13 completed, 11 recruiting, 5 not yet recruiting, 1 active not recruiting. 22 Not applicable, 4 Phase 2, 2 Phase 1, 1 Early Phase 1, 1 Phase 4.
Follow Multiple Sclerosis (MS) - Relapsing-remitting: new trials by email Literature Review of Multiple Sclerosis (MS) - Relapsing-remitting trials Research Report on Multiple Sclerosis (MS) - Relapsing-remitting
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MS Remibrutinib (Open Label) - Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Secondary Progressive | Phase 2 | Not yet recruiting | Moein Amin | 20 | 2027-03-01 | 2026-08-19 |
| Multicenter Prospective Study Analyzing the Occurrence of Multiple Sclerosis Relapses Without Radiological Evidence: Myth or Reality? Early Cerebro-spinal MRI, Biomarker Assessment, Clinical and Neuropsychological Evaluations - Multiple Sclerosis, RRMS | Not applicable | Not yet recruiting | University Hospital, Strasbourg, France | 136 | 2026-09-01 | 2026-04-22 |
| Brain Imaging and Immune Changes During Remibrutinib Treatment in Multiple Sclerosis. Remibrutinib, Ocrelizumab (US) - Multiple Sclerosis (MS) - Relapsing-remitting | Recruiting | Washington University School of Medicine | 15 | 2026-08-15 | 2026-08-11 | |
| Effects of Low-Load Blood Flow Restriction Exercise on Rectus Femoris Muscle Morphology in Individuals With Relapsing-Remitting Multiple Sclerosis Blood Flow Restriction Training, Sham Blood Flow Restriction, Low-Load Exercise Program - Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Not yet recruiting | Hanifi Bal | 30 | 2026-07-01 | 2026-06-12 |
| Acute Intermittent Hypoxia Combined With Gait Training in Multiple Sclerosis Acute Intermittent Hypoxia (AIH), Sham Acute Intermittent Hypoxia (AIH), Myoelectric Interface Neurorehabilitation Training (MINT) - Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Not yet recruiting | Shirley Ryan AbilityLab | 35 | 2026-06-15 | 2026-06-08 |
| RESET-MS: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Multiple Sclerosis CABA-201 - Relapsing Multiple Sclerosis (RMS), Progressive Multiple Sclerosis (PMS) | Phase 1 / Phase 2 | Withdrawn | Cabaletta Bio | 2026-06-01 | 2026-06-25 | |
| Exploration of Novel Imaging Biomarkers on OCT for Ublituximab Treatment Response in Multiple Sclerosis Ublituximab, Other disease modifying therapies - Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Recruiting | University of Maryland, Baltimore | 30 | 2026-05-01 | 2026-07-29 |
| Healthy Eating and Active Living for People Living With Multiple Sclerosis (HEAL MS): A Lifestyle Program for People With Multiple Sclerosis Multi-Domain Lifestyle Intervention - Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis | Not applicable | Not yet recruiting | New York University Abu Dhabi | 30 | 2026-04-15 | 2026-05-15 |
| Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study wearable focal vibration therapy - Multiple Sclerosis (MS) - Relapsing-remitting, Upper Extremity Dysfunction | Not applicable | Recruiting | University of Florida | 15 | 2026-03-04 | 2026-03-06 |
| Myrosinase Bioactivated Gglucoraphanin for the Treatment of Neurodegenerative Diseases (GRA-MYR-ND) bioactivated GRA for adult patients, bioactivated GRA for pediatric patients - PARKINSON DISEASE (Disorder), Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Recruiting | IRCCS Centro Neurolesi Bonino Pulejo | 300 | 2026-01-01 | 2026-01-22 |
| Monthly Monitoring of Plasma NfL in Treated Relapsing-remitting Multiple Sclerosis to Detect Persistent Infraclinical Disease Activity Monthly pNfL monitoring - Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Recruiting | Centre Hospitalier Universitaire de Nīmes | 84 | 2025-12-12 | 2026-06-18 |
| Combined Motor Imagery and Vestibular Rehab for MS Motor Imagery + Vestibular Rehabilitation group, Conventional therapy group - Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Recruiting | Medipol University | 30 | 2025-12-01 | 2026-04-30 |
| Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis Ublituximab - Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting | Phase 4 | Recruiting | Northwestern University | 40 | 2025-11-28 | 2026-03-17 |
