86 completed, 16 recruiting, 10 unknown, 7 terminated. 43 Not applicable, 25 Phase 3, 19 Phase 2, 19 Phase 4, 12 Phase 1.
Follow Nocturia: new trials by email Literature Review of Nocturia trials Research Report on Nocturia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| How Well and Safely Does Lemborexant Work for People Who Wake up at Night to Urinate (LENS) Lemborexant tablets, Placebo - Nocturia | Phase 4 | Not yet recruiting | University of Alberta | 35 | 2026-10-15 | 2026-09-25 |
| Addressing Nocturia in Older Women Utilizing Behavioral Sleep Intervention and Brief Mindfulness Brief behavioral treatment of insomnia, MI, Control - Nocturia, Insomnia | Not applicable | Not yet recruiting | University of Pittsburgh | 80 | 2026-09-15 | 2026-08-12 |
| Electroacupuncture as a Treatment for Refractory Overactive Bladder Name: Electroacupuncture (EA) Type: Device-based acupuncture therapy, Neuromodulation therapy - Over Active Bladder, Urinary Incontinence (UI) | Not applicable | Recruiting | Chelsea and Westminster NHS Foundation Trust | 24 | 2026-08-15 | 2026-08-28 |
| Low-Intensity Shock Wave Therapy for Refractory Overactive Bladder in Women Low-Intensity Extracorporeal Shock Wave Therapy, Sham Low-Intensity Extracorporeal Shock Wave Therapy - Urinary Bladder, Overactive | Not applicable | Not yet recruiting | Al-Azhar University | 40 | 2026-08-01 | 2026-07-31 |
| A Novel Wearable Transcutaneous Tibial Nerve Stimulation (TTNS) Device in the Treatment of Patients With Overactive Bladder (OAB) and Nocturia A new wearable transcutaneous tibial nerve stimulation (TTNS) device, behavioral therapy - Overactive Bladder (OAB), Nocturia | Not applicable | Not yet recruiting | Qilu Hospital of Shandong University | 80 | 2026-06-10 | 2026-06-09 |
| A Community-based Solution for Nocturia: Integrating Digital Technology and Behavioral Interventions Home Uroflowmetry, Voiding Diary - Nocturia, Sleep Disturbanc | Not applicable | Recruiting | National Taiwan University Hospital | 50 | 2026-04-08 | 2026-07-29 |
| Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer. Urolift - Benign Prostatic Hyperplasia | Not applicable | Recruiting | Northwell Health | 20 | 2026-02-11 | 2026-09-29 |
| An Evaluation of the PureWick™ Male External Catheter Versus an Established Comparator Overnight in the Home Setting for Incontinence in Adult Males PureWick System, UltraFlex Self-Adhering Male External Catheter - Urinary Incontinence | Not applicable | Completed | C. R. Bard | 120 | 2025-11-21 | 2026-08-04 |
| The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled Trial Mirabegron 25mg, Solifenacin 5 mg, Tolterodine 4 mg - Urinary Bladder, Overactive | Phase 3 | Not yet recruiting | Far Eastern Memorial Hospital | 220 | 2025-08-07 | 2025-08-11 |
| Solifenacin Plus Tadalafil vs Solifenacin Alone for Overactive Bladder in Females Solifenacin, Tadalafil - Overactive Bladder | Not applicable | Completed | Ain Shams University | 80 | 2025-05-15 | 2025-12-31 |
| This Study Will Collect Clinical and Patient Reported Satisfaction Data From Males Requiring Urine Output Management Overnight in the Home Setting. PureWick® Urine Collection System, UltraFlex™ Self-Adhering Male External Catheter - Urinary Incontinence | Not applicable | Completed | C. R. Bard | 15 | 2025-03-21 | 2026-10-21 |
| Safety and Performance of UCon Patch Electrode Time Limited stimulation, Sham stimulation - Urinary Incontinence, Urinary Incontinence, Urge | Not applicable | Recruiting | InnoCon Medical | 180 | 2025-03-20 | 2025-03-27 |
| APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women RiSolve App, AUGS Patient Handouts - Overactive Bladder (OAB), Urinary Urgency | Not applicable | Recruiting | Medstar Health Research Institute | 596 | 2025-03-17 | 2025-10-27 |
| Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis Desert Harvest Aloe Vera Capsules, Placebo Capsules - Interstitial Cystitis, Chronic Interstitial Cystitis | Early Phase 1 | Recruiting | Wake Forest University Health Sciences | 30 | 2025-02-18 | 2026-07-28 |
| Low-Energy Shock Wave Therapy for Overactive Bladder in Women With Metabolic Syndrome Low-Energy Extracorporeal Shock Wave Therapy (LiESWT), Sham Shock Wave Therapy - Bladder, Lower Urinary Track Symptoms | Not applicable | Recruiting | KMUHIRB-F(I)-20230051 | 60 | 2025-02-10 | 2026-05-04 |
| Moxibustion for Nocturia Moxibustion - Nocturia, Acupoint | Not applicable | Recruiting | Buddhist Tzu Chi General Hospital | 100 | 2025-01-01 | 2026-05-20 |
| Examination of the Effect of Nocturia on Pelvic Floor Symptoms, Sleep Parameters and Quality of Life in Women With Urinary Incontinence Women, Urinary Incontinence (UI) | Completed | Gulhane School of Medicine | 102 | 2025-01-01 | 2026-09-23 | |
| Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Syndrome and Associated Gait Changes in Post-menopausal Women Transcutaneous tibial nerve stimulation - Overactive Bladder Syndrome, Urinary Incontinence, Urge | Not applicable | Unknown | Louisiana State University Health Sciences Center Shreveport | 60 | 2024-10-01 | 2024-09-27 |
| Pathophysiologic Study to Understand and Possibly Treat Nocturia Compression stockings - Nocturia | Not applicable | Withdrawn | NYU Langone Health | 2024-08-01 | 2024-09-26 | |
| Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Women vaginal 17 beta-estradiol, Placebo, Behavioral modifications - Lower Urinary Tract Symptoms, Female Genitourinary Disease | Phase 4 | Completed | Mahidol University | 86 | 2024-04-08 | 2025-04-20 |
Showing 20 of 131. Sign in to see all of them.
