25 completed, 8 unknown, 3 not yet recruiting, 3 recruiting. 15 Not applicable, 4 Phase 3, 4 Phase 4, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 8, Unknown 3, Recruiting 2, Terminated 2 |
| Phase 3 | 4 | Completed 3, Recruiting 1 |
| Phase 4 | 4 | Completed 3, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Not yet recruiting 1 |
Follow Lower Respiratory Tract Infection: new trials by email Literature Review of Lower Respiratory Tract Infection trials Research Report on Lower Respiratory Tract Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial of V175 and V175A in Healthy Adults V175, V175A, Control Vaccine - Lower Respiratory Tract Infection | Phase 1 | Not yet recruiting | Merck Sharp & Dohme LLC | 564 | 2026-10-27 | 2026-10-02 |
| Clinical Predictors of Severity in Pediatric Community-Acquired Pneumonia at Assiut University Children's Hospital Assessment of Pneumonia Severity - Community-Acquired Pneumonia, Pediatric Pneumonia | Not yet recruiting | Assiut University | 67 | 2025-12-01 | 2025-12-12 | |
| Recurrent Pneumonia in Children Pneumonia, Lower Respiratory Tract Infection | Unknown | Assiut University | 53 | 2025-01-01 | 2024-09-04 | |
| The Effect of a Family-Centered Care Approach on Infants Receiving High-Flow Nasal Oxygen Therapy maintenance training - Lower Respiratory Tract Infection | Completed | Ankara Etlik City Hospital | 60 | 2024-12-01 | 2025-09-19 | |
| Reducing Overuse of Antibiotics With Decision Support ED Clinical Decision Support (CDS-ED), Transitions Clinical Decision Support (CDS-Tr) - Lower Respiratory Tract Infection, Pneumonia | Not applicable | Recruiting | Vanderbilt University Medical Center | 2800 | 2024-11-12 | 2026-01-22 |
| CRP and Lung Ultrasound in Respiratory Evaluation Lung ultrasound, C-Reactive Protein Test - Primary Health Care, Lower Respiratory Tract Infection | Not yet recruiting | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 202 | 2024-06-01 | 2024-04-30 | |
| A Study Evaluating the Use of ResAppDx v2.0 as an Aid to Diagnose Respiratory Disease in Paediatric Patients in an Emergency Department ResAppDx v.20 - Croup, Bronchiolitis | Completed | ResApp Health Limited | 75 | 2024-01-01 | 2024-03-04 | |
| The Effect of Focused Lung Ultrasonography on Antibiotic Prescribing in General Practice Focused lung ultrasound (FLUS), Usual Care - Lower Respiratory Tract Infection, Community Acquired Pneumonia | Not applicable | Completed | Aalborg University | 391 | 2023-11-03 | 2024-11-29 |
| Safe, Effective and Cost-Effective Oxygen Saturation Targets for Children and Adolescents With Respiratory Distress: a Randomized Controlled Trial Oxygen saturation threshold - Bronchiolitis, Lower Respiratory Tract Infection | Not applicable | Completed | Spaarne Gasthuis | 566 | 2023-09-04 | 2026-07-14 |
| The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL) MeMed BV test - Lower Respiratory Tract Infection | Not applicable | Recruiting | MeMed Diagnostics Ltd. | 1316 | 2023-01-31 | 2026-10-09 |
| Procalcitonin and Lung Ultrasonography Guided Antibiotherapy in Emergency Departments The PLUS algorithm, Usual care - Lower Respiratory Tract Infection | Not applicable | Completed | Dr Boillat-Blanco Noemie | 1407 | 2022-12-05 | 2026-04-24 |
| Antiviral Activity of Oral Probiotics Streptococcus salivarius K12 Powder 1 Billion colony forming units /g), Streptococcus salivarius K12 Powder (1 Billion colony forming units /g) with a prebiotic included, Streptococcus salivarius M18 Powder (1 Billion colony forming units /g) - Lower Respiratory Tract Infection, Upper Respiratory Tract Infection | Not applicable | Unknown | John Hale | 20 | 2022-05-23 | 2022-05-13 |
| A Low-Resource Oxygen Blender Prototype for Use in Modified Bubble CPAP Circuits Low-Resource Oxygen Blender - Respiratory Distress Syndrome, Lower Respiratory Tract Infection | Not applicable | Completed | University of Minnesota | 33 | 2022-03-26 | 2024-04-15 |
| Evaluate the Safety and Efficacy of Nirsevimab in Healthy Preterm and Term Infants in China Nirsevimab, Placebo - Lower Respiratory Tract Infection | Phase 3 | Completed | AstraZeneca | 800 | 2021-11-24 | 2026-10-15 |
| Bronchoscopy in Lower Respiratory Tract Infection in Respiratory Intensive Care Unit fiberoptic bronchoscopy - Lower Respiratory Tract Infection | Unknown | Assiut University | 100 | 2021-05-01 | 2020-05-11 | |
| RASCALS: Rapid Assay for Sick Children With Acute Lung Infection Study Rapid Pathogen Detection - Lower Respiratory Tract Infection, Ventilator Associated Pneumonia | Unknown | Cambridge University Hospitals NHS Foundation Trust | 250 | 2020-06-06 | 2021-10-20 | |
| Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study DAS181, Placebo, DAS181 COVID-19 - Lower Respiratory Tract Infection, Parainfluenza | Phase 3 | Recruiting | Ansun Biopharma, Inc. | 274 | 2019-05-23 | 2026-06-23 |
| Approach for Optimizing Meropenem Therapy in Intubated and Mechanically-Ventilated, Adult Patients With Severe Gram-Negative Lower Respiratory Tract Infection MON4STRAT Strategy, Control group - Lower Respiratory Tract Infection | Not applicable | Terminated | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 7 | 2019-02-18 | 2020-02-17 |
| Flublok v. Standard Dose Vaccine Effectiveness Among Kaiser Permanente Northern California Adults 18-64 Years Flublok Quadrivalent, Standard Dose Inactivated Influenza Vaccine (SD-IIV) - Influenza, Pneumonia | Completed | Kaiser Permanente | 2776278 | 2018-09-16 | 2025-04-08 | |
| The Norwegian Antibiotics for Pneumonia in Children Study Amoxicillin, Placebos - Pneumonia Childhood, Lower Respiratory Tract Infection | Phase 4 | Unknown | Oslo University Hospital | 884 | 2018-03-07 | 2018-04-11 |
Showing 20 of 41. Sign in to see all of them.