| Home Based Functional Balance Intervention for Multiple Sclerosis Multicomponent balance intervention consisting of four components including dual-tasking, functional strength, vestibular and dynamic balance., Stretching - Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Recruiting | University of Illinois at Chicago | 75 | 2025-11-24 | 2026-01-21 |
| Effects of Ublituximab on Motor Functions in Multiple Sclerosis Ublituximab - Multiple Sclerosis (MS) - Relapsing-remitting | Early Phase 1 | Recruiting | Georgia State University | 25 | 2025-11-13 | 2026-02-09 |
| "Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting | Recruiting | University of California, San Francisco | 300 | 2025-10-01 | 2025-10-31 | |
| Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: the ADVICE Protocol Study (Phase 2) Strength training, nutrition, and behavioral training, Self-Guided and Unsupervised Program with General Recommendations - Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Completed | Universidad de Almeria | 40 | 2025-04-15 | 2026-09-30 |
| MS Synchronous vs Asynchronous Exercise Study Combined Exercise Program (Synchronous Delivery), Combined Exercise Program (Asynchronous Delivery) - Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Completed | Yeditepe University | 16 | 2025-04-01 | 2026-01-21 |
| Study to Investigate Vagus Nerve Stimulation Paired With Motor Task for Remyelination and Functional Recovery Closed Loop Trans-Auricular Vagus Nerve Stimulation System, Placebo - Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis | Not applicable | Enrolling by invitation | University of Colorado, Denver | 70 | 2025-01-21 | 2026-07-06 |
| Comparison of Efficacy and Safety in Patients Switching From MabThera® to Rixathon® in Relapsing-Remitting Multiple Sclerosis MS (Multiple Sclerosis), Multiple Sclerosis (MS) - Relapsing-remitting | Active not recruiting | Uppsala University | 184 | 2025-01-01 | 2025-11-19 |
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Multiple Sclerosis, Relapsing-Remitting (35) · Multiple Sclerosis (24) · Fatigue (8) · Multiple Sclerosis, Chronic Progressive (8) · Anxiety Disorders (3) · Cognitive Dysfunction (3) · Depression (3) · Disease Progression (2) · Motor Activity (2) · Neuroinflammatory Diseases (2) · Parkinson Disease (2) · Acne Vulgaris (1) · Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1) · Arthritis, Rheumatoid (1)
Autoimmune Diseases of the Nervous System (35) · Demyelinating Autoimmune Diseases, CNS (35) · Demyelinating Diseases (35) · Immune System Diseases (35) · Nervous System Diseases (35) · Autoimmune Diseases (34) · Pathological Conditions, Signs and Symptoms (18) · Multiple Sclerosis (11) · Pathologic Processes (11) · Signs and Symptoms (11) · Disease Attributes (9) · Chronic Disease (8) · Behavior (5) · Mental Disorders (5) · Neurocognitive Disorders (4)
ublituximab (3) · remibrutinib (2) · Alemtuzumab (1) · Blood Flow Restriction Therapy (1) · Cognitive Behavioral Therapy (1) · Dimethyl Fumarate (1) · Extracorporeal Shockwave Therapy (1) · Fingolimod Hydrochloride (1) · Metformin (1) · Natalizumab (1) · Nutritional Status (1) · Resistance Training (1) · Sirolimus (1) · Transcranial Direct Current Stimulation (1) · ocrelizumab (1)
Universidad de Almeria (3) · Cabaletta Bio (1) · Centre Hospitalier Universitaire de Nīmes (1) · Ege University (1) · Firat University (1) · Furkan Bilek (1) · Georgia State University (1) · German University in Cairo (1) · Hacettepe University (1) · Hanifi Bal (1) · IRCCS Centro Neurolesi Bonino Pulejo (1) · Istinye University (1) · Istituto Auxologico Italiano (1) · Medipol University (1) · Moein Amin (1)
United States (11) · Turkey (Türkiye) (7) · Spain (3) · France (2) · Italy (2) · Denmark (1) · Egypt (1) · Greece (1) · Mexico (1) · Sweden (1) · United Arab Emirates (1)
Antonia Kaltsatou, PhD (1) · Daniel Harrison, MD (1) · Emanuela Mazzon (1) · Eric Thouvenot (1) · Farrah J Mateen, MD, PhD (1) · Hongwu Wang (1) · Jeffrey Bennett, MD (1) · Joachim Burman, MD, PhD (1) · Matthew R Brier, MD, PhD (1) · Milap Sandhu, PT, PhD (1) · Moein Amin, MD, MS (1)
PMID 32098162, PMID 35483736, PMID 39855661, PMID 41483718, PMID 42462809