23 completed, 9 unknown, 6 recruiting, 2 active not recruiting. 26 Not applicable, 3 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 4.
Follow High Risk Pregnancy: new trials by email Literature Review of High Risk Pregnancy trials Research Report on High Risk Pregnancy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antenatal High-Risk Pregnancy Intervention Bundle in Rural Nepal High Risk Pregnancy Bundle - High Risk Pregnancy | Not applicable | Not yet recruiting | University of California, San Francisco | 100 | 2026-08-01 | 2026-07-21 |
| Tele-Supported Motor Imagery Exercise in High-Risk Pregnancy Tele-rehabilitation-supported exercise program, Home exercise program - High Risk Pregnancy, Tele-rehabilitation | Not applicable | Recruiting | Izmir University of Economics | 38 | 2026-02-20 | 2026-09-02 |
| Pivotal, Prospective, Multi-centre, Single-arm Study to Evaluate the Safety and Effectiveness of Oli for Identification of Patients, During the Intrapartum Period, Who Are at Higher Risk of Developing Abnormal Postpartum Uterine Bleeding, Including Postpartum Haemorrhage Oli is a non-invasive, wearable device, designed to provide clinicians with an early indication if the participant is at a higher risk of developing abnormal postpartum uterine bleeding - Post Partum Haemorrhage, Maternal Care Patterns | Not applicable | Active not recruiting | Baymatob Operations Pty Ltd | 1000 | 2025-08-06 | 2026-07-01 |
| Remote Fetal Monitoring in High Risk Pregnancies Fetal ECG monitoring - High Risk Pregnancy, Remote Patient Monitoring | Recruiting | Beth Israel Deaconess Medical Center | 50 | 2025-05-01 | 2026-03-09 | |
| Effects of Virtual Reality and Relaxation During Non-Stress Testing Virtual reality glasses, Progressive muscle relaxation exercises - Maternal Anxiety Level, Non Stress Test (NST) | Not applicable | Completed | Istanbul University - Cerrahpasa | 126 | 2025-03-01 | 2026-06-25 |
| Verify the Safety and Effectiveness of the Cerclage Pessary in Prevention and Treatment of High-risk Preterm Pregnancy Progesterone, pessary - High Risk Pregnancy | Not applicable | Not yet recruiting | QH Medical Technology Ltd. | 300 | 2024-12-01 | 2023-11-18 |
| Preventing Obstetric Complications With Dietary Intervention Maternal Health Management Program - Gestational Diabetes, Gestational Hypertension | Not applicable | Active not recruiting | Medical College of Wisconsin | 69 | 2024-06-12 | 2026-07-20 |
| Education of Pregnant Women With a Prenatal Indication for Cesarean Section Through Periodic Short Message Service (SMS) and Interactive Voice Response System (IVR) in Uganda SMS and Interactive Voice Response (IVR) Educational Intervention - High Risk Pregnancy, Cesarean Section | Not applicable | Completed | Massachusetts General Hospital | 71 | 2024-06-11 | 2026-07-10 |
| Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China Twin Pregnancy, Antepartum Condition or Complication, Twin to Twin Transfusion as Antepartum Condition | Recruiting | Peking University Third Hospital | 2000 | 2024-03-01 | 2024-05-16 | |
| Emotional Freedom Technique Emotional Freedom Tecnic - High Risk Pregnancy | Not applicable | Completed | Mersin University | 62 | 2024-03-01 | 2026-02-27 |
| Multiple Micronutrients Supplementation on Angiogenesis and Vasculogenesis Factors, and Fetal Biometry Multiple Micronutrients, Standard Antenatal Vitamin - Angiogenesis, Fetal Weight | Not applicable | Unknown | Dr Cipto Mangunkusumo General Hospital | 200 | 2024-03-01 | 2025-04-16 |
| Efficiency of Autologous Amniotic Fluid Injection in the Healing of Cesarean Section Scar in High-Risk Population autologous amniotic fluid, No amniotic fluid injected in skin edges - High Risk Pregnancy, Healing Surgical Wounds | Phase 4 | Completed | Kasr El Aini Hospital | 108 | 2024-02-16 | 2024-08-01 |
| Continuous Non-invasive Electrophysiological Monitoring in High Risk Pregnancies continuous eCTG monitoring using the NFMS - Perinatal Outcomes, Preterm Birth | Not applicable | Unknown | Maxima Medical Center | 1911 | 2023-11-22 | 2023-12-07 |
