9 completed, 7 unknown, 6 not yet recruiting, 5 recruiting. 30 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 30 | Completed 9, Unknown 7, Not yet recruiting 6, Recruiting 5, Active not recruiting 2, Enrolling by invitation 1 |
Follow MCI: new trials by email Literature Review of MCI trials Research Report on MCI
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Developing and Testing an AI-Based Cognitive Intervention Program Lifestyle Intervention - Intact Cognitive Function, MCI | Not applicable | Not yet recruiting | National Research Center for Rehabilitation Technical Aids | 100 | 2026-11-01 | 2026-08-18 |
| Personalized Closed-Loop Brain Stimulation for Patients With Mild Cognitive Impairment Active tES, Cognitive Interventions - MCI | Not applicable | Not yet recruiting | Johns Hopkins University | 10 | 2026-11-01 | 2026-10-07 |
| Cognitive-Motor Training for AD/ADRD Prevention Novel CogXergaming Training, Exercise and Education Training Program - MCI, Aging | Not applicable | Not yet recruiting | University of Illinois at Chicago | 46 | 2026-10-01 | 2026-08-18 |
| Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention BLAZE (Brain health Lifestyle Action with personaliZed Engagement) - MCI, Dementia | Not applicable | Not yet recruiting | Alexandra Hospital | 350 | 2026-09-01 | 2026-05-29 |
| The Effect of Lavender Aromatherapy on Cognitive Function in Older Adults With Mild Cognitive Impairment aromatherapy - MCI | Not applicable | Not yet recruiting | China Medical University, China | 70 | 2026-09-01 | 2026-07-07 |
| Ketogenic Diet to Reduce Osteoarthritis Pain in MCI Well-formulated ketogenic diet - Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee | Not applicable | Not yet recruiting | University of Kansas Medical Center | 10 | 2026-06-01 | 2026-05-04 |
| Telehealth-Adapted Compensatory Training and Intervention for Cognition Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT-MCI), Brief Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (bME-CCT-MCI) - MCI, Mild Cognitive Impairment | Not applicable | Recruiting | University of Florida | 100 | 2026-05-29 | 2026-06-03 |
| Prevalence of Mild Cognitive Impairment and Dementia in Patients Admitted to Non-neurological Rehabilitation Wards Cognitive and clinical screening, Extended neuropsychological assessment, Blood biomarker sampling and APOE genotyping - MCI, Mild Cognitive Impairment (MCI) | Not applicable | Recruiting | Fondazione Don Carlo Gnocchi ETS | 384 | 2026-01-20 | 2026-08-10 |
| Validation Study of a New Digital Diagnostic and Treatment Test Based on Interactive Video Games for Alzheimer's Disease Bgaze Therapy, Bgaze Attention Task - Alzheimer Disease, MCI | Not applicable | Enrolling by invitation | Braingaze | 60 | 2025-05-01 | 2025-05-09 |
| Acute Oral Ketone Monoester Supplementation and Resting-state Brain Connectivity Oral ketone monoester (KME) - MCI, SCD | Not applicable | Completed | University Department of Geriatric Medicine FELIX PLATTER | 15 | 2025-04-12 | 2026-05-18 |
| ViewMind Atlas Cognition ViewMind Atlas™ - MCI, Cognitive Ability, General | Not applicable | Unknown | ViewMind | 270 | 2024-10-16 | 2024-12-24 |
| Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults MediTrain, wrist worn multi-sensor watches, Sleep monitor - MCI, Aging | Not applicable | Active not recruiting | University of California, San Francisco | 90 | 2024-09-10 | 2026-08-24 |
| Accelerating Cognitive Gains From Digital Inverventions With Noninvasive Brain Stimulation MediTrain, Worder, noninvasive neurostimulation device - Aging, MCI | Not applicable | Active not recruiting | University of California, San Francisco | 90 | 2024-08-31 | 2026-08-24 |
