17 completed, 4 terminated, 2 unknown, 1 active not recruiting. 15 Not applicable, 5 Phase 4, 3 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 10, Terminated 2, Unknown 2, Recruiting 1 |
| Phase 4 | 5 | Completed 4, Terminated 1 |
| Phase 3 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Withdrawn 1 |
Follow Bronchiolitis, Viral: new trials by email Literature Review of Bronchiolitis, Viral trials Research Report on Bronchiolitis, Viral
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Internal Jugular Vein Respiratory Variability as a Marker of Disease Severity in Infant Bronchiolitis Point-of-Care Ultrasonography - Acute Bronchiolitis, Viral Bronchiolitis | Not yet recruiting | Eskisehir Osmangazi University | 120 | 2026-09-01 | 2026-08-21 | |
| Effectiveness of Immunization in Preventing Severe Acute Respiratory Infection RSV in Children Under 6 Months in Bogotá RSVpreF vaccine (Abrysvo) and Nirsevimab (Beyfortus) or unexposed - Respiratory Syncytial Virus Infections, Severe Acute Respiratory Infection | Active not recruiting | Bogotá District Health Secretariat | 1097 | 2026-01-01 | 2026-08-06 | |
| Reducing Overuse of Antibiotics With Decision Support ED Clinical Decision Support (CDS-ED), Transitions Clinical Decision Support (CDS-Tr) - Lower Respiratory Tract Infection, Pneumonia | Not applicable | Recruiting | Vanderbilt University Medical Center | 2800 | 2024-11-12 | 2026-01-22 |
| Effectiveness of Nirsevimab in Children Hospitalised With RSV Bronchiolitis No intervention required by the protocol - Bronchiolitis, Viral | Completed | Centre Hospitalier Intercommunal Creteil | 1140 | 2023-10-15 | 2025-08-29 | |
| SWISH Trial (Strategies for Weaning Infants on Supportive High Flow) High flow nasal cannula support - Respiratory Disease, Bronchiolitis, Viral | Not applicable | Completed | Cardiff and Vale University Health Board | 20 | 2023-10-06 | 2025-06-08 |
| Pediatric Helmet CPAP Pilot Study Helmet CPAP - Bronchiolitis, Viral, Pneumonia, Viral | Not applicable | Terminated | Columbia University | 5 | 2021-08-07 | 2024-07-29 |
| Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With Bronchiolitis Magnesium Sulfate - Bronchiolitis, Viral | Phase 2 / Phase 3 | Withdrawn | University of Louisville | 2021-07-21 | 2026-05-11 | |
| Prone Position in Acute Bronchiolitis Supine position (SP), Prone position (PP) - Acute Viral Bronchiolitis | Not applicable | Completed | Hospices Civils de Lyon | 452 | 2021-01-13 | 2026-06-25 |
| Work of Breathing in Bronchiolitis Under Non-invasive Ventilation Esogastric pressures measurement - Severe Viral Bronchiolitis | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 20 | 2021-01-05 | 2026-03-09 |
| Nasal Bubble Continuous Positive Airway Pressure in Reducing Respiratory Distress in Children With Bronchiolitis nasal continuous positive airway pressure - Bronchiolitis Acute Viral, Bronchiolitis | Not applicable | Unknown | ameer asadullah gull | 96 | 2020-09-06 | 2021-08-04 |
| Steroid Use in Non-RSV Bronchiolitis Placebos, Dexamethasone Oral - Bronchiolitis, Viral | Phase 4 | Terminated | Allison Williams | 3 | 2020-02-03 | 2023-03-21 |
| Efficacy and Safety of Curosurf® in Patients Invasively Ventilated for Severe Bronchiolitis Under 12 Months of Age Curosurf 80Mg/Ml Intratracheal Suspension, Ambient Air - Bronchiolitis, Viral | Phase 3 | Terminated | Azienda Ospedaliera Universitaria Integrata Verona | 9 | 2019-01-09 | 2021-04-15 |
| High Flow Oxygen Therapy vs Standard Care in Infants With Viral Bronchiolitis High flow humidified oxygen therapy - Bronchiolitis, Viral | Not applicable | Terminated | Chris Hani Baragwanath Academic Hospital | 28 | 2017-06-01 | 2019-07-24 |
| Nasal and Bronchial Absorption Sampling in RSV Bronchiolitis Nasal and Bronchial Sampling - Bronchiolitis, Bronchiolitis, Viral | Not applicable | Completed | Imperial College Healthcare NHS Trust | 152 | 2015-10-02 | 2019-11-12 |
