85 completed, 20 terminated, 18 unknown, 13 recruiting. 48 Not applicable, 37 Phase 2, 12 Phase 1, 12 Phase 3, 11 Phase 4.
Follow Interstitial Cystitis: new trials by email Literature Review of Interstitial Cystitis trials Research Report on Interstitial Cystitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Venlafaxine Combined With Education and Behavioral Intervention for Bladder Pain Syndrome Venlafaxine oral tablet combined with Education and Behavioral Modification Program (EBMP), Education and Behavioral Modification Program (EBMP) only - Bladder Pain Syndrome, Chronic Pelvic Nociplastic Pain | Phase 1 | Not yet recruiting | Beijing Tiantan Hospital | 140 | 2026-12-31 | 2026-07-13 |
| Efficacy of Pulsed Electromagnetic Field and Heparin/Bupivacaine Instillations Pulsed Electromagnetic Field (PEMF) Device, Sham Pulsed Electromagnetic Feild (PEMF) Device - Interstitial Cystitis, Chronic Interstitial Cystitis | Not applicable | Withdrawn | Wake Forest University Health Sciences | 2026-05-01 | 2026-07-15 | |
| A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device, Botulinum Neurotoxin - Interstitial Cystitis, Chronic Pain | Early Phase 1 | Not yet recruiting | HillMed Inc. | 46 | 2025-09-15 | 2025-08-19 |
| Intravesical Ozone Therapy for Interstitial Cystitis/Bladder Pain Syndrome Intravesical Ozone Therapy, Placebo (Normal Saline), Control - Interstitial Cystitis, Bladder Pain Syndrome | Not applicable | Not yet recruiting | Medipol University | 60 | 2025-06-01 | 2025-04-27 |
| Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis Desert Harvest Aloe Vera Capsules, Placebo Capsules - Interstitial Cystitis, Chronic Interstitial Cystitis | Early Phase 1 | Recruiting | Wake Forest University Health Sciences | 30 | 2025-02-18 | 2026-07-28 |
| Acupuncture First for IC/BPS Acupuncture, Behavioral management, Physical therapy - Bladder Pain Syndrome, Interstitial Cystitis | Not applicable | Recruiting | University Hospitals Cleveland Medical Center | 34 | 2025-01-21 | 2026-01-08 |
| Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS) VNX001 - Interstitial Cystitis, Bladder Pain Syndrome | Phase 2 | Recruiting | Vaneltix Pharma, Inc. | 50 | 2024-12-13 | 2026-01-22 |
| Evaluating the Efficacy and Patient Experience of Catheter-Free Intravesical Instillation Catheter-Free Intravesical Instillation with a special syringe adapter - Interstitial Cystitis, Recurrent Cystitis | Recruiting | Jahn Ferenc South Pest Teaching Hospital | 300 | 2024-10-01 | 2024-12-12 | |
| Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome Clarix Flo, Placebo - Interstitial Cystitis, Painful Bladder Syndrome | Phase 2 / Phase 3 | Recruiting | David Sheyn | 100 | 2024-07-24 | 2026-09-04 |
| Auricular Acupressure Therapy for Patients With IC/BPS Auricular Acupressure - Interstitial Cystitis, Bladder Pain Syndrome | Not applicable | Withdrawn | Wake Forest University Health Sciences | 2024-07-01 | 2024-07-30 | |
| Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment Psychosocial Treatment, Pelvic Floor Physical Therapy - Chronic Interstitial Cystitis, Bladder Pain Syndrome | Not applicable | Recruiting | Vanderbilt University Medical Center | 220 | 2024-05-01 | 2026-01-21 |
| Migraine Medication Effects on Urinary Symptoms Ubrogepant, Rimegepant, Atogepant - Overactive Bladder, Bladder Pain Syndrome | Enrolling by invitation | The Cleveland Clinic | 200 | 2024-04-05 | 2026-10-19 | |
| Investigation of the Effectiveness of Acupuncture in Patients Diagnosed With Interstitial Cystitis ACUPUNCTURE - Interstitial Cystitis, Bladder Pain Syndrome | Not applicable | Completed | Medipol University | 26 | 2024-01-01 | 2026-06-30 |
| Assessing the Effectiveness and Safety of Interferon Bladder Infusion for the Treatment of Interstitial Cystitis Interferon, Sodium Hyaluronate, Sodium Chloride Injection - Interstitial Cystitis | Phase 2 / Phase 3 | Unknown | West China Hospital | 129 | 2023-10-15 | 2023-09-15 |
| Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS VNX001, Placebo, Lidocaine - Interstitial Cystitis, Bladder Pain Syndrome | Phase 2 | Recruiting | Vaneltix Pharma, Inc. | 120 | 2023-05-22 | 2026-01-22 |
| Supervised Exercise as a Therapeutic Strategy for Interstitial Cystitis/Bladder Pain Syndrome Exercise regimen - Interstitial Cystitis, Bladder Pain Syndrome | Not applicable | Withdrawn | Wake Forest University Health Sciences | 2023-05-10 | 2025-10-01 | |
