16 completed, 5 active not recruiting, 5 withdrawn, 3 terminated. 35 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 35 | Completed 16, Active not recruiting 5, Withdrawn 5, Terminated 3, Not yet recruiting 2, Recruiting 2, Enrolling by invitation 1, Unknown 1 |
Follow Knee: new trials by email Literature Review of Knee trials Research Report on Knee
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autologous Adipose-Derived Stem Cell Injections for Knee Osteoarthritis Autologous Adipose-Derived Mesenchymal Stem Cells (ADMSCs), Cross-linked Hyaluronic Acid (Synovian) - Osteoarthritis, Knee | Not applicable | Recruiting | Yonsei University | 165 | 2026-09-03 | 2026-10-28 |
| ORLINT & ORLEXT: Orthosis for Knee Orlint-Orlext orthosis device, Conventional orthosis device - Knee Brace, Knee | Not applicable | Not yet recruiting | University of Salamanca | 4 | 2026-07-01 | 2026-04-28 |
| sACB vs cACB in TKA Continuous ACB, Single-shot ACB - Arthroplasty, Replacement | Not applicable | Not yet recruiting | Yonsei University | 78 | 2026-05-18 | 2026-05-12 |
| Hinge vs CCK Implants Condylar Constrained knee system. ( NexGen Legacy Condylar Constrained Knee by Zimmer Biomet), Rotating Hinge Knee ( NexGen Rotating Hinge Knee by Zimmer Biomet) - Revision Arthroplasty, Knee | Not applicable | Recruiting | Medstar Health Research Institute | 186 | 2026-02-01 | 2026-09-14 |
| The Effect of Continuous Care Counseling Based on the Roy Adaptation Model on Comfort and Quality of Life in Patients Undergoing Total Knee Arthroplasty Continuous Care Counseling Based on the Roy Adaptation Model - Osteoarthritis, Care Model | Not applicable | Completed | Cyprus International University | 60 | 2025-03-23 | 2026-10-09 |
| The Effect of Progressive Relaxation Exercises on Postoperative Pain progressive relaxation exercise - Arthroplasty, Replacement | Not applicable | Unknown | Bartın Unıversity | 96 | 2024-12-09 | 2024-07-30 |
| Effect of Knee Mobilisation on Joint Position Sense and Tissues Pulse traction, Continuous traction, Sham therapy - Manual Therapy, Knee | Not applicable | Active not recruiting | The Jerzy Kukuczka Academy of Physical Education in Katowice | 126 | 2024-09-08 | 2025-02-21 |
| WATERinMOTION Aquatic Therapy in Obese Men With Knee Osteoarthritis Aquatic Exercise, Land-Based Rehabilitation - Osteoarthritis, Knee | Not applicable | Enrolling by invitation | University of Sistan and Baluchestan | 100 | 2024-03-01 | 2025-04-27 |
| Exploration of Knee Injuries Using 3 Tesla and 7 Tesla Magnetic Resonance Imaging at the University Hospital of Poitiers 7 Tesla MRI - Traumatic Knee Injury, Knee | Not applicable | Withdrawn | Poitiers University Hospital | 2023-06-15 | 2024-03-25 | |
| Blood Flow Restriction Therapy Combined With Neuromuscular Electrostimulation in Amateur Female Soccer Players Electrostimulation, Blood flow restriction therapy - Knee | Not applicable | Completed | Universidad de Extremadura | 20 | 2023-04-15 | 2023-12-12 |
| Precision Application of Clostridium Butyricm of Clinical Research on Osteoarthritis Western Ontario and McMaster University Osteoarthritis Index (WOMAC), Visual Analogue Scale (VAS), Kellgren Lawrence Grading Scale (KL score) - Osteoarthritis, Knee | Not applicable | Completed | China Medical University Hospital | 83 | 2023-04-01 | 2024-08-26 |
| Evaluate the Performance of JOURNEY II CR and JOURNEY II BCS in TKA Populations JOURNEY II BCS Total Knee System, JOURNEY II CR Total Knee System - Arthroplasty, Replacement | Not applicable | Withdrawn | Smith & Nephew, Inc. | 2022-08-28 | 2022-06-07 | |
| Difference in Patellar Tracking Before and After Journey II BCS Total Knee Arthroplasty, Evaluated With 4D CT Imaging onlay patella button, Conventional procedure; NO onlay patella button - Knee, Replacement | Not applicable | Terminated | Sebastiaan van de Groes | 5 | 2022-04-08 | 2024-04-11 |
