24 completed, 7 recruiting, 3 terminated, 3 unknown. 15 Phase 2, 13 Phase 1, 9 Not applicable, 7 Phase 3, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial) Azacitidine, Bone Marrow Aspiration and Biopsy, Cytarabine - Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 2 | Not yet recruiting | National Cancer Institute (NCI) | 184 | 2027-01-04 | 2026-10-01 |
| Human Absorption Study of Liposomal Glucosamine Supplements High-Emulsified Liposomal Glucosamine Liquid, Low-Emulsified Liposomal Glucosamine Liquid, Glucosamine Liquid without Liposomal - Glucosamine, Liposomal Encapsulation | Not applicable | Recruiting | TCI Co., Ltd. | 16 | 2026-10-21 | 2026-09-28 |
| Safety and Efficacy of Liposomal Amphotericin B for Patients With Invasive Mold Diseases in Liver Transplant Recipients AmBisome (Amphotericin B) Liposome - Invasive Mold Diseases | Not applicable | Not yet recruiting | Beijing Friendship Hospital | 60 | 2026-08-08 | 2026-07-24 |
| Effect of Double Nutri® Liposomal Encapsulation Technology on Human Absorption of Vitamin C and Glutathione Liquid Sachet Vitamin C and Glutathione without liposome, Liposomal Vitamin C and Glutathione - Vitamin C, Glutathione | Not applicable | Completed | TCI Co., Ltd. | 20 | 2025-12-15 | 2026-02-03 |
| Efficacy and Safety of Topical Amphotericin B Solution in Treatment of Resistant Tinea Capitis in Children 16 Years Old or Less we Follow up Cases Weekly up to 8 Weeks and Notice Improvement of Itching ,Scaling, and Hair Regrowth Then Fungal Culture Done to See if the Solution Working Amphotericine in liposome (Ambisome®) - Tinea Capitis | Phase 2 / Phase 3 | Active not recruiting | Sohag University | 30 | 2025-04-01 | 2025-05-20 |
| Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial) Azacitidine, Biospecimen Collection, Bone Marrow Aspiration - Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | Phase 2 | Recruiting | National Cancer Institute (NCI) | 335 | 2024-09-25 | 2026-10-21 |
| A Clinical Study to Assess Safety, Efficacy and In-use Tolerability of Different Dosages of Hair Growth Products in Patients With Mild to Moderate Androgenic Alopecia (Grade I to III). SesZen-Bio Low Dose 1 (350 mg extract), SesZen-Bio Low Dose 1 (150 mg liposomal), SesZen-Bio High Dose 1 (500 mg extract) - Androgenic Alopecia | Not applicable | Completed | NovoBliss Research Pvt Ltd | 72 | 2024-09-23 | 2026-07-31 |
| MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial) Allogeneic Hematopoietic Stem Cell Transplantation, Azacitidine, Best Practice - Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | Phase 2 | Recruiting | National Cancer Institute (NCI) | 2000 | 2024-06-18 | 2026-10-23 |
| Tazemetostat and Palbociclib With CPX-351for R/R AML Tazemetostat, Liposome-encapsulated Daunorubicin-Cytarabine, Bone Marrow Aspiration and Biopsy - Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia | Phase 1 | Recruiting | Thomas Jefferson University | 24 | 2023-08-28 | 2026-03-12 |
| A Bioequivalence Study of (Cytarabine: Daunorubicin) Liposome for Injection (cytarabine: daunorubicin) liposome for injection, Vyxeos - Acute Myeloid Leukemia | Not applicable | Unknown | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 36 | 2023-08-25 | 2023-09-21 |
| A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat Anti-CD123 ADC IMGN632, Bone Marrow Aspiration and Biopsy, Cytarabine - Recurrent Acute Myeloid Leukemia, Recurrent B Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Withdrawn | Children's Oncology Group | 2023-08-01 | 2023-09-01 | |
| Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes Biospecimen Collection, Bone Marrow Aspiration and Biopsy, Liposome-encapsulated Daunorubicin-Cytarabine - Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 49 | 2022-08-24 | 2026-06-30 |
| ex Vivo Study of Liposomes Loaded With Everolimus in Chronic Lung Allograft Disfunction Liposomes - Bronchiolitis Obliterans Syndrome (BOS) | Completed | Fondazione IRCCS Policlinico San Matteo di Pavia | 19 | 2022-03-19 | 2025-11-18 | |