| The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial) Immunonutrition - Bladder Cancer, Interstitial Cystitis | Phase 3 | Recruiting | Centre Hospitalier Universitaire Vaudois | 232 | 2023-04-10 | 2025-12-09 |
| A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome IW-3300 rectal foam, Placebo - Interstitial Cystitis, Bladder Pain Syndrome | Phase 2 | Terminated | Ironwood Pharmaceuticals, Inc. | 98 | 2023-03-28 | 2025-02-28 |
| Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO) RAS Prostatectomy, RAS Cystectomy, RAS Nephrectomy - Bladder Cancer, Prostate Cancer | Not applicable | Active not recruiting | Medtronic - MITG | 144 | 2022-12-14 | 2025-11-25 |
| A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain Multimodal Bundle Drugs, Operative Cystoscopy, Behavioral health consultation/therapy - Interstitial Cystitis, Levator Spasm | Phase 3 | Terminated | Jocelyn Fitzgerald | 26 | 2022-12-06 | 2026-04-01 |
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Cystitis, Interstitial (151) · Pelvic Pain (19) · Chronic Pain (6) · Irritable Bowel Syndrome (6) · Prostatitis (6) · Urinary Bladder Diseases (6) · Urinary Incontinence (5) · Vulvodynia (5) · Fibromyalgia (4) · Nocturia (4) · Pain (4) · Sexual Dysfunction, Physiological (4) · Urinary Bladder, Overactive (4) · Bronchiolitis Obliterans Syndrome (3) · Cystitis (3)
Female Urogenital Diseases (151) · Female Urogenital Diseases and Pregnancy Complications (151) · Male Urogenital Diseases (151) · Urogenital Diseases (150) · Urologic Diseases (150) · Cystitis (148) · Urinary Bladder Diseases (145) · Pathological Conditions, Signs and Symptoms (45) · Signs and Symptoms (38) · Neurologic Manifestations (28) · Pain (22) · Genital Diseases (18) · Genital Diseases, Male (11) · Urological Manifestations (11) · Lower Urinary Tract Symptoms (10)
Saline Solution (8) · Botulinum Toxins, Type A (6) · Heparin (5) · Sodium Chloride (5) · Administration, Intravesical (4) · Lidocaine (4) · Acupuncture Therapy (3) · Dimethyl Sulfoxide (3) · Liposomes (3) · Therapeutics (3) · 4-(4-(aminomethyl)-7a-methyl-1-methylideneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol (2) · Amitriptyline (2) · Chondroitin Sulfates (2) · Cystoscopy (2) · Gabapentin (2)
Wake Forest University Health Sciences (7) · Corewell Health East (6) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (6) · Kenneth Peters, MD (5) · St. Louis University (5) · Asan Medical Center (4) · Buddhist Tzu Chi General Hospital (4) · University of New Mexico (4) · University of Pennsylvania (4) · Allergan (3) · Assaf-Harofeh Medical Center (3) · Samsung Medical Center (3) · Urigen (3) · Aquinox Pharmaceuticals (Canada) Inc. (2) · Boston Children's Hospital (2)
United States (96) · Canada (14) · South Korea (8) · Taiwan (7) · Denmark (4) · Hungary (4) · Israel (4) · Belgium (3) · Czechia (3) · Egypt (3) · Germany (3) · Poland (3) · Turkey (Türkiye) (3) · United Kingdom (3) · Latvia (2)
Curtis Nickel, MD (4) · Kenneth M Peters, MD (4) · Kenneth Peters, MD (4) · Hann-Chorng Kuo, M.D. (3) · Stephen J Walker, PhD (3) · Stephen Walker, PhD (3) · C. Lowell Parsons, MD (2) · Claire Yang, MD (2) · David Burks, MD (2) · David Sheyn, MD (2) · Eugen C Campian, MD (2) · Harris Foster, MD (2) · Ioana Marcu, MD (2) · John Kusek, PhD (2) · Kobi Stav, MD (2)
PMID 32734597, PMID 11489726, PMID 15183555, PMID 19400928, PMID 19535099, PMID 20303115, PMID 21375763, PMID 22503015, PMID 22818144, PMID 23234638, PMID 23670165, PMID 23792149, PMID 25085007, PMID 25085119, PMID 25209396, PMID 25596361, PMID 26384156, PMID 27378135, PMID 30212850, PMID 30452963, PMID 31050659, PMID 31690286, PMID 32394478, PMID 32939046, PMID 33535797, PMID 33831942, PMID 35704106, PMID 35964133, PMID 36269028, PMID 36279178, PMID 36910591, PMID 37278657, PMID 38587846, PMID 38768800, PMID 39261949, PMID 39415282, PMID 39432808, PMID 39704257, PMID 39746210, PMID 39787060, PMID 40387787, PMID 40415481, PMID 41564284, PMID 42132526, PMID 42604487, PMID 42857927
U01DK065209 (3), U01DK082316 (3), 2009 (1), 2016 (1), K23DK118118 (1), R01DK049524 (1), R01DK051413 (1), R01DK103769 (1), R01DK128233 (1), R01DK133415 (1), R01ES015382 (1), R01HD096331 (1)