12 recruiting. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Recruiting 12 |
Follow Headache Disorders, Primary: new trials by email Literature Review of Headache Disorders, Primary trials Research Report on Headache Disorders, Primary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Find Out if the Medicine Called Rimegepant is Safe for Adults in India Rimegepant 75 mg ODT - Acute Treatment of Migraine | Phase 4 | Recruiting | Pfizer | 60 | 2026-07-24 | 2026-10-15 |
| Treatment of Tension-type Headache by Zhixuan Analgesic Tablets Zhixuan Analgesic Tablet, Placebo - Frequent Episodic Tension-Type Headache | Phase 4 | Recruiting | Tongji Hospital | 212 | 2026-01-01 | 2026-10-14 |
| Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US Rimegepant 75 MG - Migraine, Trigger Induced Migraine | Phase 4 | Recruiting | Medstar Health Research Institute | 60 | 2025-09-09 | 2025-12-24 |
| Evaluation of Efficacy and Safety of Topical Cannabidiol (Canvert-M Produced by Alasht Pharmed co. Iran) in the Treatment of Migraine Attacks Canvert-M (Produced by Alasht Pharmed co. Iran) - Migraine Disorders | Phase 4 | Recruiting | Alasht Pharmed | 30 | 2025-07-16 | 2025-07-30 |
| Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study Atogepant 60 mg, Propranolol 160 mg, Topiramate 100 mg - Migraine | Phase 4 | Recruiting | Mayo Clinic | 1335 | 2025-07-09 | 2026-10-19 |
| A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache Rimegepant, Rizatriptan Benzoate - Migraine | Phase 4 | Recruiting | Antonios Likourezos | 80 | 2024-09-01 | 2026-09-24 |
| Impact of Combined Oral Contraceptive Pills on Migraine Combined oral contraceptive, Vaginal Ring - Migraine | Phase 4 | Recruiting | Kafrelsheikh University | 400 | 2024-07-15 | 2024-10-09 |
| Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications Zavegepant - Migraine | Phase 4 | Recruiting | Mayo Clinic | 200 | 2024-03-22 | 2026-09-17 |
| Migraine and High Flow Oxygenotherapy at the Emergency Department (MiOx) oxygenotherapy, placebo air aerosol - Migraine | Phase 4 | Recruiting | Centre Hospitalier Universitaire de Nice | 70 | 2023-10-01 | 2024-11-18 |
| Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals Caffeine (200 mg), triptans, NSAID (Nonsteroidal anti-inflammatory drugs) - Migraine, Migraine Disease | Phase 4 | Recruiting | Ain Shams University | 120 | 2023-04-26 | 2025-06-15 |
| Treatment of Meniere's Disease With Migraine Medications nortriptyline + topiramate - Ménière | Phase 4 | Recruiting | University of California, Irvine | 40 | 2022-08-01 | 2026-06-22 |
| Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old Qudexy XR, Placebo - Migraine Disorders | Phase 4 | Recruiting | Upsher-Smith Laboratories | 132 | 2021-02-19 | 2025-01-27 |
Migraine Disorders (11) · Headache (2) · Meniere Disease (1) · Migraine with Aura (1) · Tension-Type Headache (1)
Brain Diseases (12) · Central Nervous System Diseases (12) · Headache Disorders (12) · Nervous System Diseases (12) · Neurologic Manifestations (2) · Pain (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Ear Diseases (1) · Endolymphatic Hydrops (1) · Labyrinth Diseases (1) · Otorhinolaryngologic Diseases (1)
rimegepant sulfate (3) · Topiramate (2) · Acetaminophen (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Caffeine (1) · Contraceptive Devices, Female (1) · Contraceptives, Oral, Combined (1) · Nortriptyline (1) · Propranolol (1) · Tryptamines (1) · atogepant (1) · rizatriptan (1)
Mayo Clinic (2) · Ain Shams University (1) · Alasht Pharmed (1) · Antonios Likourezos (1) · Centre Hospitalier Universitaire de Nice (1) · Kafrelsheikh University (1) · Medstar Health Research Institute (1) · Pfizer (1) · Tongji Hospital (1) · University of California, Irvine (1) · Upsher-Smith Laboratories (1)
United States (6) · Egypt (2) · China (1) · France (1) · India (1) · Iran (1)
Hamid Djalilian, MD (1) · Jessica Ailani, MD (1) · Sergey Motov, MD (1) · Todd J Schwedt, M.D. (1) · Todd Schwedt, MD (1)
PMID 11914403, PMID 12807523, PMID 29248887, PMID 33069326, PMID 8984084