7 suspended. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Suspended 7 |
| Phase 2 | 4 | Suspended 4 |
Follow Nervous System Neoplasms: new trials by email Literature Review of Nervous System Neoplasms trials Research Report on Nervous System Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CA-4948 in Combination With Pembrolizumab and Stereotactic Radiosurgery to Improve Treatment of Melanoma Brain Metastases Emavusertib, Pembrolizumab, Stereotactic Radiosurgery - Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma | Phase 1 / Phase 2 | Suspended | Mayo Clinic | 23 | 2026-11-30 | 2026-10-20 |
| PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma PEP-CMV vaccine, Tetanus booster, Nivolumab - Diffuse Midline Glioma, Diffuse Midline High-grade Glioma | Phase 1 / Phase 2 | Suspended | Washington University School of Medicine | 68 | 2026-09-30 | 2026-09-11 |
| 68Ga-Dotatate PET and MRI Guided Radiation Dose Escalation for High Risk Meningioma ⁶⁸Ga-Dotatate PET and MRI Guided Radiation Therapy, Magnetic Resonance Imaging (MRI), 68Ga-Dotatate PET Imaging - High Risk Meningioma, Recurrent Meningioma | Phase 1 | Suspended | Thomas Jefferson University | 24 | 2025-09-05 | 2026-01-23 |
| Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) NaviFUS System, Lumason, Bevacizumab - Glioblastoma Multiforme, Glioblastoma | Phase 1 / Phase 2 | Suspended | NaviFUS Corporation | 10 | 2024-10-22 | 2026-09-09 |
| Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases Azeliragon, Stereotactic radiosurgery, Corticosteroid - Cancer, Metastasis | Phase 1 / Phase 2 | Suspended | Baptist Health South Florida | 46 | 2023-11-17 | 2026-06-16 |
| Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) Laparoscopically harvested omental free flap - Glioma, Glioma, Malignant | Phase 1 | Suspended | Northwell Health | 10 | 2020-01-06 | 2026-06-01 |
| Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Vestibular Schwannoma Bevacizumab (Avastin) - Vestibular Schwannoma | Phase 1 | Suspended | Northwell Health | 30 | 2011-08-01 | 2026-06-01 |
Brain Neoplasms (5) · Glioblastoma (2) · Glioma (2) · Neoplasms (2) · Diffuse Intrinsic Pontine Glioma (1) · Ependymoma (1) · Medulloblastoma (1) · Melanoma (1) · Meningioma (1) · Neoplasm Metastasis (1) · Neoplasms, Nerve Tissue (1) · Neurilemmoma (1) · Neuroma (1) · Neuroma, Acoustic (1) · Recurrence (1)
Central Nervous System Neoplasms (7) · Neoplasms by Site (7) · Nervous System Diseases (7) · Brain Diseases (6) · Central Nervous System Diseases (6) · Neoplasms by Histologic Type (6) · Neoplasms (5) · Neoplasms, Germ Cell and Embryonal (5) · Neoplasms, Nerve Tissue (5) · Neuroectodermal Tumors (5) · Neoplasms, Glandular and Epithelial (3) · Neoplasms, Neuroepithelial (3) · Astrocytoma (2) · Neuroendocrine Tumors (2)
Bevacizumab (2) · Radiosurgery (2) · Adrenal Cortex Hormones (1) · Biopsy (1) · CA-4948 (1) · Dexamethasone (1) · Fertility (1) · Immunoglobulin G (1) · Magnetic Resonance Imaging (1) · Magnetic Resonance Spectroscopy (1) · Methylprednisolone (1) · Nivolumab (1) · Specimen Handling (1) · Surveys and Questionnaires (1) · Temozolomide (1)
Northwell Health (2) · Baptist Health South Florida (1) · Mayo Clinic (1) · NaviFUS Corporation (1) · Thomas Jefferson University (1) · Washington University School of Medicine (1)
United States (7)
John Boockvar, MD (2) · Bently Doonan, MD, MS (1) · Eric M Thompson, M.D. (1) · Minesh Mehta, M.D. (1) · Wenyin Shi, MD, PhD (1)
R01CA296813 (1)