| Chest Physiotherapy in Infants Between 0 and 12 Months Old With Acute Bronchiolitis SRV(+) Prolonged slow expiration+provoked coughing, Manual chest wall vibration, Standard Therapy - Bronchiolitis, Viral | Not applicable | Completed | Universidad del Desarrollo | 204 | 2015-03-01 | 2016-10-26 |
| Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis 3% Saline, 0.9% Normal Saline - Acute Viral Bronchiolitis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 778 | 2012-10-01 | 2014-07-28 |
| Home Oxygen Treatment of Childhood Acute Bronchiolitis Home oxygen therapy - Bronchiolitis, Viral, Home Nursing | Not applicable | Unknown | Soroka University Medical Center | 85 | 2012-10-01 | 2012-06-13 |
| Glucocorticoid Therapy Impact on the Inflammatory Response and Clinical Evolution in Patients With Severe Bronchiolitis Glucocorticoids, Placebo - Bronchiolitis, Viral | Phase 4 | Completed | Fundació Sant Joan de Déu | 94 | 2011-11-01 | 2015-10-08 |
| Hypertonic Saline for Acute Bronchiolitis Nebulized 3% saline, Nebulized 0.9% Normal Saline - Bronchiolitis, Viral, Saline Solution, Hypertonic | Phase 4 | Completed | Children's Hospital of Philadelphia | 62 | 2010-10-01 | 2014-08-19 |
| Effectiveness of Chest Physiotherapy in Infants With Acute Viral Bronchiolitis Chest physiotherapy - Conventional, Chest physiotherapy - actual techniques, 3-Airway suction - Viral Bronchiolitis | Not applicable | Completed | Hospital Sirio-Libanes | 33 | 2009-04-01 | 2012-08-30 |
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Bronchiolitis (9) · Respiratory Syncytial Virus Infections (3) · Respiratory Sounds (2) · Asthma (1) · Bronchial Diseases (1) · Lung Diseases, Obstructive (1) · Pneumonia (1) · Pneumonia, Bacterial (1) · Pneumonia, Viral (1) · Respiration Disorders (1) · Respiratory Insufficiency (1) · Respiratory Tract Diseases (1) · Respiratory Tract Infections (1) · Virus Diseases (1)
Bronchitis (27) · Infections (27) · Lung Diseases (27) · Bronchial Diseases (26) · Lung Diseases, Obstructive (26) · Respiratory Tract Diseases (26) · Respiratory Tract Infections (26) · Virus Diseases (26) · Bronchiolitis (18) · Mononegavirales Infections (3) · Paramyxoviridae Infections (3) · Pneumovirus Infections (3) · RNA Virus Infections (3) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2)
Saline Solution, Hypertonic (4) · Dexamethasone (3) · Saline Solution (3) · Sodium Chloride (3) · Inhalation (2) · Albuterol (1) · Calcium Dobesilate (1) · Continuous Positive Airway Pressure (1) · Epinephrine (1) · Fluid Therapy (1) · Glucocorticoids (1) · Glucose (1) · Magnesium Sulfate (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1)
Assistance Publique - Hôpitaux de Paris (3) · Allison Williams (1) · Azienda Ospedaliera Universitaria Integrata Verona (1) · Bnai Zion Medical Center (1) · Bogotá District Health Secretariat (1) · Cardiff and Vale University Health Board (1) · Centre Hospitalier Intercommunal Creteil (1) · Children's Hospital of Philadelphia (1) · Chris Hani Baragwanath Academic Hospital (1) · Columbia University (1) · Eskisehir Osmangazi University (1) · Fundació Sant Joan de Déu (1) · Hamad Medical Corporation (1) · Hospices Civils de Lyon (1) · Hospital Sirio-Libanes (1)
United States (6) · France (5) · Brazil (2) · United Kingdom (2) · Canada (1) · Chile (1) · Colombia (1) · Israel (1) · Italy (1) · Pakistan (1) · Qatar (1) · South Africa (1) · Thailand (1) · Turkey (Türkiye) (1)
Allison E Williams, MD (1) · Amir Kugelman, MD (1) · Brian Kuzik, MD (1) · Derek J Williams, MD, MPH (1) · Evelim LF Dantas Gomes, Master (1) · Howard Corneli, MD (1) · Hugo CD Souza, Ph.D. (1) · Jamaree Teeratakulpisarn, M.D. (1) · John W Berkenbosch, MD (1) · Joseph Zorc, MD, MSCE (1) · Khalid M. Al-Ansari, FRCPC,FAAP (1)
PMID 37010196, PMID 17652648, PMID 20646715, PMID 20927359, PMID 21073773, PMID 22499404, PMID 23260101, PMID 24271093, PMID 24862342, PMID 28586918, PMID 33077567, PMID 37097049, PMID 38986058, PMID 39521467, PMID 42307570