266 completed, 51 unknown, 41 recruiting, 25 terminated. 79 Not applicable, 64 Phase 4, 63 Phase 3, 60 Phase 2, 24 Phase 1.
Follow Hyperparathyroidism: new trials by email Literature Review of Hyperparathyroidism trials Research Report on Hyperparathyroidism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) Endothelial cell collection - Obesity and Obesity-related Medical Conditions, Diabetes | Recruiting | Bettina Mittendorfer | 100 | 2027-01-01 | 2026-05-07 | |
| A Study of PLS240 in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis PLS240, Standard of Care - Chronic Kidney Disease (CKD), Secondary Hyperparathyroidism | Phase 3 | Not yet recruiting | Pathalys Pharma | 56 | 2026-10-30 | 2026-10-22 |
| Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism Scheduling Navigation, Without Scheduling Navigation - Hyperparathyroidism, Primary | Not applicable | Recruiting | University of Pennsylvania | 76 | 2026-10-01 | 2026-08-27 |
| Osteoporosis & Renal Disease: Research in Primary Health Care Services Fracture risk assessment tool (FRAX), Dual-Energy X-ray Absorptiometry (DXA) - Osteoporosis, Chronic Kidney Disease Mineral and Bone Disorder | Not yet recruiting | Universidade do Porto | 622 | 2026-10-01 | 2026-09-30 | |
| Hyperparathyroidism and Dialysis Adequacy in Hemodialysis Patients Hyperparathyroidism, Secondary, Kidney Failure, Chronic | Not yet recruiting | Assiut University | 130 | 2026-09-10 | 2026-09-15 | |
| NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperparathyroidism NIRAF-camera - Primary Hyperparathyroidism | Not applicable | Recruiting | The Cleveland Clinic | 80 | 2026-08-31 | 2026-09-11 |
| Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric Participants CTAP101 - CKD Stage 3, CKD Stage 4 | Phase 2 | Recruiting | OPKO Health, Inc. | 40 | 2026-08-05 | 2026-08-20 |
| Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD Low-dose Colchicine at 0.5mg daily, Usual Care - Chronic Kidney Disease Mineral and Bone Disorder, Hypertension | Phase 2 | Not yet recruiting | University of Texas Southwestern Medical Center | 60 | 2026-07-01 | 2026-06-22 |
| Medium Cut-Off and High-Flux Membranes on Mineral and Bone Metabolism in Hemodialysis Patients Medium Cut-Off Hemodialysis Membrane, High-Flux Hemodialysis Membrane - End Stage Kidney Disease (ESKD), Hemodialysis | Not applicable | Active not recruiting | Gazi University | 30 | 2026-07-01 | 2026-09-14 |
| Shortwave Infrared Surgical Imaging Device Study Observational study of SWIR imaging device in surgery - Cholecystitis, Cholecystitis, Chronic | Enrolling by invitation | Cision Vision, Inc. | 50 | 2026-05-29 | 2026-08-04 | |
| Calcium Isotope Ratios to Assess Calcium Bone Balance in Dialysis Children Receiving Cinacalcet Supplementary blood samples and urines samples - Children Over 3 Undergoing Dialysis With Secondary Hyperparathyroidism | Recruiting | Hospices Civils de Lyon | 20 | 2026-04-29 | 2026-05-22 | |
| Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors 18F-FCH, NeuroEXPLORER - Primary Hyperparathyroidism, Parathyroid Cancer | Phase 2 / Phase 3 | Recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 193 | 2026-04-16 | 2026-06-02 |
| Parathyroidectomy After Kidney Transplantation Subtotal Parathyroidectomy, Conservative Management - Hyperparathyroidism, Kidney Transplantation Recipients | Not applicable | Recruiting | Aarhus University Hospital | 85 | 2026-03-03 | 2026-06-26 |
| Aldosterone Variations in Patients With Primary Hyperparathyroidism After Surgery Primary Hyperparathyroidism, Primary Hyperparathyroidism Due to Adenoma | Not yet recruiting | Central Hospital, Nancy, France | 400 | 2026-02-01 | 2026-02-05 | |
| The CPH-MBD Cohort Chronic Kidney Disease Mineral and Bone Disorder, Chronic Kidney Disease (CKD) | Recruiting | Herlev Hospital | 1000 | 2026-01-07 | 2026-09-16 | |
| Evaluation of the Role of Luteinizing Hormone (LH) and Human Chorionic Gonadotropin (hCG) in Adult Patients Undergoing Assessment for Endocrine Disorders Osteoporosis, Hypercalcemia | Recruiting | Martin Blomberg Jensen | 20000 | 2026-01-01 | 2026-09-17 | |
| The CPH-MBD Cohort Dietary Substudy - Comparison of Methods for Dietary Registrations CKD, Renal Insufficiency Chronic | Recruiting | University of Copenhagen | 50 | 2025-12-15 | 2025-12-31 | |
| The Effect of REgulation of PArathyroId hoRmone in Patients With Chronic Kidney Disease to Investigate the Change in Bone Mineral Density Treat to target - Chronic Kidney Disease Mineral and Bone Disorder | Not applicable | Recruiting | Herlev Hospital | 70 | 2025-11-20 | 2026-01-06 |
| Parathyroid Adenoma Detection With Rubidium-82 Imaging PET/CT imaging with rubidium-82 - Parathyroid Adenomas, Hyperparathyroidism, Primary | Not yet recruiting | Matthieu Pelletier-Galarneau, MD MSc | 20 | 2025-11-01 | 2025-08-22 | |
| Study of MT1013 for the Treatment of Patients With Secondary Hyperparathyroidism MT1013, Cinacalcet - Secondary Hyperparathyroidism, Chronic Kidney Disease | Phase 3 | Recruiting | Shaanxi Micot Pharmaceutical Technology Co., Ltd. | 424 | 2025-09-30 | 2025-10-01 |
Showing 20 of 414. Sign in to see all of them.
