13 completed, 3 terminated, 2 active not recruiting. 18 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 18 | Completed 13, Terminated 3, Active not recruiting 2 |
| Phase 2 | 4 | Completed 2, Terminated 2 |
Follow Neoplasms, Unknown Primary: new trials by email Literature Review of Neoplasms, Unknown Primary trials Research Report on Neoplasms, Unknown Primary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers Computed Tomography, Gallium Ga 68 FAPi-46, Positron Emission Tomography - Bladder Carcinoma, Cervical Carcinoma | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 26 | 2020-08-27 | 2026-11-06 |
| Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study Biospecimen Collection, Genetic Counseling, Genetic Testing - Breast Carcinoma, Digestive System Neoplasm | Phase 1 | Completed | Mayo Clinic | 230 | 2020-06-29 | 2023-07-24 |
| A Clinical Safety and Efficacy Study of Mebendazole on GI Cancer or Cancer of Unknown Origin. ReposMBZ - Cancer of the Gastrointestinal Tract, Cancer of Unknown Origin | Phase 1 / Phase 2 | Terminated | Repos Pharma | 11 | 2018-05-25 | 2020-01-22 |
| HARE-40: HPV Anti-CD40 RNA vaccinE BNT113 - Human Papilloma Virus Related Carcinoma, Head and Neck Neoplasm | Phase 1 / Phase 2 | Completed | University of Southampton | 30 | 2017-04-11 | 2026-10-07 |
| APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors APL-501 - Solid Tumor, Microsatellite Instability | Phase 1 | Completed | Apollomics (Australia) Pty. Ltd. | 30 | 2017-03-27 | 2022-05-09 |
| Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies oxaliplatin, irinotecan hydrochloride, leucovorin calcium - Acinar Cell Adenocarcinoma of the Pancreas, Adenocarcinoma of the Gallbladder | Phase 1 | Completed | University of Chicago | 79 | 2012-03-26 | 2020-05-08 |
| Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction Carboplatin, Laboratory Biomarker Analysis, Paclitaxel - Breast Carcinoma, Carcinoma of Unknown Primary | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 94 | 2011-06-20 | 2026-11-12 |
| Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors topotecan hydrochloride - Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary | Phase 1 | Terminated | Pediatric Brain Tumor Consortium | 19 | 2005-08-01 | 2011-06-30 |
| Capecitabine, Carboplatin and Weekly Paclitaxel for Patients With Solid Tumors and Adenocarcinoma of Unknown Primary Capecitabine, Carboplatin, Paclitaxel - Tumors, Unknown Primary Tumors | Phase 1 / Phase 2 | Terminated | Ohio State University Comprehensive Cancer Center | 57 | 2005-06-01 | 2016-09-23 |
| MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma entinostat - Cancer | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 75 | 2001-03-01 | 2012-03-15 |
| Capecitabine Combined With Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid Tumors capecitabine, cisplatin - Cancer | Phase 1 | Completed | NYU Langone Health | 2000-08-01 | 2011-04-05 | |
| Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer trastuzumab, tipifarnib - Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 24 | 2000-06-01 | 2013-02-11 |
| Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum floxuridine, leucovorin calcium, oxaliplatin - Cancer | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 2000-04-01 | 2011-04-26 | |
| Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors filgrastim, docetaxel, gemcitabine hydrochloride - Bladder Cancer, Breast Cancer | Phase 1 | Completed | Dartmouth-Hitchcock Medical Center | 35 | 2000-03-01 | 2013-08-28 |
| Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu recombinant interleukin-12, ABI-007/carboplatin/trastuzumab - Advanced Adult Primary Liver Cancer, Anaplastic Thyroid Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 15 | 1999-08-01 | 2013-02-28 |
| Irinotecan and Capecitabine in Treating Patients With Solid Tumors capecitabine, irinotecan hydrochloride - Cancer | Phase 1 | Completed | Montefiore Medical Center | 30 | 1999-03-01 | 2018-09-10 |
| Aminocamptothecin in Treating Patients With Advanced Cancer of the Peritoneal Cavity aminocamptothecin colloidal dispersion - Cancer | Phase 1 | Completed | NYU Langone Health | 20 | 1998-08-01 | 2011-03-28 |
| Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer amifostine trihydrate, cisplatin, fluorouracil - Carcinoma of Unknown Primary, Head and Neck Cancer | Phase 1 / Phase 2 | Completed | University of Miami | 36 | 1988-05-01 | 2016-12-15 |
Breast Neoplasms (9) · Pancreatic Neoplasms (9) · Stomach Neoplasms (9) · Bile Duct Neoplasms (8) · Carcinoma, Hepatocellular (8) · Esophageal Neoplasms (8) · Gallbladder Neoplasms (8) · Appendiceal Neoplasms (7) · Colonic Neoplasms (7) · Neoplasms (7) · Rectal Neoplasms (6) · Uterine Cervical Neoplasms (6) · Anus Neoplasms (5) · Carcinoma, Non-Small-Cell Lung (5)
Neoplastic Processes (18) · Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Neoplasm Metastasis (17) · Neoplasms by Site (16) · Digestive System Diseases (13) · Neoplasms by Histologic Type (13) · Neoplasms, Glandular and Epithelial (13) · Carcinoma (12) · Digestive System Neoplasms (12) · Endocrine Gland Neoplasms (11) · Endocrine System Diseases (11) · Gastrointestinal Diseases (11) · Neoplasms (11) · Female Urogenital Diseases (10)
Capecitabine (3) · Paclitaxel (3) · Carboplatin (2) · Cisplatin (2) · Fluorouracil (2) · Irinotecan (2) · Leucovorin (2) · Oxaliplatin (2) · Trastuzumab (2) · Amifostine (1) · Docetaxel (1) · FAPI-46 (1) · Filgrastim (1) · Floxuridine (1) · Fluorodeoxyglucose F18 (1)
National Cancer Institute (NCI) (3) · NYU Langone Health (2) · Apollomics (Australia) Pty. Ltd. (1) · Dartmouth-Hitchcock Medical Center (1) · Jonsson Comprehensive Cancer Center (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · Montefiore Medical Center (1) · National Institutes of Health Clinical Center (CC) (1) · Ohio State University Comprehensive Cancer Center (1) · Pediatric Brain Tumor Consortium (1) · Repos Pharma (1) · University of Chicago (1) · University of Miami (1) · University of Southampton (1)
United States (15) · Australia (1) · Sweden (1) · United Kingdom (1)
Franco M. Muggia, MD (2) · Andre A. Abitbol, MD (1) · Anthony W. Tolcher, MD (1) · Christian Ottensmeier, Prof (1) · Hedy Kindler (1) · Hussein A Tawbi (1) · Ioannis Karydis, Dr (1) · Jeremie Calais (1) · Konstantin H. Dragnev, MD (1) · Leonard B. Saltz, MD (1) · Marietta Franco (1) · Niloy J Samadder (1) · Shivaani Kummar, MD (1) · Sridhar Mani, MD (1) · Susan M. Blaney, MD (1)
P30CA016087 (2), 2014 (1), N01CM00100 (1), P30CA013330 (1), P30CA023108 (1), P30CA047904 (1), U01CA062490 (1), U01CA062502 (1), U01CA062505 (1), U01CA069856 (1), U01CA070095 (1), U01CA076576 (1), U01CA076642 (1), U01CA081457 (1), U01CA099168 (1)