Urinary Bladder, Overactive (24) · Urinary Incontinence (22) · Urinary Incontinence, Urge (16) · Lower Urinary Tract Symptoms (10) · Nocturnal Enuresis (8) · Prostatic Hyperplasia (8) · Sleep Apnea, Obstructive (5) · Sleep Initiation and Maintenance Disorders (5) · Cystitis, Interstitial (4) · Parkinson Disease (4) · Fecal Incontinence (3) · Polyuria (3) · Anxiety Disorders (2) · Hyponatremia (2)
Pathological Conditions, Signs and Symptoms (131) · Signs and Symptoms (131) · Urological Manifestations (131) · Lower Urinary Tract Symptoms (121) · Male Urogenital Diseases (59) · Urogenital Diseases (59) · Female Urogenital Diseases and Pregnancy Complications (49) · Female Urogenital Diseases (48) · Urologic Diseases (48) · Urination Disorders (34) · Urinary Bladder Diseases (28) · Mental Disorders (21) · Nervous System Diseases (20) · Sleep Wake Disorders (13) · Dyssomnias (11)
Deamino Arginine Vasopressin (17) · Solifenacin Succinate (7) · mirabegron (7) · Surveys and Questionnaires (4) · Blood Specimen Collection (3) · Acupuncture Therapy (2) · Behavior Therapy (2) · Sugars (2) · Tolterodine Tartrate (2) · silodosin (2) · Behavior Control (1) · Botulinum Toxins, Type A (1) · Cellulose (1) · Chronotherapy (1) · Clinical Laboratory Techniques (1)
Ferring Pharmaceuticals (18) · Vantia Ltd (10) · University Hospital, Ghent (9) · Serenity Pharmaceuticals, Inc. (6) · InnoCon Medical (4) · Atlanta VA Medical Center (3) · National Taiwan University Hospital (3) · Seoul National University Hospital (3) · University of Pittsburgh (3) · Astellas Pharma Europe B.V. (2) · Astellas Pharma Inc (2) · Barrie Urology Associates (2) · C. R. Bard (2) · Loyola University (2) · Northwell Health (2)
United States (56) · Belgium (13) · Canada (12) · Germany (9) · South Korea (8) · United Kingdom (8) · Czechia (7) · Denmark (7) · Japan (6) · Spain (6) · Taiwan (6) · China (3) · Egypt (3) · Hungary (3) · Netherlands (3)
Karel Everaert, MD, PhD (3) · Bilal Chughtai, MD (2) · E. Camille Vaughan, MD, MS (2) · Joseph A Zadra, MD CM FRCSC (2) · Peter Christensen, MD (2) · Ralph Schutz (2) · Shachi Tyagi, MD, MS (2) · Stephen Walker, PhD (2) · Adrian Wagg (1) · Aftab Ahmed Mirza Baig, DPT, MSAPT (1) · Alan Wolfe, PhD (1) · Alison Huang, MD (1)
PMID 21367921, PMID 27862898, PMID 31397969, PMID 10699609, PMID 19100605, PMID 19302497, PMID 19941278, PMID 20567947, PMID 20590544, PMID 21092997, PMID 21420124, PMID 22447415, PMID 22581511, PMID 23370938, PMID 23454402, PMID 23454404, PMID 24176946, PMID 25022469, PMID 25172115, PMID 25236993, PMID 25238744, PMID 25937539, PMID 26068624, PMID 26314640, PMID 27321890, PMID 28029383, PMID 28150436, PMID 28731583, PMID 29385990, PMID 29398096, PMID 29866467, PMID 30592553, PMID 31956723, PMID 32791124, PMID 33117961, PMID 35543540, PMID 35550708, PMID 35622269, PMID 35908067, PMID 37160401, PMID 37481065, PMID 40135809, PMID 40658410, PMID 41041560, PMID 41281576, PMID 41368330, PMID 41420462, PMID 41692807, PMID 42257317, PMID 42836930
2016 (1), 2017 (1), K24AG068601 (1), R01AG076575 (1), R21AG060292 (1), R21AG095656 (1), R33AG057806 (1)