6 completed, 1 not yet recruiting, 1 unknown, 1 withdrawn. 9 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 6, Not yet recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 1, Not yet recruiting 1, Unknown 1, Withdrawn 1 |
Follow Hypercalcemia: new trials by email Literature Review of Hypercalcemia trials Research Report on Hypercalcemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The GranStone Trial empagliflozin (Jardiance) 25 mg, Losartan 100 mg - Paraffinoma, Granuloma, Foreign-Body | Phase 2 / Phase 3 | Not yet recruiting | Martin Blomberg Jensen | 100 | 2026-09-01 | 2026-09-18 |
| Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers Vitamin D, Placebo - Asthma, Asthma Exacerbations | Phase 3 | Completed | Professor Francine Ducharme | 323 | 2018-10-01 | 2025-06-03 |
| ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study ACTHAR Gel (adrenocorticotropic hormone) - Sarcoidosis, Hypercalcemia Due to Sarcoidosis | Phase 2 / Phase 3 | Unknown | Albany Medical College | 10 | 2015-02-01 | 2015-01-26 |
| An Intra-individual Titration Study of KRN1493 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Intractable Primary Hyperparathyroidism Cinacalcet HCl - Parathyroid Carcinoma, Hypercalcemia | Phase 3 | Completed | Kyowa Kirin Co., Ltd. | 2011-11-01 | 2017-03-03 | |
| Primary Hyperparathyroidism (PHPT): Early Effect of Vitamin D Placebo, Vitamin D3 - Primary Hyperparathyroidism, Hypercalcemia | Phase 2 / Phase 3 | Withdrawn | Columbia University | 2010-05-01 | 2015-03-05 | |
| Efficacy and Safety Study of Cinacalcet for the Treatment of Hypercalcemia in Patients With Primary Hyperparathyroidism Unable to Undergo Parathyroidectomy Cinacalcet, Placebo - Hyperparathyroidism, Primary, Hypercalcemia | Phase 3 | Completed | Amgen | 67 | 2010-03-10 | 2018-10-17 |
| Treatment of Autonomous Hyperparathyroidism in Post Renal Transplant Recipients Cinacalcet, Placebo - Chronic Allograft Nephropathy, Chronic Kidney Disease | Phase 3 | Completed | Amgen | 114 | 2009-12-03 | 2018-10-17 |
| Effect of Vitamin D Treatment in Primary Hyperparathyroidism Cholecalciferol - Vitamin D Deficiency, Primary Hyperparathyroidism | Phase 2 / Phase 3 | Completed | University of Aarhus | 46 | 2008-05-01 | 2013-11-18 |
| Cinacalcet to Treat Familial Primary Hyperparathyroidism Parathyroid hormone testing, Serum calcium testing - Hypercalcemia, Familial Primary Hyperparathyroidism | Phase 3 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 25 | 2006-05-09 | 2017-07-02 |
Hyperparathyroidism, Primary (4) · Hypercalciuria (2) · Nephrocalcinosis (2) · Nephrolithiasis (2) · Renal Insufficiency, Chronic (2) · Vitamin D Deficiency (2) · Asthma (1) · Bone Diseases, Metabolic (1) · Carcinoma, Medullary (1) · Gastrinoma (1) · Glomerulonephritis (1) · Granuloma, Foreign-Body (1) · Hyperparathyroidism (1) · Hyperparathyroidism 1 (1)
Calcium Metabolism Disorders (9) · Metabolic Diseases (9) · Nutritional and Metabolic Diseases (9) · Water-Electrolyte Imbalance (9) · Endocrine System Diseases (6) · Parathyroid Diseases (5) · Hyperparathyroidism (4) · Pathological Conditions, Signs and Symptoms (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Male Urogenital Diseases (3) · Pathologic Processes (3) · Urogenital Diseases (3) · Urologic Diseases (3) · Avitaminosis (2)
Cholecalciferol (3) · Cinacalcet (3) · Vitamin D (2) · Adrenocorticotropic Hormone (1) · Losartan (1) · empagliflozin (1)
Amgen (2) · Albany Medical College (1) · Columbia University (1) · Kyowa Kirin Co., Ltd. (1) · Martin Blomberg Jensen (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Professor Francine Ducharme (1) · University of Aarhus (1)
United States (5) · Canada (3) · Australia (2) · Denmark (2) · Poland (2) · Austria (1) · Belgium (1) · France (1) · Germany (1) · Hungary (1) · Italy (1) · Japan (1) · Portugal (1) · Russia (1) · Spain (1)
Francine M Ducharme, MD (1) · Lars Rejnmark, MD,PhD,DrMed (1) · Lars Rolighed, MD (1) · Marc A Judson, MD (1) · Martin B Jensen, Professor (1) · Shonni J. Silverberg, MD (1)
PMID 35018442, PMID 41966354, PMID 42871976
R01DK084986 (1)