6 not yet recruiting, 5 recruiting, 3 completed, 2 active not recruiting. 10 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Not yet recruiting 4, Recruiting 3, Completed 2, Active not recruiting 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Intensive Care Units (ICUs): new trials by email Literature Review of Intensive Care Units (ICUs) trials Research Report on Intensive Care Units (ICUs)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial Esketamine combined with dexmedetomidine, Dexmedetomidine - Dexmedetomidine, Ketamine | Phase 4 | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 356 | 2026-09-28 | 2026-09-03 |
| The Effect of Changes in the Frequency of Endotracheal Tube Repositioning in Intensive Care Units on the Prevention of Oral Mucosal Pressure Injuries Changes in the frequency of endotracheal tube repositioning - Mucosal Wound, Mucosal Erosion | Not applicable | Not yet recruiting | Hacettepe University | 230 | 2026-06-30 | 2026-06-25 |
| Body Lateralization and Its Effects on Respiratory Drive, Ventilation, and Pulmonary Aeration in Critically Ill Patients Automatic Lateralization Therapy, Supine Positioning - Intensive Care Units (ICUs) | Not applicable | Recruiting | University of Pernambuco | 30 | 2026-01-01 | 2026-01-09 |
| Prevention of Phlebitis, Infiltration and Extravasation With Infusion Monitoring System Infusion monitoring system developed for use by nurses in patient care - Extravasation, Intensive Care Units (ICUs) | Not applicable | Not yet recruiting | Ordu University | 102 | 2025-11-08 | 2025-11-17 |
| Assessment of the PEEP Responsiveness to Titrate End-expiratory Pressure and of the Need for Muscle Relaxation During Prone Positioning in Moderate-to-severe Acute Respiratory Distress Syndrome: A Master Protocol Minimal distension, Maximal Recruitment, Prone position + early NMBAs - Acute Respiratory Distress Syndrome (ARDS), Intensive Care Units (ICUs) | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 1200 | 2025-11-05 | 2026-08-28 |
| Effects of Artificial Intelligence Nurse Orientation Program on Psychological Outcomes and Length of Hospital Stay in Intensive Care Unit Structured orientation program, Human Nurse - Delirium, Anxiety and Depression | Not applicable | Not yet recruiting | Koç University | 10 | 2025-11-01 | 2025-09-15 |
| Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive Care Unit. Mechanical Ventilation, Pulmonary Rehabilitation | Recruiting | Universita degli Studi di Genova | 2400 | 2025-10-01 | 2026-09-15 | |
| Neuromuscular Electrical Stimulation in Critically Ill Patients Aged 80 and Over Medium Frequency Neuromuscular Electrical Stimulation (NMES), Standard physical therapy - Intensive Care Units (ICUs), Muscle Atrophy or Weakness | Not applicable | Not yet recruiting | Universidad de La Frontera | 30 | 2025-09-01 | 2025-08-17 |
| Evaluation of Pressure Injury Risks in Hemofiltration Identifying the risks of pressure injuries - Pressure Ulcer (PU), Hemofiltration | Not applicable | Completed | Ogr. Uyesi Naile | 109 | 2025-07-15 | 2026-09-17 |
| Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit Critical Illness, Intensive Care Units (ICUs) | Recruiting | Leiden University Medical Center | 60 | 2025-07-08 | 2025-11-26 | |
| Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials No Pressure Support No Positive End Expiratory Pressure Spontaneous Breathing Trial, Pressure Support Spontaneous Breathing trial, Humidified High Flow Spontaneous Breathing Trial - Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema | Not applicable | Recruiting | Centre Hospitalier Régional d'Orléans | 24 | 2025-04-30 | 2026-05-22 |