Pneumonia (13) · Respiratory Tract Infections (8) · Bronchiolitis (4) · Influenza, Human (4) · Community-Acquired Pneumonia (3) · Pulmonary Disease, Chronic Obstructive (3) · Asthma (2) · Bronchitis (2) · COVID-19 (2) · Croup (2) · Infections (2) · Otitis Media (2) · Body Weight (1) · Bronchial Hyperreactivity (1) · Bronchiolitis, Viral (1)
Respiratory Tract Diseases (26) · Infections (25) · Lung Diseases (17) · Respiratory Tract Infections (16) · Pathological Conditions, Signs and Symptoms (10) · Pathologic Processes (8) · Virus Diseases (8) · Bronchial Diseases (7) · Disease Attributes (7) · Lung Diseases, Obstructive (7) · RNA Virus Infections (7) · Bronchitis (5) · Orthomyxoviridae Infections (4) · Otorhinolaryngologic Diseases (4) · Pneumonia (4)
13-valent pneumococcal vaccine (1) · Algorithms (1) · Amoxicillin (1) · Azithromycin (1) · Clarithromycin (1) · Control Groups (1) · Early Intervention, Educational (1) · Oseltamivir (1) · PHiD-CV vaccine (1) · Sodium Chloride (1) · Standard of Care (1) · Suspensions (1) · dornase alfa (1) · nirsevimab (1) · oplunofusp (1)
Assiut University (3) · MeMed Diagnostics Ltd. (2) · ResApp Health Limited (2) · ADMA Biologics, Inc. (1) · Aalborg University (1) · Abbott (1) · Ankara Etlik City Hospital (1) · Ansun Biopharma, Inc. (1) · AstraZeneca (1) · Bin Cao (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Chinese University of Hong Kong (1) · Dr Boillat-Blanco Noemie (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal (1)
United States (8) · China (4) · Israel (4) · Australia (3) · United Kingdom (3) · Canada (2) · Netherlands (2) · Switzerland (2) · Thailand (2) · Bangladesh (1) · Belgium (1) · Cambodia (1) · Denmark (1) · France (1) · Hong Kong (1)
Ali A. Hasan, ass. prof. (1) · Amanda J Leach, PhD (1) · Andrew Wu, MD, MPH (1) · Annmeie LM Boehmer, MD, PhD (1) · Asmaa O. Ahmed, ass. prof (1) · Beat Mueller, Prof. (1) · Benjamin J Tarrant, B.Physio (1) · Bosco Paes, MD, FRCPC (1) · Derek J Williams, MD, MPH (1) · Dorothy Baker, PhD (1) · Hoda A. Makhlouf, Prof (1) · Ian Mitchell, MB, FRCPC (1) · John D Hale, PhD (1) · John R Tagg, PhD (1)
PMID 11821511, PMID 12226033, PMID 12588210, PMID 14987884, PMID 16107222, PMID 16603606, PMID 16757722, PMID 16805922, PMID 20222964, PMID 20299634, PMID 20529344, PMID 21343842, PMID 22203430, PMID 22546928, PMID 23369797, PMID 23582723, PMID 23861694, PMID 23901082, PMID 23989104, PMID 24268590, PMID 24799541, PMID 25520333, PMID 25785720, PMID 25788164, PMID 26237402, PMID 26343252, PMID 26719947, PMID 26780032, PMID 26791364, PMID 26859559, PMID 27331856, PMID 27552617, PMID 27649365, PMID 28012942, PMID 28097633, PMID 28105526, PMID 28403044, PMID 28535933, PMID 28604925, PMID 28904072, PMID 28953024, PMID 29557081, PMID 29781385, PMID 30137509, PMID 30409683, PMID 30517603, PMID 30578007, PMID 30985509, PMID 31229593, PMID 31232615
2018 (2), 2023 (1), R01AG030575 (1), U01IP000127 (1)