| Music Therapy and High-risk Pregnancy Music-therapy - High Risk Pregnancy | Not applicable | Unknown | Istituto Giannina Gaslini | 72 | 2023-06-01 | 2024-02-28 |
| Sleep and Tracking Effects in Pregnancy Study Activity Intervention - Pregnancy Complications, Pregnancy Related | Not applicable | Withdrawn | University of North Carolina, Chapel Hill | 2023-05-01 | 2025-02-10 | |
| The Effect of Virtual Reality and Music in High-Risk Pregnants on Non-Stress Test Virtual Reality, Music - High Risk Pregnancy | Not applicable | Completed | NESLİHAN YILMAZ SEZER | 102 | 2023-01-09 | 2023-05-12 |
| HOME: Home Monitoring of High-risk Pregnancies Home surveillance of pregnancies at risk - Hypertensive Disorder of Pregnancy, Premature Preterm Rupture of Membranes | Enrolling by invitation | Oslo University Hospital | 250 | 2022-11-21 | 2026-02-18 | |
| Carbetocin Versus Oxytocin for Prophylaxis Against Atonic Primary Post-partum Hemorrhage Oxytocin, Carbetocin - Atonic Postpartum Hemorrhage, High Risk Pregnancy | Not applicable | Unknown | Sohag University | 80 | 2022-07-28 | 2022-08-02 |
| Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial Metformin - Preeclampsia, Preeclampsia Severe | Not applicable | Unknown | Hamad Medical Corporation | 414 | 2022-03-24 | 2022-03-29 |
| Early Prediction of Preeclampsia Using arteriaL Stiffness in High-risk prEgnancies Arterial Stiffness and Wave Reflection - High Risk Pregnancy, Arterial Stiffness | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2400 | 2021-07-12 | 2025-04-18 |
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Pre-Eclampsia (7) · Premature Birth (5) · Postpartum Hemorrhage (4) · Pregnancy Complications (3) · Anxiety Disorders (2) · Fetal Death (2) · Perinatal Death (2) · Sexual Dysfunction, Physiological (2) · Stillbirth (2) · Abortion, Spontaneous (1) · Abruptio Placentae (1) · Body-Weight Trajectory (1) · Brugada Syndrome (1) · Communication (1) · Congenital Abnormalities (1)
Urogenital Diseases (22) · Female Urogenital Diseases and Pregnancy Complications (20) · Pregnancy Complications (17) · Obstetric Labor Complications (10) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (7) · Hypertension, Pregnancy-Induced (6) · Obstetric Labor, Premature (5) · Hemorrhage (4) · Puerperal Disorders (4) · Uterine Hemorrhage (4) · Behavior (3) · Cardiovascular Diseases (3) · Death (3) · Genital Diseases (3)
Oxytocin (3) · Music Therapy (2) · carbetocin (2) · Ambulatory Care Facilities (1) · Arginine (1) · Aspirin (1) · Certolizumab Pegol (1) · Imagery, Psychotherapy (1) · Magnetic Resonance Imaging (1) · Metformin (1) · Misoprostol (1) · Pessaries (1) · Pregnancy, High-Risk (1) · Progesterone (1) · Sildenafil Citrate (1)
Medical College of Wisconsin (2) · University of North Carolina, Chapel Hill (2) · Ain Shams University (1) · Baymatob Operations Pty Ltd (1) · Beth Israel Deaconess Medical Center (1) · Center For Maternal Fetal Medicine (1) · David Ware Branch (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Dr Cipto Mangunkusumo General Hospital (1) · Fayoum University Hospital (1) · Hamad Medical Corporation (1) · Hawler Medical University (1) · Istanbul University - Cerrahpasa (1) · Istituto Giannina Gaslini (1) · Izmir University of Economics (1)
United States (19) · Turkey (Türkiye) (7) · Egypt (3) · Canada (2) · China (2) · Australia (1) · Germany (1) · Indonesia (1) · Iraq (1) · Israel (1) · Italy (1) · Mexico (1) · Nepal (1) · Netherlands (1) · Norway (1)
Tracy A Manuck, MD (2) · Adeline A Boatin, MD MPH (1) · Ahmed T Ahmed, MD (1) · Allison Dempsey, PhD (1) · Amr O Abdelkareem, MD (1) · Anju Ranjit, MD MPH (1) · Anna Palatnik, MD (1) · Anne Cathrine Staff, MD, PhD (1) · Antonio Frias, MD (1) · Archana Shrestha (1) · Ashraf F Nabhan, Professor (1) · Bara Al Jarrah, BSE (1) · Chro S. Hassan, MBChB (1) · D. Ware Branch, MD (1)
PMID 11803092, PMID 21519036, PMID 22362253, PMID 24222334, PMID 27871953, PMID 32857893, PMID 33944668, PMID 35853003, PMID 36453699, PMID 36593702, PMID 37140175, PMID 37806650, PMID 38190051, PMID 40726590, PMID 41224309, PMID 41692770, PMID 41896782, PMID 42528920
R01HL143485 (1), U01HD087182 (1)