9 completed, 5 recruiting, 3 enrolling by invitation, 3 not yet recruiting. 12 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 4, Recruiting 4, Enrolling by invitation 2, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 1 | Enrolling by invitation 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Lumbar Degenerative Disease: new trials by email Literature Review of Lumbar Degenerative Disease trials Research Report on Lumbar Degenerative Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Osteoporotic Medications on Vertebral Bone Quality Score Abaloparatide - Lumbar Degenerative Disease | Phase 2 | Enrolling by invitation | State University of New York at Buffalo | 60 | 2026-06-18 | 2026-07-23 |
| Effect of Obesity Phenotype on Intraabdominal Pressure and Bleeding in Major Lumbar Spinal Surgery Intraabdominal Pressure Measurement via Urinary Bladder Catheter, Total Intravenous Anesthesia (TIVA) - Lumbar Spinal Stenosis, Lumbar Degenerative Disease | Not yet recruiting | Marmara University Pendik Training and Research Hospital | 90 | 2026-06-15 | 2026-07-07 | |
| Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery II Multimodal physiological reserve optimizing prehabilitation program, Usual Care - Spine Degeneration, Lumbar Degenerative Disease | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 248 | 2026-04-15 | 2026-07-27 |
| Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery Unilateral Biportal Endoscopic Surgery - Lumbar Disc Herniation, Lumbar Spinal Stenosis | Not applicable | Recruiting | Fan Zhang | 80 | 2026-02-05 | 2026-09-23 |
| Physiotherapy and Osteopathic Treatment for Pain in the Cervical and Lumbar Spine and Temporomandibular Joints General Osteopathic Treatment, Visceral Therapy, Magnetic field therapy - Disc Degenerative Disease, Spine Degeneration | Not applicable | Enrolling by invitation | Poznan University of Physical Education | 300 | 2026-02-01 | 2026-09-21 |
| Comparison of Endoscopic Lumbar Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion(MIS-TLIF) for Degenerative Lumbar Spondylolisthesis Lumbar Endoscopic - Unilateral Laminotomy for Bilateral Decompression - Degenerative Lumbar Spondylolisthesis, Lumbar Degenerative Disease | Not applicable | Not yet recruiting | Queen Savang Vadhana Memorial Hospital, Thailand | 66 | 2025-05-01 | 2025-04-22 |
| Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain Midline Lumbar Interbody Fusion (MIDLIF), Minimally Invasive Transforaminal Lumbar Interbody Fusion (mini-TLIF) - Lower Back Pain Chronic, Lumbar Degenerative Disease | Not applicable | Recruiting | Copernicus Memorial Hospital | 100 | 2025-01-19 | 2026-04-15 |
| Erector Spinae Plan Block (ESPB) with Dexmedetomidine and Dexamethasone in Lumbar Spine Fusion Adjuvant analgesia, Control (Standard treatment) - Lumbar Degenerative Disease | Phase 4 | Not yet recruiting | University of Southern California | 46 | 2024-11-01 | 2024-10-26 |
| Study on Topping-off Technique for Treating LDD Topping-off Group, Fusion Group - Lumbar Degenerative Disease | Not applicable | Recruiting | Qianfoshan Hospital | 100 | 2024-10-18 | 2024-10-21 |
| Multivariate Analysis and Risk Factors Were Used to Predict the Short-term Postoperative Pain of Degenerative Lumbar Spine Magnetic Resonance Imaging with Contrast - Lumbar Disc Herniation, Lumbar Degenerative Disease | Completed | Hao Liu | 936 | 2024-09-20 | 2024-10-08 | |
| Multivariate Analysis and Machine Learning Model Risk Prediction of Recurrent Pain After PLIF Surgery for Degenerative Lumbar Spine Disease At Long-term Follow-up MRI with Eovist - Lumbar Disc Herniation, Lumbar Degenerative Disease | Completed | Hao Liu | 452 | 2024-09-20 | 2024-10-02 | |
| CONDUIT™ Anterior Lumbar Interbody Fusion (ALIF) Cage System in Lumbar Degenerative Disease CONDUIT - Lumbar Degenerative Disease | Recruiting | University College Dublin | 35 | 2024-06-28 | 2025-04-23 | |