Hyperparathyroidism, Secondary (184) · Hyperparathyroidism, Primary (101) · Renal Insufficiency, Chronic (101) · Chronic Kidney Disease-Mineral and Bone Disorder (73) · Kidney Failure, Chronic (50) · Parathyroid Neoplasms (28) · Vitamin D Deficiency (28) · Hypercalcemia (26) · Osteoporosis (24) · Parathyroid Diseases (16) · Bone Diseases, Metabolic (15) · Renal Insufficiency (15) · Kidney Diseases (14) · Hypocalcemia (12)
Endocrine System Diseases (409) · Parathyroid Diseases (398) · Pathological Conditions, Signs and Symptoms (185) · Pathologic Processes (179) · Male Urogenital Diseases (178) · Urogenital Diseases (178) · Female Urogenital Diseases (177) · Female Urogenital Diseases and Pregnancy Complications (177) · Urologic Diseases (177) · Disease Attributes (174) · Chronic Disease (170) · Kidney Diseases (163) · Nutritional and Metabolic Diseases (161) · Metabolic Diseases (147)
Cinacalcet (59) · paricalcitol (35) · Calcitriol (19) · etelcalcetide hydrochloride (18) · 1 alpha-hydroxyergocalciferol (14) · Cholecalciferol (14) · Parathyroidectomy (13) · Vitamin D (12) · Standard of Care (9) · Denosumab (6) · Ergocalciferols (6) · Sevelamer (6) · Calcifediol (5) · alfacalcidol (5) · Blood Specimen Collection (4)
Amgen (43) · Abbott (13) · AbbVie (prior sponsor, Abbott) (12) · Kyowa Kirin Co., Ltd. (10) · Columbia University (8) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (8) · OPKO Health, Inc. (7) · M.D. Anderson Cancer Center (6) · KAI Pharmaceuticals (5) · OPKO IP Holdings II, Inc. (5) · Shanghai Hengrui Pharmaceutical Co., Ltd. (5) · Genzyme, a Sanofi Company (4) · Medical University of Vienna (4) · Shaanxi Micot Pharmaceutical Technology Co., Ltd. (4) · The Cleveland Clinic (4)
United States (134) · China (35) · France (31) · Italy (30) · Denmark (23) · Japan (21) · Germany (20) · Poland (20) · Spain (17) · Russia (16) · Belgium (14) · Canada (14) · Austria (13) · Czechia (13) · Hungary (12)
Joel Melnick, MD (7) · Nancy D. Perrier, MD (5) · Smita Jha, M.D. (4) · M D (3) · Thomas Nickolas, MD, MS (3) · Ann Eldred, MD (2) · Bruno Niederle, Prof., MD (2) · Christos Argyropoulos, MD (2) · Ditte Hansen, MD, PhD (2) · Ditte Hansen, Medical doctor, professor (2) · Dongliang Zhang, Doctor (2) · Efstathios Mitsopoulos, MD (2) · Gregory Bell, MD (2)
PMID 40576086, PMID 40668552, PMID 20943783, PMID 21544866, PMID 27532368, PMID 10654517, PMID 10898180, PMID 11114637, PMID 11114639, PMID 11229970, PMID 11576947, PMID 14668730, PMID 15284307, PMID 15522938, PMID 15663056, PMID 15689407, PMID 15698460, PMID 15711996, PMID 15726399, PMID 15828905, PMID 15930998, PMID 15983958, PMID 16105056, PMID 16540904, PMID 16785355, PMID 16792136, PMID 17071309, PMID 17216827, PMID 17244780, PMID 17284629, PMID 17556697, PMID 17591525, PMID 17666472, PMID 17699221, PMID 17879694, PMID 18178780, PMID 18310602, PMID 18385391, PMID 18397701, PMID 18423809, PMID 18793528, PMID 19018785, PMID 19160424, PMID 19351725, PMID 19365139, PMID 19470620, PMID 19480654, PMID 19776051, PMID 19778452, PMID 19836494
2008 (3), 2023 (3), R01CA212147 (3), 2009 (2), 2018 (2), R01DK032333 (2), R01DK073039 (2), R01DK084986 (2), 2014 (1), 2015 (1), 2016 (1), 2017 (1), K23DK136930 (1), M01RR000042 (1), P30AG028740 (1)