment of Autism Spectrum Disorder hBMMSC - Autism Spectrum Disorder | Phase 1 | Not yet recruiting | Jiuzhitang Maker (Beijing) Cell Technology Co.,Ltd. | 42 | 2025-09-30 | 2025-09-17 |
| Prospective Clinical Study on Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Childhood Autism hUC-MSC-Exos Nasal Spray - Autism Spectrum Disorder (ASD, Prospective Study | Phase 1 / Phase 2 | Recruiting | Dongfang People's Hospital | 60 | 2025-09-01 | 2026-10-16 |
| A Study to Test How BI 3031185 is Tolerated by People With Borderline Personality Disorder or Attention-deficit/Hyperactivity Disorder BI 3031185, Placebo - Borderline Personality Disorder, Attention Deficit Hyperactivity Disorder | Phase 1 | Completed | Boehringer Ingelheim | 78 | 2025-08-12 | 2026-08-10 |
| Treatment Planning for ABA Employing Auxiliary Tools V2+ (TREAAT2+) Tech-enabled ABA treatment planning - Autism Spectrum Disorder | Phase 1 / Phase 2 | Not yet recruiting | Montera Health Texas LLC | 20 | 2025-07-01 | 2024-11-22 |
| To Compare and Evaluate the Oral Bioavailability of Lisdexamfetamine 70 mg Capsule With That of Elvanse® 70 mg Capsules, Hard Lisdexamfetamine Dimesylate in Healthy, Adult, Human Subjects Under Fasting Conditions. Lisdexamfetamine capsule, Elvanse® (Lisdexamfetamine dimesylate capsules, hard) - Attention Deficit/Hyperactivity Disorder (ADHD) | Phase 1 | Completed | Humanis Saglık Anonim Sirketi | 48 | 2025-05-26 | 2025-08-01 |
| Pathways 2 Success L2B, L2B + App, skills for success - Conduct Disorder, Oppositional Defiant Disorder | Phase 1 / Phase 2 | Recruiting | University of Minnesota | 120 | 2025-03-12 | 2026-04-13 |
Showing 20 of 239. Sign in to see all of them.
Attention Deficit Disorder with Hyperactivity (78) · Autistic Disorder (68) · Autism Spectrum Disorder (65) · Intellectual Disability (17) · Tourette Syndrome (15) · Child Development Disorders, Pervasive (8) · Conduct Disorder (7) · Fragile X Syndrome (7) · Learning Disabilities (7) · Developmental Disabilities (6) · Anxiety Disorders (5) · Asperger Syndrome (5) · Speech Sound Disorder (5) · Attention Deficit and Disruptive Behavior Disorders (4)
Mental Disorders (235) · Child Development Disorders, Pervasive (102) · Attention Deficit and Disruptive Behavior Disorders (81) · Nervous System Diseases (61) · Autism Spectrum Disorder (45) · Neurologic Manifestations (42) · Pathological Conditions, Signs and Symptoms (41) · Signs and Symptoms (39) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (36) · Neurobehavioral Manifestations (35) · Genetic Diseases, Inborn (33) · Central Nervous System Diseases (26) · Behavior (25) · Brain Diseases (25)
Methylphenidate (11) · Lisdexamfetamine Dimesylate (6) · Oxytocin (6) · Fecal Microbiota Transplantation (5) · Cognitive Behavioral Therapy (4) · Dextroamphetamine (4) · 1-(naphthalen-2-yl)-3-azabicyclo(3.1.0)hexane (3) · Atomoxetine Hydrochloride (3) · Risperidone (3) · Transcranial Direct Current Stimulation (3) · balovaptan (3) · 3-(2,4-dimethoxybenzylidene)anabaseine (2) · Calcitriol (2) · Capsules (2) · Glutathione (2)
Otsuka Pharmaceutical Development & Commercialization, Inc. (8) · Hoffmann-La Roche (7) · Children's Hospital Medical Center, Cincinnati (6) · Yale University (6) · National Institute of Mental Health (NIMH) (5) · Shire (4) · Stanford University (4) · Boston Children's Hospital (3) · Duke University (3) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (3) · Aevi Genomic Medicine, LLC, a Cerecor company (2) · Chaitanya Hospital, Pune (2) · Chang Gung Memorial Hospital (2) · Ironshore Pharmaceuticals and Development, Inc (2) · Joanne Kurtzberg, MD (2)
United States (158) · Canada (11) · China (8) · United Kingdom (8) · India (6) · Israel (6) · Germany (4) · Russia (4) · Australia (3) · Brazil (3) · France (3) · Japan (3) · Taiwan (3) · Norway (2) · Spain (2)
Joanne Kurtzberg, MD (4) · Jessica Sun, MD (3) · Craig Erickson, MD (2) · Geraldine Dawson, PhD (2) · Hsiang-Yuan Lin, MD (2) · Jonathan Preston, PhD (2) · Mary Dozier, Ph.D. (2) · Scott H Kollins, Ph.D. (2) · Xue-Jun Kong, MD (2)
PMID 37811711, PMID 35690720, PMID 37120522, PMID 14605787, PMID 14662594, PMID 16554123, PMID 16930863, PMID 18625864, PMID 19948568, PMID 20145986, PMID 20680427, PMID 21356232, PMID 21883204, PMID 22537359, PMID 22588377, PMID 23106988, PMID 23978163, PMID 24297663, PMID 24439092, PMID 24472253, PMID 24664093, PMID 25313065, PMID 25436448, PMID 25526831, PMID 26336641, PMID 26397109, PMID 26493637, PMID 26541307, PMID 26547399, PMID 26631428, PMID 26913614, PMID 27711048, PMID 28122648, PMID 28639564, PMID 29039979, PMID 29339723, PMID 29386049, PMID 29792485, PMID 30153790, PMID 30196869, PMID 30230399, PMID 30659782, PMID 30967657, PMID 31370811, PMID 31677152, PMID 31763491, PMID 32082606, PMID 32242086, PMID 32616759, PMID 32731812
2019 (2), R01DC017476 (2), 2014 (1), K01MH079945 (1), K23MH081285 (1), K24DA023464 (1), P20GM148302 (1), R01AT010508 (1), R01DA011755 (1), R01DA033080 (1), R01DC010075 (1), R01DC020959 (1), R01HD076189 (1), R01HD095158 (1), R01MH052135 (1)