| To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System. CORI™ KNEE TENSIONER - Arthroplasty, Replacement | Not applicable | Completed | Smith & Nephew, Inc. | 77 | 2022-03-30 | 2026-06-30 |
| Effect of High-pressure Pulsatile Lavage Versus Manual Rinsing on Bone Cement Penetration in Total Knee Arthroplasty Bone lavage previous to cementation - Knee | Not applicable | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 100 | 2022-03-01 | 2025-11-18 |
| Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA) Procedure CORI Robotics, Conventional Procedure - Arthroplasty, Replacement | Not applicable | Active not recruiting | Smith & Nephew, Inc. | 140 | 2022-02-12 | 2026-11-03 |
| TKA Melatonin and Sleep Quality Melatonin 5 mg, Placebo (Vitamin C) - Arthroplasty, Replacement | Not applicable | Completed | Hospital for Special Surgery, New York | 176 | 2022-01-10 | 2023-09-14 |
| A Comparison of Patients Receiving a Unicompartmental Knee Replacement With Robotic Assistance or With Conventional Instrumentation NAVIO/CORI Surgical System, Non-robotic conventional instrumentation - Arthritis, Osteoarthritis | Not applicable | Withdrawn | Smith & Nephew Orthopaedics AG | 2022-01-01 | 2022-06-29 | |
| A Comparison of Patients Receiving a Total Knee Replacement With Robotic Assistance or With Conventional Instrumentation NAVIO/CORI Surgical System, Non-robotic conventional instrumentation - Arthritis, Osteoarthritis | Not applicable | Withdrawn | Smith & Nephew Orthopaedics AG | 2021-09-30 | 2022-07-11 | |
| Unicompartmental Versus Total Knee Replacement for Medial Compartment Knee Osteoarthritis Persona Partial Knee (PPK), Triathlon cruciate-retaining total knee system. - Osteoarthritis, Knee | Not applicable | Active not recruiting | Golden Jubilee National Hospital | 40 | 2021-04-26 | 2026-09-24 |
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Osteoarthritis (9) · Agnosia (2) · Arthritis (2) · Joint Diseases (2) · Musculoskeletal Diseases (2) · Osteoarthritis, Knee (2) · Pain (2) · Rheumatic Diseases (2) · Cutis Laxa (1) · Obesity (1) · Pain, Postoperative (1) · Sleep Initiation and Maintenance Disorders (1)
Arthritis (7) · Joint Diseases (7) · Musculoskeletal Diseases (7) · Rheumatic Diseases (7) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Connective Tissue Diseases (3) · Nervous System Diseases (3) · Neurologic Manifestations (3) · Skin and Connective Tissue Diseases (3) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Body Weight (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Dyssomnias (1)
Aquatic Therapy (1) · Ascorbic Acid (1) · Blood Flow Restriction Therapy (1) · Bupivacaine (1) · Hyaluronic Acid (1) · Injections, Intra-Articular (1) · Melatonin (1) · Transcutaneous Electric Nerve Stimulation (1)
Smith & Nephew, Inc. (5) · Smith & Nephew Orthopaedics AG (2) · Stryker Orthopaedics (2) · Yonsei University (2) · Bartın Unıversity (1) · China Medical University Hospital (1) · Cyprus International University (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · Fundación Santa Fe de Bogota (1) · Golden Jubilee National Hospital (1) · Goldman, Butterwick, Fitzpatrick and Groff (1) · Hospital for Special Surgery, New York (1) · Keller Army Community Hospital (1) · Materialise (1) · Medstar Health Research Institute (1)
United States (9) · United Kingdom (4) · China (3) · Ireland (3) · Spain (3) · Belgium (2) · India (2) · Netherlands (2) · Australia (1) · Brazil (1) · Canada (1) · Germany (1) · Hong Kong (1) · Iran (1) · New Zealand (1)
Iain McNamara (2) · Agnieszka Polaczek, MSc (1) · Ajay Aggarwal, MD (1) · Alejandro G Della Valle, MD (1) · Alvin Ong, MD (1) · Astrid Yung (1) · Burcu Dikmen, PhD (1) · Christine Van den Broeck, Professor (1) · Craig Della Valle, MD (1) · David Markel, MD (1) · David Wasserstein, MD (1) · Edward J Stolarski, MD (1) · Gerald E Alexander, MD (1) · Joshua Drumm, DO (1)