| Efficacy of "Aquoral Lipo" Artificial Tears in Contact Lens Wearers With Discomfort Aquoral Lipo (Esteve), Hyabak (Thea) - Contact Lens Complication | Not applicable | Completed | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 41 | 2022-03-01 | 2024-10-08 |
| CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease Allogeneic Hematopoietic Stem Cell Transplantation, Liposome-encapsulated Daunorubicin-Cytarabine - Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts-2 | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 1 | 2021-08-09 | 2024-05-23 |
| Liposomal Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin for the Treatment of Relapsed Refractory Pediatric Patients With Acute Myeloid Leukemia Gemtuzumab Ozogamicin, Liposome-encapsulated Daunorubicin-Cytarabine - Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia | Phase 1 | Completed | M.D. Anderson Cancer Center | 1 | 2021-05-21 | 2026-05-20 |
| Vyxeos® With Clofarabine for Pediatric AML Vyxeos 44 MG / 100 MG Liposome Injection, Clofarabine - Relapsed Pediatric AML, Refractory Pediatric AML | Phase 1 | Recruiting | Princess Maxima Center for Pediatric Oncology | 25 | 2020-11-06 | 2025-09-05 |
| A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations Allogeneic Hematopoietic Stem Cell Transplantation, Asparaginase Erwinia chrysanthemi, Biospecimen Collection - Acute Myeloid Leukemia | Phase 3 | Recruiting | Children's Oncology Group | 1400 | 2020-07-21 | 2026-09-17 |
| CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients Liposome-encapsulated Daunorubicin-Cytarabine, Cladribine, Cytarabine - Acute Myeloid Leukemia, Myeloid Neoplasm | Phase 2 | Completed | Fred Hutchinson Cancer Center | 60 | 2020-05-27 | 2026-06-29 |
| The Effect of Liposome Vitamin C on the Absorption and Metabolism of the Human Body. vitamin C without liposome, liposomal process A vitamin C, liposomal process B vitamin C (Double Nutri™) - Vitamin C Deficiency | Not applicable | Completed | TCI Co., Ltd. | 11 | 2019-06-10 | 2021-05-14 |
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Leukemia, Myeloid, Acute (12) · Acquired Immunodeficiency Syndrome (5) · HIV Infections (5) · Sarcoma, Kaposi (5) · Myeloproliferative Disorders (4) · Cystitis, Interstitial (3) · Leukemia, Monocytic, Acute (2) · Myelodysplastic Syndromes (2) · Neoplasm Metastasis (2) · Alopecia (1) · Ascorbic Acid Deficiency (1) · Breast Neoplasms (1) · Bronchiolitis Obliterans Syndrome (1) · Burkitt Lymphoma (1) · Colonic Neoplasms (1)
M.D. Anderson Cancer Center (5) · National Cancer Institute (NCI) (4) · Sequus Pharmaceuticals (4) · Children's Oncology Group (3) · TCI Co., Ltd. (3) · Fred Hutchinson Cancer Center (2) · Jazz Pharmaceuticals (2) · Kenneth Peters, MD (2) · Aurobindo Pharma Ltd (1) · Beijing Friendship Hospital (1) · British University In Egypt (1) · Buddhist Tzu Chi General Hospital (1) · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. (1) · Fondazione IRCCS Policlinico San Matteo di Pavia (1) · Fovea (1)
United States (23) · Canada (5) · Taiwan (5) · Puerto Rico (3) · Spain (3) · India (2) · Italy (2) · Australia (1) · Austria (1) · Bangladesh (1) · Brazil (1) · China (1) · Denmark (1) · Egypt (1) · France (1)
Kenneth M Peters, MD (2) · Todd M Cooper (2) · Tong-Lin Wu (2) · Apostolia Tsimberidou, MD, PhD (1) · Arthur Louie, M.D. (1) · Arthur Louie, MD (1) · Boleslav Kosharskyy, MD (1) · Branko Cuglievan (1) · C.M. Zwaan, Prof. dr. (1) · Daniel Karp, MD (1) · Dr. Dinesh Mondal, MD (1) · Dr. Krishna Pandey, MD (1) · Dr. Nayan K Patel (1) · Dr. Sajid Mohd, MD (1) · Dr. Shyam Sundar, MD (1)
PMID 21831487, PMID 22840315, PMID 25209396, PMID 28531175, PMID 32401633, PMID 32734597, PMID 33843815, PMID 36902217, PMID 38107263, PMID 38947228, PMID 40401707, PMID 40847743, PMID 42497367
U10CA180886 (3), U10CA180888 (2), 2016 (1), 2023 (1), R01CA152228 (1), U10CA180820 (1), UM1CA186712 (1)