| Adaptation of the Intensive Care Unit-specific Pressure Injury Risk Scale to Turkish (RAPS-ICU) Pressure Injury, Reliability and Validity | Not yet recruiting | Harran University | 60 | 2025-03-30 | 2025-04-03 | |
| Continuous Connected Patient Care (CCPC), a Pilot Testing a Novel Device for Continuous Vitals Monitoring - Department of Anesthesia at PHC Surgical Procedure, Unspecified, Intensive Care Units (ICUs) | Active not recruiting | Medtronic - MITG | 50 | 2025-03-13 | 2026-10-15 | |
| Study Protocol for a Pilot Randomized Controlled Trial of a Psychosocial Care Intervention in Intensive Care integrated psychosocial care - Psychosocial Intervention, Intensive Care Units (ICUs) | Not applicable | Active not recruiting | Harald Gündel | 375 | 2024-08-01 | 2025-07-01 |
| Application Effect Analysis of Bundle Nursing Intervention routine ICU nursing, HAI prevention, prevention and control collaboration - Patient Care Bundles, Interdisciplinary Communication | Not applicable | Completed | The First Hospital of Qinhuangdao | 120 | 2023-01-01 | 2026-06-18 |
| FRench-speAking Icu (Intensive Care Unit) Nutritional Survey no intervention - Intensive Care Units (ICUs) | Completed | Assistance Publique - Hôpitaux de Paris | 1215 | 2015-03-01 | 2023-02-03 |
Critical Illness (2) · Pressure Ulcer (2) · Agnosia (1) · Anxiety Disorders (1) · Asthenia (1) · Cross Infection (1) · Delirium (1) · Depression (1) · Muscular Atrophy (1) · Orientation, Spatial (1) · Phlebitis (1) · Psychomotor Agitation (1) · Respiratory Distress Syndrome (1)
Pathological Conditions, Signs and Symptoms (6) · Disease Attributes (3) · Nervous System Diseases (3) · Neurologic Manifestations (3) · Pathologic Processes (3) · Signs and Symptoms (3) · Behavior (2) · Behavioral Symptoms (2) · Neurobehavioral Manifestations (2) · Skin Diseases (2) · Skin Ulcer (2) · Skin and Connective Tissue Diseases (2) · Aberrant Motor Behavior in Dementia (1) · Atrophy (1) · Cardiovascular Diseases (1)
Dexmedetomidine (1) · Efficiency (1) · Fumigant 93 (1) · Patient Care (1) · Prone Position (1) · Supine Position (1)
Assistance Publique - Hôpitaux de Paris (2) · Centre Hospitalier Régional d'Orléans (1) · Hacettepe University (1) · Harald Gündel (1) · Harran University (1) · Koç University (1) · Leiden University Medical Center (1) · Medtronic - MITG (1) · Ogr. Uyesi Naile (1) · Ordu University (1) · The First Affiliated Hospital with Nanjing Medical University (1) · The First Hospital of Qinhuangdao (1) · Universidad de La Frontera (1) · Universita degli Studi di Genova (1) · University of Pernambuco (1)
Turkey (Türkiye) (3) · China (2) · France (2) · Brazil (1) · Canada (1) · Chile (1) · Germany (1) · Italy (1) · Netherlands (1)
Ary Serpa Neto, MD, PhD (1) · Carol L. Hodgson, PhD FACP FAHMS BAppSc(PT) MPhi (1) · Denise Battaglini, MD, PhD (1) · Fatma Aksoy, MscN (1) · Gabriel Nasri Marzuca-Nassr, PhD (1) · Gentle S. Shrestha, MD, PhD (1) · Irene Schiavetti, PhD (1) · Marcus J Schultz, MD, PhD (1) · Ricardo Kenji Nawa, MD, PhD (1) · Rik Gosselink, PT, PhD (1) · Sabrine N.T. Hemmes, MD, PhD (1)
PMID 18283429, PMID 18511703, PMID 19446324, PMID 24247473, PMID 27864615, PMID 28979394, PMID 31970446, PMID 32666602, PMID 36286256, PMID 36611211, PMID 37428547, PMID 38101991, PMID 39787945, PMID 40068960, PMID 42224383, PMID 42265981