12 completed, 10 recruiting, 4 not yet recruiting, 1 active not recruiting. 19 Not applicable, 4 Phase 2, 2 Phase 3, 1 Phase 1.
Follow Knee Osteoarthritis (OA): new trials by email Literature Review of Knee Osteoarthritis (OA) trials Research Report on Knee Osteoarthritis (OA)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cross-Education From Unilateral Strength and Balance Training in Older Adults With Bilateral Knee Osteoarthritis 8-Week Unilateral Strength and Balance Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis, 8-Week Unilateral Balance Training Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis, 8-Week Unilateral Strength Training Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis - Knee Osteoarthritis (OA) | Not applicable | Not yet recruiting | University of Zagreb | 45 | 2026-09-01 | 2026-03-24 |
| Effect of Adding a Biceps Femoris Short Head Block to Adductor Canal Block for Analgesia After Total Knee Arthroplasty Ultrasound-Guided Adductor Canal Block, Ultrasound-Guided Biceps Femoris Short Head Block - Knee Osteoarthritis (OA), Postoperative Pain | Not applicable | Not yet recruiting | Antalya Training and Research Hospital | 122 | 2026-09-01 | 2026-09-04 |
| Manual Traction and Rehabilitation After Knee Replacement Surgery Manual Tibiofemoral Traction, Sham Tibiofemoral Traction - Knee Osteoarthritis (OA), Total Knee Arthroplasty (TKA) | Not applicable | Not yet recruiting | Alma Mater Europaea - Slovenia | 48 | 2026-07-22 | 2026-07-23 |
| Efficacy of Platelet-Rich Plasma Added to Hyaluronic Acid in Knee Osteoarthritis Hyaluronic Acid (HA) and Platelet rich plasma (PRP), Hyaluronic Acid (HA) - Knee Osteoarthritis, Knee Osteoarthritis (Knee OA) | Not applicable | Recruiting | Implai Sp z o.o | 50 | 2026-07-20 | 2026-08-25 |
| Efficacy of Platelet-Rich Plasma Combined With Hyaluronic Acid in Knee Osteoarthritis Hyaluronic Acid (HA) and Platelet rich plasma (PRP), Hyaluronic Acid (HA) - Knee Osteoarthritis, Knee Osteoarthritis (Knee OA) | Not applicable | Recruiting | Implai Sp z o.o | 100 | 2026-07-20 | 2026-08-25 |
| Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis Genicular Artery Embolization, Lipiodol, Simple angiogram - Knee Osteoarthritis, Knee Osteoarthritis (Knee OA) | Phase 2 | Recruiting | University of Utah | 40 | 2026-07-01 | 2026-10-30 |
| Tourniquet Vs. No-Tourniquet Technique in Total Knee Arthroplasty at the University Hospital of the West Indies pneumatic tourniquet - Knee Osteoarthritis (OA), Total Knee Anthroplasty | Not applicable | Not yet recruiting | The University of The West Indies | 30 | 2026-06-01 | 2026-04-01 |
| Altered Joint Mechanics and Biological Response in Osteoarthritic Knees. Photon counting CT scanning (PCCT scanning), Magnetic resonance imaging (MRI scanning), Gait analysis - Knee Osteoarthritis (OA) | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 30 | 2026-05-12 | 2026-07-10 |
| A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain NNC0487-0111, Placebo (matched to NNC0487-0111 ) - Obesity, Knee Osteoarthritis (OA) | Phase 3 | Recruiting | Novo Nordisk A/S | 400 | 2026-04-13 | 2026-07-09 |
| PROPRIOCEPTION, KINESIOPHOBIA AND FUNCTIONAL RECOVERY AFTER GONARTHROSIS SURGERY Knee Osteoarthritis (OA), Artrosis of the Knee | Completed | Medipol University | 47 | 2026-04-04 | 2026-09-08 | |
| Individual Differences in Gait and Osteoarthritis Pain Knee Osteoarthritis (OA), Chronic Pain | Recruiting | University of Pittsburgh | 300 | 2026-01-07 | 2026-01-29 | |
| Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR) Somatropin (recombinant human growth hormone), bacteriostatic saline placebo - Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA) | Phase 1 / Phase 2 | Active not recruiting | Dr. David Wasserstein | 34 | 2025-10-31 | 2026-07-31 |
| Electroacupuncture Versus Thread-Embedding Acupuncture for Knee Osteoarthritis Thread-Embedding Acupuncture, Electroacupuncture - Knee Osteoarthritis (OA) | Not applicable | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 60 | 2025-10-01 | 2026-06-24 |
| Functional Hip Strength Improvement in Knee Osteoarthritis Following Single-Dose PRP and a 6-Week Home Exercise Program Platelet-Rich Plasma (PRP) Injection, Home Exercise Program - Knee Osteoarthritis (OA) | Not applicable | Completed | Firat University | 27 | 2025-07-08 | 2025-12-29 |
