77 completed, 5 unknown, 4 recruiting, 3 terminated. 50 Phase 1, 15 Not applicable, 6 Phase 3, 4 Phase 4, 2 Early Phase 1.
Follow Hypolipoproteinemias: new trials by email Literature Review of Hypolipoproteinemias trials Research Report on Hypolipoproteinemias
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single and Multiple Dose Study to Evaluate Safety and Pharmacokinetics of BMS-986533 in Healthy Participants and Assessments of Food and pH Effects on Relative Bioavailability, and Drug-Drug Interaction Potential in Healthy Participants BMS-986533, Famotidine, Placebo - Healthy Volunteers | Phase 1 | Recruiting | Bristol-Myers Squibb | 136 | 2026-07-13 | 2026-07-24 |
| The Food Effect on Pharmacokinetics of Fixed Dose Combination of Gemigliptin/Dapagliflozin/Metformin in Healthy Volunteers Fixed-dose combination of gemigliptin/dapagliflozin/metformin 50/10/1000 mg - Healthy, Fasting | Phase 1 | Completed | LG Chem | 28 | 2026-06-11 | 2026-09-10 |
| A Study to Investigate the Effect of Food on Balcinrenone/Dapagliflozin Pharmacokinetics in Fed and Fasted State and Pharmacokinetics of Balcinrenone When Dosed With a P-gp Inhibitor in Healthy Participants. balcinrenone/ dapagliflozin, quinidine - Healthy Participants | Phase 1 | Completed | AstraZeneca | 14 | 2025-05-20 | 2025-08-12 |
| Exploring Physical Exercise for the Regulation and Control of Metabolic Disorders in College Students. Physical exercise prescription: Continuous aerobic training (jogging, swimming, static cycling), Control group: Continuous aerobic physical exercise - Metabolic Disorders, Abdominal Obesity | Not applicable | Unknown | Universidad de Colima | 48 | 2024-09-01 | 2024-08-15 |
| Atlantic Lipid Lowering Treatment Optimization Program Supportive care - Familial Hypercholesterolemia, Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia | Not applicable | Recruiting | Atlantic Health System | 250 | 2024-07-01 | 2025-08-03 |
| Pharmacokinetics of AUX-001 40mg Once-daily in Healthy Subjects Under Fasting and Fed Conditions AUX-001 40mg once-daily - Chronic Stable Angina | Early Phase 1 | Unknown | Auxilius Pharma sp.z.o.o. | 16 | 2023-11-27 | 2024-02-12 |
| A Study to Compare the Relative Bioavailability of Two Iberdomide (CC-220) Formulations and to Assess The Effect Of Food on the Drug Levels of Iberdomide in Healthy Adult Participants Iberdomide - Healthy Volunteers | Phase 1 | Completed | Bristol-Myers Squibb | 32 | 2023-05-18 | 2024-07-26 |
| Development of the Leeds Food Preference Questionnaire in Spanish Standardized meal - Fasting, Fed | Not applicable | Unknown | Universidad de Granada | 50 | 2023-03-07 | 2023-05-01 |
| The Effect of Tele-Nursing Based Motivational Interviewing in Individuals With Type 2 Diabetes:RCT Tele-Nursing based Motivational Interviewing - Type2 Diabetes, Self Efficacy | Not applicable | Completed | Pamukkale University | 70 | 2023-02-01 | 2024-03-13 |
| Comparative Bioavailability Study of TAH3311 5 mg Oral Dissolving Film vs ELIQUIS® 5 mg Tablet in Healthy Volunteers Apixaban 5 mg Oral Dissolving Film (TAH3311) and Tablet (Eliquis®) - Healthy Volunteers, Fasting | Early Phase 1 | Completed | TAHO Pharmaceuticals Ltd. | 12 | 2022-12-05 | 2023-08-18 |
| In Vivo Metabolism of apoB-containing Lipoproteins in ANGPTL3 Deficient Subjects Administration of deuterated compounds for kinetic study - Familial Hypobetalipoproteinemia, Familial Hypobetalipoproteinemia - Heterozygous Form | Not applicable | Unknown | Marcello Arca | 20 | 2022-09-30 | 2022-10-10 |
| LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study Demographics, diagnosis type, genotype, lipid profile, renal function profile, treatment allocation, ophthalmology exam, country of residence. - LCAT Deficiency | Recruiting | University of Pennsylvania | 40 | 2022-08-12 | 2026-05-06 | |
| CArotenoid in hypoChOlesterolemia Characterization of carotenoid status and plasma levels of oxidative stress markers in patients (case group only), Characterization, evaluation and comparison of macular pigment density - Primary Intestinal Hypocholesterolemia, Abetalipoproteinemia | Completed | Hospices Civils de Lyon | 10 | 2022-06-30 | 2025-12-04 | |
