2 recruiting, 1 not yet recruiting. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Recruiting 2, Not yet recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow HPV-Negative Squamous Cell Carcinoma: new trials by email Literature Review of HPV-Negative Squamous Cell Carcinoma trials Research Report on HPV-Negative Squamous Cell Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) Hypofractionated Stereotactic Body Radiotherapy (SBRT), Pembrolizumab, Ficerafusp alfa - Head and Neck Squamous Cell Carcinoma, HPV-Negative Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Washington University School of Medicine | 45 | 2026-09-30 | 2026-08-13 |
| Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer Biospecimen Collection, Chemotherapy, Decitabine - Human Papillomavirus-Negative Neck Squamous Cell Carcinoma, Resectable Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | Mayo Clinic | 32 | 2026-01-23 | 2026-07-15 |
| Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer Paclitaxel, Carboplatin, Cetuximab - HPV-Negative Squamous Cell Carcinoma | Phase 1 | Recruiting | University of Chicago | 36 | 2023-12-18 | 2025-06-08 |
Carcinoma, Squamous Cell (1) · Head and Neck Neoplasms (1) · Hypopharyngeal Neoplasms (1) · Jaw Neoplasms (1) · Laryngeal Neoplasms (1) · Lip Neoplasms (1) · Mouth Neoplasms (1) · Oropharyngeal Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1) · Tongue Neoplasms (1)
Bone Diseases (1) · Bone Neoplasms (1) · Carcinoma (1) · Jaw Diseases (1) · Laryngeal Diseases (1) · Lip Diseases (1) · Mouth Diseases (1) · Musculoskeletal Diseases (1) · Neoplasms (1) · Neoplasms by Histologic Type (1) · Neoplasms by Site (1) · Neoplasms, Glandular and Epithelial (1) · Neoplasms, Squamous Cell (1) · Otorhinolaryngologic Diseases (1) · Otorhinolaryngologic Neoplasms (1)
Radiation (2) · Carboplatin (1) · Cetuximab (1) · Cisplatin (1) · Congresses as Topic (1) · Decitabine (1) · Drug Therapy (1) · Fluorouracil (1) · Hydroxyurea (1) · Injections (1) · Paclitaxel (1) · Specimen Handling (1) · Surgical Procedures, Operative (1) · pembrolizumab (1)
Mayo Clinic (1) · University of Chicago (1) · Washington University School of Medicine (1)
United States (3)
Adam L. Holtzman, MD (1) · Ari Rosenberg, MD (1) · Sana Karam, MD, PhD (1) · Sidharth Puram, MD, PhD (1)