10 completed, 4 terminated, 2 recruiting, 2 unknown. 6 Phase 3, 3 Not applicable, 3 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 2, Recruiting 2, Terminated 2 |
| Not applicable | 3 | Completed 2, Terminated 1 |
| Phase 4 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Croup: new trials by email Literature Review of Croup trials Research Report on Croup
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma Cholecalciferol D3, Olive oil - Asthma, Respiratory Tract Infections | Phase 3 | Recruiting | Professor Klaus Bønnelykke | 2000 | 2024-12-20 | 2025-09-30 |
| Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma n-3 fatty acid, Rape seed oil - Asthma, Respiratory Tract Infections | Phase 3 | Recruiting | Professor Klaus Bønnelykke | 2000 | 2024-12-20 | 2025-09-30 |
| Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup oral dexamethasone, intramuscular dexamethasone - Laryngotracheobronchitis, Croup | Not applicable | Completed | Arooj Khan | 200 | 2024-10-01 | 2026-01-29 |
| Croup Dosing Study 0.15 mg/kg dexamethasone - Croup | Phase 3 | Completed | University of Manitoba | 50 | 2024-06-05 | 2025-09-08 |
| A Study Evaluating the Use of ResAppDx v2.0 as an Aid to Diagnose Respiratory Disease in Paediatric Patients in an Emergency Department ResAppDx v.20 - Croup, Bronchiolitis | Completed | ResApp Health Limited | 75 | 2024-01-01 | 2024-03-04 | |
| Telemedicine in the Generals Practitioners Office Telemedicine - Respiratory Distress Syndrome, Pneumonia | Unknown | Rijnstate Hospital | 40 | 2019-12-01 | 2019-11-19 | |
| Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup Dexamethasone IV for PO, Dexamethasone crushed tablets - Asthma, Croup | Phase 4 | Terminated | Vanderbilt University Medical Center | 40 | 2018-10-23 | 2021-11-08 |
| Diagnosing Respiratory Disease in Children Using Cough Sounds 2 Recordings of Infants and Children's Cough Sounds - Pneumonia, Bronchiolitis | Completed | ResApp Health Limited | 1470 | 2018-01-05 | 2018-11-08 | |
| Diagnosing Respiratory Disease in Children Using Cough Sounds Recording of Infants and Children's Cough Sounds - Pneumonia, Bronchiolitis | Completed | ResApp Health Limited | 1245 | 2016-12-01 | 2018-01-05 | |
| Impact of Cold Air Exposure on Croup Symptoms Outdoor cold air exposure - Croup | Not applicable | Completed | Pediatric Clinical Research Platform | 118 | 2016-11-01 | 2023-01-11 |
| The Effect and Safety of Low Dose Nebulized Epinephrine in Croup conventional dose epinephrine, low dose epinephrine - Croup, Epinephrine, Administration, Inhalation | Phase 4 | Unknown | Seoul National University Hospital | 84 | 2016-01-01 | 2018-01-09 |
| Non Interventional Study (NIS) Regarding the Application of Ectoin Mund- & Rachenspray in Patients With Acute Laryngitis and/or Acute Pharyngitis Acute Pharyngitis, Acute Laryngitis | Completed | Bitop AG | 95 | 2014-02-01 | 2015-01-09 | |
| Management of Recurrent Croup Fluticasone, Prednisolone IF needed - Croup | Phase 3 | Terminated | University of Michigan | 10 | 2012-09-01 | 2017-11-13 |
| Efficacy of Nebulized Beclomethasone Dipropionate (BDP) in the Treatment of Moderate Croup beclomethasone dipropionate suspension for nebulisation 800 mcg/2 ml, Placebo solution for nebulisation 2 ml - Croup | Phase 3 | Terminated | Chiesi Farmaceutici S.p.A. | 6 | 2010-04-01 | 2011-04-29 |
| Community Care for Croup (RCT) Prednisone, Dexamethasone - Croup | Phase 4 | Completed | Washington University School of Medicine | 87 | 2009-10-01 | 2014-09-15 |
| Comparing Different Ways of Delivering Humidity to Children With Croup nebulized humidity - Croup | Phase 2 | Completed | The Hospital for Sick Children | 129 | 2001-09-01 | 2013-08-02 |
| A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup mailing of printed educational materials, a combination of interactive educational meetings, educational outreach visits, and reminders, identification of local opinion leaders and establishment of local consensus processes - Croup | Not applicable | Terminated | Canadian Institutes of Health Research (CIHR) | 2000-09-01 | 2005-11-29 | |
| A Trial of Point of Care Information in Ambulatory Pediatrics Electronic point-of-care delivery system - Acute Otitis Media, Allergic Rhinitis | Phase 3 | Completed | University of Washington | 44 | 1999-11-01 | 2006-08-29 |
Asthma (5) · Bronchiolitis (5) · Pneumonia (4) · Pulmonary Disease, Chronic Obstructive (3) · Respiratory Tract Infections (3) · Eczema (2) · Fractures, Bone (2) · Hypersensitivity (2) · Infections (2) · Mental Disorders (2) · Respiratory Sounds (2) · Bronchial Hyperreactivity (1) · Constipation (1) · Dyspnea (1)
Laryngeal Diseases (18) · Otorhinolaryngologic Diseases (18) · Respiratory Tract Diseases (18) · Laryngitis (17) · Bronchial Diseases (8) · Lung Diseases (8) · Lung Diseases, Obstructive (8) · Pathological Conditions, Signs and Symptoms (8) · Hypersensitivity, Immediate (6) · Immune System Diseases (6) · Infections (6) · Respiratory Hypersensitivity (6) · Bronchitis (5) · Respiratory Tract Infections (5) · Hypersensitivity (4)
Dexamethasone (4) · Calcium Dobesilate (1) · Epinephrine (1) · Fatty Acids, Omega-3 (1) · Fluticasone (1) · Olive Oil (1) · Prednisone (1)
ResApp Health Limited (3) · Professor Klaus Bønnelykke (2) · Arooj Khan (1) · Bitop AG (1) · Canadian Institutes of Health Research (CIHR) (1) · Chiesi Farmaceutici S.p.A. (1) · Pediatric Clinical Research Platform (1) · Rijnstate Hospital (1) · Seoul National University Hospital (1) · The Hospital for Sick Children (1) · University of Manitoba (1) · University of Michigan (1) · University of Washington (1) · Vanderbilt University Medical Center (1) · Washington University School of Medicine (1)
United States (6) · Canada (2) · Denmark (2) · Germany (1) · Italy (1) · Pakistan (1) · South Korea (1) · United Kingdom (1)
Bo Chawes, PhD (2) · Peter P Moschovis, MD, MPH (2) · Alex Aregbesola, MD, PhD (1) · David J Brown, MD (1) · David W Johnson, MD (1) · Dennis Scolnik, MD (1) · Donald Arnold, MD, MPH (1) · Jane M Garbutt, MB, ChB (1) · Johan Siebert, MD (1) · Margreet Wessels, MD, PhD (1) · Robert L Davis, MD, MPH (1) · Terry Klassen, MD, MSc (1)
PMID 39740942, PMID 16537737, PMID 16855994, PMID 24092872, PMID 25263284, PMID 26319919, PMID 27139290, PMID 27244794, PMID 28858086, PMID 29763253, PMID 30878411, PMID 31416827, PMID 31442871, PMID 36596609, PMID 37525974, PMID 42249465
2016 (1)