| Comparison of Clinical Effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in Patients With Lumbar Disc Herniation FELD (Full-Endoscopic Lumbar Discectomy), comprising IELD and TELD as anatomical subgroups, Microdiscectomy - Lumbar Degenerative Disease, Lumbar Radiculopathy | Not applicable | Completed | University of Opole | 200 | 2024-03-01 | 2026-06-10 |
| Unilateral Biportal Endoscopy Lumbar Interbody Fusion (ULIF) Versus Posterior Lumbar Interbody Fusion (PLIF) in Management of Single Level Lumbar Degenerative Disease: A Retrospective Study Lumbar Degenerative Disease | Completed | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 140 | 2022-11-01 | 2024-07-17 | |
| CONDUIT vs. PEEK Cages Cougar LS/Syncage ALIF or CONDUIT LLIF/ALIF cage - Lumbar Degenerative Disease | Not applicable | Completed | University of Pennsylvania | 32 | 2021-03-13 | 2026-09-24 |
| The Study of INTRA Spine Non Fusion Technique in the Treatment of Lumbar Degenerative Disease Non-fusion group, Fusion group - Lumbar Degenerative Disease | Not applicable | Enrolling by invitation | Qianfoshan Hospital | 60 | 2020-01-01 | 2025-01-29 |
| Effects of Health Education for Patients Received Minimally Invasive Lumbar Spinal Surgery Perioperative Rehabilitation - Low Back Pain, Lumbar Degenerative Disease | Not applicable | Unknown | Taipei Medical University Shuang Ho Hospital | 100 | 2019-04-25 | 2019-10-09 |
| ISOVUE Comparative Trial ISOVUE 300 Observation, ISOVUE 300 Feedback - Lumbar Degenerative Disease, Lumbar Degenerative Disc Disease | Not applicable | Completed | Rush University Medical Center | 56 | 2019-04-11 | 2026-01-23 |
| Effectiveness of Implementing Shared Decision-Making on Quality of Care Among Patients With Lumbar Degenerative Diseases. Shared decision making support tool - Lumbar Degenerative Disease, Shared Decision Making | Not applicable | Completed | Taipei Medical University | 130 | 2018-09-26 | 2020-02-19 |
| Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery Lumbar Degenerative Disease | Completed | Mayo Clinic | 103 | 2009-03-01 | 2022-04-15 |
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Intervertebral Disc Displacement (5) · Intervertebral Disc Degeneration (4) · Spinal Stenosis (3) · Low Back Pain (2) · Sarcopenia (2) · Agnosia (1) · Back Pain (1) · Intervertebral disc disease (1) · Intra-Abdominal Hypertension (1) · Nausea (1) · Obesity (1) · Osteoporosis (1) · Postoperative Nausea and Vomiting (1) · Radiculopathy (1) · Sciatica (1)
Bone Diseases (11) · Musculoskeletal Diseases (11) · Pathological Conditions, Signs and Symptoms (10) · Spinal Diseases (10) · Signs and Symptoms (8) · Neurologic Manifestations (7) · Hernia (5) · Nervous System Diseases (5) · Pathological Conditions, Anatomical (5) · Pain (4) · Atrophy (2) · Back Pain (2) · Muscular Atrophy (2) · Muscular Diseases (2) · Neuromuscular Diseases (2)
Magnetic Resonance Spectroscopy (2) · Contrast Media (1) · Magnetic Field Therapy (1) · Urinary Diversion (1) · abaloparatide (1) · gadolinium ethoxybenzyl DTPA (1)
Hao Liu (2) · Qianfoshan Hospital (2) · Copernicus Memorial Hospital (1) · Fan Zhang (1) · Marmara University Pendik Training and Research Hospital (1) · Mayo Clinic (1) · Poznan University of Physical Education (1) · Queen Savang Vadhana Memorial Hospital, Thailand (1) · Rush University Medical Center (1) · State University of New York at Buffalo (1) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (1) · Taipei Medical University (1) · Taipei Medical University Shuang Ho Hospital (1) · University College Dublin (1) · University of Opole (1)
China (7) · United States (4) · Poland (3) · Taiwan (2) · Ireland (1) · Spain (1) · Thailand (1)
Hao-Xuan Zhang, Ph.D/MD (2) · Ahmad Nassr, M.D. (1) · Heng-Wei Liu, Doctor (1) · Joseph Butler, PhD (1) · Kajetan Latka, PhD (1)