18 active not recruiting. 18 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 18 | Active not recruiting 18 |
| Phase 2 | 7 | Active not recruiting 7 |
Follow Lung Diseases, Obstructive: new trials by email Literature Review of Lung Diseases, Obstructive trials Research Report on Lung Diseases, Obstructive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Phase Ib Clinical Trial of the XH-S004 Tablet in Patients With Chronic Obstructive Pulmonary Disease (COPD) to Evaluate Its Safety, Tolerability, Pharmacokinetic Characteristics and Pharmacodynamic Characteristics After Multiple Administrations XH-S004 20 mg, 40 mg or 60 mg, Placebo - Chronic Obstructive Pulmonary Disease | Phase 1 | Active not recruiting | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 81 | 2025-07-15 | 2026-09-25 |
| A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD INCA034176 - Chronic Graft-versus-host-disease | Phase 1 / Phase 2 | Active not recruiting | Incyte Corporation | 32 | 2025-06-25 | 2026-08-10 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Immunogenicity of APG777 in Adults With Asthma APG777, Placebo - Asthma | Phase 1 | Active not recruiting | Apogee Therapeutics, Inc. | 31 | 2025-03-27 | 2026-10-13 |
| A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate Asthma AMG 691, Placebo - Asthma | Phase 1 | Active not recruiting | Amgen | 21 | 2024-10-16 | 2026-10-30 |
| Comparison of Bronchodilator Response From Three Different Aerosol Delivery Methods in Patients With COPD Using Hyperpolarized Xe 129 MRI Ventilation Imaging Albuterol Sulfate, 2.5 Mg/3 mL (0.083%) Inhalation Solution, Vibrating Mesh Nebulizer, Metered Dose Inhaler - Chronic Obstructive Pulmonary Disease | Phase 1 | Active not recruiting | Polarean, Inc. | 6 | 2024-03-19 | 2026-10-27 |
| TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD)) TDI01 suspension - GVHD, Chronic | Phase 1 / Phase 2 | Active not recruiting | Beijing Tide Pharmaceutical Co., Ltd | 60 | 2024-02-06 | 2025-09-26 |
| A Study to Investigate GB-0895 in Adults With Mild to Moderate Asthma or COPD GB-0895 (SC), Placebo (SC) - Asthma, COPD (Chronic Obstructive Pulmonary Disease) | Phase 1 | Active not recruiting | Generate Biomedicines | 156 | 2023-12-12 | 2025-11-05 |
| Intracerebral Transplantation of Autologous MSC Combined With Scaffold Product for Chronic Intracerebral Hemorrhage HUFF-01 - Intracerebral Hemorrhage | Phase 1 / Phase 2 | Active not recruiting | Hokkaido University Hospital | 8 | 2023-12-01 | 2026-10-15 |
| A Study for GSK3862995B in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease GSK3862995B, Placebo - Pulmonary Disease, Chronic Obstructive | Phase 1 | Active not recruiting | GlaxoSmithKline | 127 | 2023-11-27 | 2026-05-29 |
| Study to Assess the Safety of DERMASEAL for Diabetic Foot Ulcers DERMASEAL, Plasma Film, Standard of Care - Foot Ulcer, Diabetic | Phase 1 | Active not recruiting | Vitruvian Medical Devices, Inc. | 26 | 2022-10-03 | 2024-12-27 |
| Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily Maintenance Inhalers Adherence to symptom driven budesonide/formoterol as compared to adherence to maintenance ICS and symptom-driven SABA - Asthma, Nonadherence, Medication | Phase 1 / Phase 2 | Active not recruiting | Washington University School of Medicine | 60 | 2021-12-16 | 2026-08-19 |
| A Study of TQ05105 in Patients With Chronic Graft Versus Host Disease TQ05105 Tablet - Chronic Graft Versus Host Disease | Phase 1 / Phase 2 | Active not recruiting | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 45 | 2021-06-25 | 2025-12-03 |
| Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease Leflunomide - Chronic Graft Versus Host Disease, Steroid Refractory Graft Versus Host Disease | Phase 1 | Active not recruiting | City of Hope Medical Center | 18 | 2020-09-14 | 2026-10-19 |
| Wound Healing Endpoint and Recurrence Epiceram Skin Barrier Function, Vaseline Petroleum Jelly - Chronic Wound, Burn Wound | Phase 1 / Phase 2 | Active not recruiting | Sashwati Roy | 100 | 2019-01-08 | 2025-09-26 |
| Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation MPH966 - Chronic Graft vs Host Disease, Chronic Graft-Versus-Host Disease | Phase 1 / Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 14 | 2016-04-28 | 2026-10-16 |
| Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease Treg-enriched infusion, Interleukin-2 - Chronic Graft Versus Host Disease, Chronic GVHD | Phase 1 | Active not recruiting | Dana-Farber Cancer Institute | 25 | 2013-11-01 | 2026-02-05 |
| Vitamin D Supplementation During Pregnancy for Prevention of Asthma in Childhood Cholecalciferol D3, Placebo tablet - Asthma | Phase 1 | Active not recruiting | Copenhagen Studies on Asthma in Childhood | 600 | 2009-03-01 | 2026-03-19 |
| Fish Oil Supplementation During Pregnancy for Prevention of Asthma, Eczema and Allergies in Childhood n-3 fatty acid, olive oil - Asthma, Eczema | Phase 1 | Active not recruiting | Copenhagen Studies on Asthma in Childhood | 800 | 2008-11-26 | 2026-06-05 |
Bronchiolitis Obliterans Syndrome (9) · Asthma (6) · Pulmonary Disease, Chronic Obstructive (4) · Diabetic Foot (2) · Eczema (2) · Hypersensitivity (2) · Burns (1) · Cerebral Hemorrhage (1) · Diabetes Mellitus (1) · Infections (1) · Medication Adherence (1) · Pressure Ulcer (1) · Respiratory Sounds (1) · Wounds and Injuries (1)
Lung Diseases (18) · Respiratory Tract Diseases (18) · Bronchial Diseases (15) · Immune System Diseases (15) · Bronchiolitis (9) · Bronchiolitis Obliterans (9) · Bronchitis (9) · Graft vs Host Disease (9) · Organizing Pneumonia (9) · Hypersensitivity, Immediate (6) · Pathological Conditions, Signs and Symptoms (6) · Respiratory Hypersensitivity (6) · Pathologic Processes (5) · Chronic Disease (4)
Albuterol (1) · Fatty Acids, Omega-3 (1) · Formoterol Fumarate (1) · Interleukin-2 (1) · Leflunomide (1) · Metered Dose Inhalers (1) · Olive Oil (1) · Petroleum (1) · Standard of Care (1) · axatilimab (1)
Copenhagen Studies on Asthma in Childhood (2) · Amgen (1) · Apogee Therapeutics, Inc. (1) · Beijing Tide Pharmaceutical Co., Ltd (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · City of Hope Medical Center (1) · Dana-Farber Cancer Institute (1) · Generate Biomedicines (1) · GlaxoSmithKline (1) · Hokkaido University Hospital (1) · Incyte Corporation (1) · National Cancer Institute (NCI) (1) · Polarean, Inc. (1) · Sashwati Roy (1) · Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. (1)
United States (11) · China (4) · United Kingdom (4) · Denmark (2) · Germany (2) · Australia (1) · Belgium (1) · Canada (1) · Japan (1)
Amandeep Salhotra (1) · Jaime Mata, PhD (1) · James G Krings, MD MSc (1) · John Koreth, MBBS, DPhil (1) · Najla El Jurdi, M.D. (1) · Sashwati Roy, PhD (1)
PMID 36184023, PMID 26813208, PMID 28029926, PMID 29077711, PMID 30181143, PMID 30418579, PMID 31381020, PMID 32091548, PMID 33289844, PMID 33653805, PMID 34398099, PMID 34927195, PMID 35105560, PMID 35475885, PMID 36471430, PMID 37380711, PMID 37696621, PMID 38072183, PMID 38569788, PMID 39077939, PMID 39196551, PMID 40009501, PMID 40865727, PMID 41422501, PMID 41771441, PMID 42149595, PMID 42463642
2023 (2), 2008 (1), KL2TR002346 (1), R01CA183559 (1), UL1TR002345 (1)