| Enhancing Attention and Wellbeing Using Digital Therapeutics MediTrain, Worder - Aging, MCI | Not applicable | Recruiting | University of California, San Francisco | 4000 | 2024-04-01 | 2026-08-24 |
| Neuromodulation of Memory in Aging Transcranial Magnetic Stimulation - Mild Cognitive Impairment, MCI | Not applicable | Recruiting | Indiana University | 150 | 2024-03-28 | 2026-08-11 |
| Cognitive Therapy Software for Improving Cognitive Function for Patients With Mild Cognitive Impairment SB-100, Educational book - Mild Cognitive Impairment, MCI | Not applicable | Completed | Rowan | 140 | 2024-01-15 | 2025-10-02 |
| Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults Fitbit wearing, with notification for sleep, activity and nutrition based fitbit data, Routine care - Cognition Disorders in Old Age, Cognitive Function | Not applicable | Completed | Tokyo University | 355 | 2023-11-08 | 2026-04-16 |
| iPACES v3 MCI NIA Protocol Copied for iPACES v4 PD NINDS iPACES (interactive Physical and Cognitive Exercise System), PACE (Physical and Cognitive Exercise) - Parkinson's Disease, PD | Not applicable | Unknown | iPACES LLC | 120 | 2023-08-01 | 2023-04-12 |
| Effects and Mechanism of the Fully Immersive Virtual Reality Cognitive Training Based on Leisure Activities VR cognitive training, Traditional cognitive training - MCI, SCD | Not applicable | Unknown | Chang Gung Memorial Hospital | 275 | 2023-01-01 | 2023-01-12 |
| A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (HOPE Study) Spectris™ AD - Active, Spectris™ AD - Sham - Alzheimer Disease, Alzheimer Disease 1 | Not applicable | Completed | Cognito Therapeutics, Inc. | 673 | 2022-12-13 | 2026-09-09 |
Showing 20 of 30. Sign in to see all of them.
Cognitive Dysfunction (15) · Dementia (7) · Alzheimer Disease (6) · Motor Activity (3) · Nerve Degeneration (2) · Alzheimer Disease 10 (1) · Alzheimer Disease 11 (1) · Alzheimer Disease 12 (1) · Alzheimer Disease 13 (1) · Alzheimer Disease 14 (1) · Alzheimer Disease 15 (1) · Alzheimer Disease 16 (1) · Alzheimer Disease 5 (1) · Alzheimer Disease 6 (1) · Alzheimer Disease 7 (1)
Mental Disorders (19) · Neurocognitive Disorders (18) · Cognition Disorders (14) · Nervous System Diseases (14) · Brain Diseases (13) · Central Nervous System Diseases (13) · Neurodegenerative Diseases (7) · Tauopathies (6) · Dementia (5) · Pathological Conditions, Signs and Symptoms (4) · Behavior (3) · Neurologic Manifestations (3) · Pathologic Processes (3) · Signs and Symptoms (3) · Aphasia (1)
Exercise (2) · Physical Examination (2) · Aromatherapy (1) · Speech Therapy (1) · Transcranial Magnetic Stimulation (1)
University of California, San Francisco (3) · Braingaze (2) · Chang Gung Memorial Hospital (2) · Johns Hopkins University (2) · iPACES LLC (2) · Alexandra Hospital (1) · Centre Hospitalier Universitaire de Nice (1) · China Medical University, China (1) · Cognito Therapeutics, Inc. (1) · Fondazione Don Carlo Gnocchi ETS (1) · IRCCS Fondazione Stella Maris (1) · Indiana University (1) · Jinxuan Cheng (1) · National Research Center for Rehabilitation Technical Aids (1) · Rowan (1)
United States (13) · Italy (2) · Spain (2) · Taiwan (2) · Argentina (1) · Canada (1) · China (1) · France (1) · Japan (1) · Singapore (1) · South Korea (1) · Switzerland (1)
Cay Anderson-Hanley, PhD (3) · David Ziegler, PhD (2) · Kyrana Tsapkini, PhD (2) · Adam Gazzaley, MD/PhD (1) · Andy Liu, MD (1) · Bob Gillen, PhD (1) · Cameron K Perrin, M.S. (1) · Christine Walsh, PhD (1) · Cristina Polito (1) · David A Ziegler, PhD (1) · Huei-Ling Chiu (1) · I-Ching Chuan, Ph.D (1) · Joseph M Gullett, Ph.D. (1)
PMID 30200183, PMID 30233154, PMID 22261206, PMID 27337738, PMID 29780318, PMID 30258975, PMID 33031971, PMID 34875098, PMID 37287321, PMID 42831056
R01AG076668 (1), R01DC014475 (1), R41AG053120 (1), R61AG080528 (1), R61AG083503 (1)