4 active not recruiting. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 4 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Fibrosarcoma: new trials by email Literature Review of Fibrosarcoma trials Research Report on Fibrosarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma Definitive Surgical Resection, Nanoplexed Poly I:C BO-112, Nivolumab - Leiomyosarcoma, Malignant Peripheral Nerve Sheath Tumor | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 14 | 2020-10-14 | 2026-03-10 |
| B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults second generation 4-1BBζ B7H3-EGFRt-DHFR, second generation 4-1BBζ B7H3-EGFRt-DHFR(selected) and a second generation 4-1BBζ CD19-Her2tG, Pembrolizumab - Pediatric Solid Tumor, Germ Cell Tumor | Phase 1 | Active not recruiting | Seattle Children's Hospital | 68 | 2020-07-13 | 2026-04-28 |
| EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults second generation 4-1BBζ EGFR806-EGFRt, second generation 4-1BBζ EGFR806-EGFRt and a second generation 4 1BBζ CD19-Her2tG - Pediatric Solid Tumor, Germ Cell Tumor | Phase 1 | Active not recruiting | Seattle Children's Hospital | 44 | 2019-06-18 | 2026-10-08 |
| A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors Phase 1b: APG-115+pembrolizumab - Unresectable or Metastatic Melanoma or Advanced Solid Tumors, Melanoma | Phase 1 / Phase 2 | Active not recruiting | Ascentage Pharma Group Inc. | 230 | 2018-08-29 | 2025-08-07 |
Neurofibrosarcoma (4) · Sarcoma (3) · Sarcoma, Synovial (3) · Carcinoma (2) · Desmoplastic Small Round Cell Tumor (2) · Hepatoblastoma (2) · Melanoma (2) · Neoplasms, Germ Cell and Embryonal (2) · Neuroblastoma (2) · Osteosarcoma (2) · Retinoblastoma (2) · Rhabdoid Tumor (2) · Rhabdomyosarcoma (2) · Sarcoma, Clear Cell (2) · Sarcoma, Ewing (2)
Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms, Connective Tissue (4) · Neoplasms, Connective and Soft Tissue (4) · Neoplasms, Fibrous Tissue (4) · Neoplasms, Nerve Tissue (4) · Nerve Sheath Neoplasms (4) · Nervous System Diseases (4) · Nervous System Neoplasms (4) · Neurofibroma (4) · Neuromuscular Diseases (4) · Peripheral Nervous System Diseases (4) · Peripheral Nervous System Neoplasms (4) · Eye Diseases (3)
pembrolizumab (2) · BO-112 (1) · Nivolumab (1) · Radiation (1) · Radiotherapy (1)
Seattle Children's Hospital (2) · Ascentage Pharma Group Inc. (1) · Jonsson Comprehensive Cancer Center (1)
United States (4) · Australia (1)
Catherine Albert, MD (1) · Katie Albert, MD (1) · Vishruth Reddy, MD, PhD (1) · Yifan Zhai, MD, PhD (1)
K08CA245181 (1)