| A Clinical Study to Evaluate the Efficacy of Native CT-II® in Individuals With Knee Osteoarthritis Native CT-II® (undenatured type II collagen), Glucosamine HCL + Chondroitin Sulphate (G+C) [Comparator], Placebo [Microcrystalline Cellulose (MCC) - Knee Osteoarthritis (OA) | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 114 | 2025-04-20 | 2026-10-01 |
| The Effect and Safety of Anti-inflammatories and Dextrose Prolotherapy Injections in Treating Knee Osteoarthritis Participants are given Ibuprofen 400 mg to take for 7 days on the day they receive a dextrose prolotherapy (DPT) injection. These procedures are repeated every 3-5 weeks for a total of 3 times., Participants are given a placebo to take for 7 days on the day they receive a dextrose prolotherapy (DPT) injection. These procedures are repeated every 3-5 weeks for a total of 3 times. - Knee Osteoarthritis (OA) | Phase 2 | Recruiting | David Grant U.S. Air Force Medical Center | 68 | 2025-03-31 | 2025-11-24 |
| Instrument-Assisted Soft Tissue Mobilization as an Adjunct to Therapeutic Exercises in Individuals With Knee Osteoarthritis IATSM, Therapeutic Exercise - Knee Osteoarthritis (OA) | Not applicable | Completed | Foundation of Medical Research and Laboratories, Pakistan | 50 | 2025-02-01 | 2026-07-17 |
| The Effect of Pulsed Radiofrequency Ablation of the Genicular Nerve on Pain, Balance, and Proprioception in Patients With Chronic Knee Osteoarthritis Genicular nerve block via radiofrequency ablation - Knee Osteoarthritis (OA), Genicular Nerves Block | Not applicable | Completed | Ankara City Hospital Bilkent | 28 | 2025-01-24 | 2026-10-13 |
| Dry Needling and Kinesio Taping as Adjuncts to Strength Training on Pain, Functional Mobility, and Quality of Life in Patients With Knee Osteoarthritis Dry Needling Combined with Strength Training, Kinesio Taping Combined with Strength Training, Strength Training - Knee Osteoarthritis (OA) | Not applicable | Completed | Foundation of Medical Research and Laboratories, Pakistan | 50 | 2024-11-01 | 2026-07-17 |
| Knee Osteoarthritis and Spa Therapy Balneotherapy program in rheumatology indication - Knee Osteoarthritis, Knee Osteoarthritis (OA) | Not applicable | Recruiting | CEN Biotech | 80 | 2024-10-14 | 2025-08-07 |
Showing 20 of 29. Sign in to see all of them.
Osteoarthritis, Knee (29) · Osteoarthritis (6) · Pain (4) · Chronic Pain (1) · Joint Diseases (1) · Musculoskeletal Diseases (1) · Musculoskeletal Pain (1) · Obesity (1) · Pain, Postoperative (1)
Arthritis (29) · Rheumatic Diseases (29) · Joint Diseases (28) · Musculoskeletal Diseases (28) · Osteoarthritis (23) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (8) · Neurologic Manifestations (7) · Pain (3) · Body Weight (1) · Muscular Diseases (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1) · Overnutrition (1) · Overweight (1)
Adrenal Cortex Hormones (1) · Aging (1) · Chondroitin (1) · Control Groups (1) · Electroacupuncture (1) · Exercise Therapy (1) · Gait Analysis (1) · Glucosamine (1) · Growth Hormone (1) · Human Growth Hormone (1) · Injections (1) · Magnetic Resonance Imaging (1) · Radiofrequency Ablation (1) · Registries (1) · Resistance Training (1)
Foundation of Medical Research and Laboratories, Pakistan (2) · Implai Sp z o.o (2) · University of Utah (2) · Alma Mater Europaea - Slovenia (1) · Ankara City Hospital Bilkent (1) · Antalya Training and Research Hospital (1) · CEN Biotech (1) · David Grant U.S. Air Force Medical Center (1) · Dr. David Wasserstein (1) · Firat University (1) · First Affiliated Hospital of Fujian Medical University (1) · GELITA (1) · LifeBridge Health (1) · MDH sp. z o.o. (1) · Medipol University (1)
United States (8) · Turkey (Türkiye) (5) · Poland (4) · Pakistan (3) · Canada (2) · China (2) · Australia (1) · Belgium (1) · Bulgaria (1) · Colombia (1) · Croatia (1) · Denmark (1) · France (1) · Greece (1) · India (1)
Malika Hassan (2) · Alexander R Kim, MD (1) · Ali Raza, MS-OMPT (1) · Benedict Alter, MD, PhD (1) · Daniel Cushman, MD (1) · Dr. David Wasserstein (1) · Harry van Lenthe, Prof. Ir. (1) · Jaromir Jarecki, DSc (1) · Maxim Christmas, DM (Orthopaedics), FACS, FCCS (1) · Osman Ahmed, MD (1) · Serhat Gulersen, MD, (1)
R01AR086796 (1), R21AR082123 (1)