| Bioequivalence Study of Rivaroxaban 2.5 mg Tablets Under Fasting and Fed Conditions Rivaroxaban 2.5 mg Test Tablet, Rivaroxaban 2.5 mg Reference Tablet - Healthy Participants | Phase 1 | Completed | The Affiliated Hospital of Qingdao University | 64 | 2022-03-16 | 2026-09-08 |
| Decrease in Paraoxonase Enzyme Level and Myocardial İnfarction paraoxanase enzyme level - Myocardial Infarction, High-Density Lipoid Deficiency | Completed | Bezmialem Vakif University | 200 | 2019-12-30 | 2022-05-31 | |
| Adiponectin, ICAM-1, VCAM-1 Levels and Metabolic Syndrome in Obese Adolescents Nur Aisiyah Widjaja - Obesity, Abdominal Obesity | Completed | Universitas Airlangga | 125 | 2019-10-01 | 2023-01-13 | |
| Intermittent Fasting in Dyslipidemia Fasting (diet restruction for specific period) - Intermittent Fasting, Dyslipidemias | Not applicable | Unknown | Aga Khan University | 60 | 2019-02-20 | 2019-02-21 |
| The Prognosis of Lipid Reprogramming With Rosuvastatin, in Castrated Egyptian Prostate Cancer Patients Rosuvastatin 20mg, surgical castration - Prostate Cancer Metastatic | Phase 4 | Completed | National Cancer Institute, Egypt | 70 | 2019-01-15 | 2021-03-02 |
| Prevalence of fAmilial hypobetalipopRoTeinemIa in psychiaTrIc pOpulatioN (PARTITION) Psychiatric population - Familial Hypobetalipoproteinemia | Not applicable | Completed | Nantes University Hospital | 896 | 2018-08-22 | 2021-09-16 |
| Habitual Diet and Avocado Trial Intervention Daily Avocado - Intra-abdominal Fat, Metabolic Syndrome | Not applicable | Completed | Wake Forest University Health Sciences | 1008 | 2018-06-19 | 2023-03-22 |
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Lecithin Cholesterol Acyltransferase Deficiency (62) · Fasting (17) · Hypoalphalipoproteinemias (14) · Hypobetalipoproteinemias (7) · Cardiovascular Diseases (5) · Tangier Disease (5) · Abetalipoproteinemia (4) · Dyslipidemias (4) · Hypercholesterolemia (3) · Hyperglycemia (3) · Hypertension (3) · Hypertriglyceridemia (3) · Metabolic Syndrome (3) · Retinitis Pigmentosa (3)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (91) · Nutritional and Metabolic Diseases (91) · Lipid Metabolism Disorders (90) · Metabolism, Inborn Errors (90) · Genetic Diseases, Inborn (89) · Lipid Metabolism, Inborn Errors (89) · Metabolic Diseases (89) · Dyslipidemias (87) · Hypoalphalipoproteinemias (66) · Behavior (20) · Feeding Behavior (17) · Cardiovascular Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Vascular Diseases (9)
Diet Therapy (3) · Lisinopril (3) · Metformin (3) · Niacin (3) · dapagliflozin (3) · Acetaminophen (2) · Doxycycline (2) · Etodolac (2) · Exercise (2) · Morphine (2) · Olanzapine (2) · Ondansetron (2) · Rosuvastatin Calcium (2) · Tablets (2) · Tramadol (2)
IPCA Laboratories Ltd. (12) · Par Pharmaceutical, Inc. (11) · Dr. Reddy's Laboratories Limited (7) · National Heart, Lung, and Blood Institute (NHLBI) (5) · Pfizer (4) · Isfahan University of Medical Sciences (3) · Nantes University Hospital (3) · Actavis Inc. (2) · AstraZeneca (2) · Bristol-Myers Squibb (2) · Geropharm (2) · Hospices Civils de Lyon (2) · University of Pennsylvania (2) · Aga Khan University (1) · Atlantic Health System (1)
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Dr. Hardik Dave, M.B.B.S. (2) · Dr. Rupesh Vala, M.B.B.S. (2) · Dr. Suhas Khandave, M.D. (2) · Dr. Tarang Shah, M.D. (2) · Eric Masson, Pharm.D. (2) · Leila Azadbakht, PhD (2) · Marina Cuchel, MD, PhD (2) · Robert D Shamburek, M.D. (2) · Alan S. Marion, MD, PhD (1) · Alpeshkumar Patel, MD (1) · Andrei C Sposito, PhD (1) · Andy Darma, Paediatrician (1) · Anthony R Godfrey, Pharm.D. (1)
PMID 12485966, PMID 16818923, PMID 17384344, PMID 18201934, PMID 20008831, PMID 22775199, PMID 23713767, PMID 23986778, PMID 24279738, PMID 24768191, PMID 25527677, PMID 25559009, PMID 26179237, PMID 26330422, PMID 26499033, PMID 26628614, PMID 26661397, PMID 27050191, PMID 27548405, PMID 27807041, PMID 28204912, PMID 29080546, PMID 30021760, PMID 30997650, PMID 32865503, PMID 33598473, PMID 34763335, PMID 34886337, PMID 34969419, PMID 35061234, PMID 35068165, PMID 35861827, PMID 35871953, PMID 36480560, PMID 38375072, PMID 38726886, PMID 39128497, PMID 39641169, PMID 39886351, PMID 39968784, PMID 39982630, PMID 41823253, PMID 42087898, PMID 9018491
2005 (1), 2016 (1), 2023 (1), R01HL033973 (1), R01HL056895 (1), R56HL118343 (1)