4 unknown, 3 completed, 3 recruiting, 2 terminated. 9 Not applicable, 2 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 3, Recruiting 3, Unknown 2, Terminated 1 |
| Phase 4 | 2 | Terminated 1, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Intractable Epilepsy: new trials by email Literature Review of Intractable Epilepsy trials Research Report on Intractable Epilepsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy stimulating probes and electrodes - Intractable Epilepsy | Not applicable | Recruiting | University of Michigan | 5 | 2025-05-05 | 2026-06-08 |
| Network Effects of Therapeutic Deep Brain Stimulation RNS/DBS activation - Intractable Epilepsy | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 25 | 2022-08-26 | 2022-10-31 |
| Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy Anticonvulsant Agent, Perampanel, Quality-of-Life Assessment - Intractable Epilepsy, Malignant Glioma | Phase 4 | Terminated | Mayo Clinic | 4 | 2020-12-04 | 2023-06-22 |
| EXPRESON-IN : Intracerebral Recordings of P3a Responses to Expressive Own-names Evoked related potentials - Intractable Epilepsy | Not applicable | Unknown | Centre Hospitalier St Anne | 20 | 2020-09-09 | 2021-07-09 |
| Pilot Trial to Evaluate The Effect of Oral Methylprednisolone on Seizure Frequency in Children With Epilepsy methylprednisolone sodium succinate, Placebo - Intractable Epilepsy, Convulsive Seizures | Phase 1 / Phase 2 | Unknown | Louisiana State University Health Sciences Center in New Orleans | 10 | 2020-02-03 | 2020-02-07 |
| Safety of Using NaviFUS System in Patients With Drug Resistant Epilepsy NaviFUS System - Drug Resistant Epilepsy, Epilepsy, Drug Resistant | Not applicable | Completed | NaviFUS Corporation | 6 | 2019-06-17 | 2020-11-13 |
| Novel Network Analysis of Intracranial Stereoelectroencephalography Combined Micro-Macro SEEG Electrodes - Epilepsy in Children, Focal Epilepsy | Not applicable | Unknown | Great Ormond Street Hospital for Children NHS Foundation Trust | 20 | 2019-06-16 | 2021-11-19 |
| Long-term Cardiac Monitoring in Epilepsy Reveal LINQ ICM System - Focal Epilepsy, Intractable Epilepsy | Not applicable | Terminated | Northwell Health | 7 | 2019-03-19 | 2023-02-08 |
| Biomarker for Creatine Deficiency Syndromes (BioCDS) Intellectual Disability, Developmental Delay | Withdrawn | CENTOGENE GmbH Rostock | 2018-08-20 | 2023-02-13 | ||
| Ketogenic Diet Drink Study Ketocal 2.5:1 - Intractable Epilepsy | Not applicable | Completed | Nutricia UK Ltd | 26 | 2017-01-04 | 2019-07-08 |
| Evaluation of Keyo in Children With Epilepsy Keyo - Intractable Epilepsy, Glucose Transporter Type 1 Deficiency Syndrome | Not applicable | Completed | Vitaflo International, Ltd | 17 | 2016-04-01 | 2024-02-16 |
| Diffusion Tensor and Functional Connectivity Imaging in Pediatric Epilepsy: Imaging/Histology Correlation Observation - Intractable Epilepsy | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 50 | 2015-11-01 | 2024-12-11 |
| The Impact of Reducing Overtreatment on Quality of Life in Children With Refractory Epilepsy Reduction of anti-epileptic medications, No drug change - Intractable Epilepsy | Phase 4 | Unknown | Institute of Child Health | 64 | 2008-09-01 | 2008-03-31 |
Drug Resistant Epilepsy (13) · Epilepsies, Partial (2) · Epilepsy (2) · Arginine-Glycine Amidinotransferase Deficiency (1) · Creatine deficiency, X-linked (1) · Epilepsy, Generalized (1) · Glioma (1) · Glut1 Deficiency Syndrome (1) · Guanidinoacetate methyltransferase deficiency (1) · Intellectual Disability (1) · Learning Disabilities (1) · Lennox Gastaut Syndrome (1) · Mental Disorders (1) · Movement Disorders (1) · Seizures (1)
Brain Diseases (13) · Central Nervous System Diseases (13) · Nervous System Diseases (13) · Epilepsy (11) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Communication Disorders (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Epileptic Syndromes (1) · Genetic Diseases, Inborn (1) · Neoplasms (1) · Neoplasms by Histologic Type (1) · Neoplasms, Germ Cell and Embryonal (1) · Neoplasms, Glandular and Epithelial (1)
Anticonvulsants (1) · Electrodes (1) · Methylprednisolone Hemisuccinate (1) · Observation (1) · perampanel (1)
The University of Texas Health Science Center, Houston (2) · CENTOGENE GmbH Rostock (1) · Centre Hospitalier St Anne (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · Institute of Child Health (1) · Louisiana State University Health Sciences Center in New Orleans (1) · Mayo Clinic (1) · NaviFUS Corporation (1) · Northwell Health (1) · Nutricia UK Ltd (1) · University of Michigan (1) · Vitaflo International, Ltd (1)
United States (6) · United Kingdom (4) · Egypt (1) · France (1) · India (1) · Sri Lanka (1) · Taiwan (1)
Helen McCullagh, BSc, MBChB (1) · Hsiang-Yu Yu, M.D. (1) · Jeremy Toler, MD (1) · Manish N Shah, M.D. (1) · Matthew Willsey, MD, PhD (1) · Peter Bauer, Prof. (1) · Rebecca Stratton, PhD (1) · Rod Scott, PhD (1) · Sandipan Pati, MD (1) · William Tatum (1)