11 completed, 2 recruiting, 2 unknown. 5 Not applicable, 3 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 4, Unknown 1 |
| Phase 4 | 3 | Completed 3 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Extracorporeal Circulation: new trials by email Literature Review of Extracorporeal Circulation trials Research Report on Extracorporeal Circulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clindamycin as an Alternative to Vancomycin in Patients Undergoing Aortic Cardiac Surgery With Extracorporeal Circulation (ECC) Clindamycin - Aortic Surgery, Extracorporeal Circulation | Phase 2 | Recruiting | Nantes University Hospital | 25 | 2026-04-21 | 2026-04-28 |
| Impact of VARIation of OXYdo-reduction Potential in Cardiac Surgery on Post-operative Outcome Blood and tissue samples, walking test - Cardiac Surgery, Extracorporeal Circulation | Recruiting | University Hospital, Toulouse | 120 | 2025-10-07 | 2026-06-29 | |
| Biocompatible Versus Non-coated Extracorporeal Circuits in Cardiac Surgery Cardiac surgery with the use of extracorporeal circulation - Cardiac Surgery Requiring Cardiopulmonary Bypass, Extracorporeal Circulation | Not applicable | Completed | Polychronis Antonitsis | 50 | 2024-04-01 | 2025-05-28 |
| Interchangeability of Arterial Coagulation and Venous Coagulation, in the Context of Cardiac Surgeries Under Cardiopulmonary Bypass, Using the DMDiv Hemochron Signature Elite interchangeability of arterial or venous hemostasis - Hemostasis, Extracorporeal Circulation | Completed | Centre Hospitalier Universitaire, Amiens | 201 | 2023-06-07 | 2026-06-25 | |
| Evaluation of Systemic Microcirculation of Patients Undergoing Heart Valve Surgery Evaluation of sublingual microcirculation with side-stream dark field imaging (cytocam) - Microvascular Rarefaction, Heart Valve Diseases | Completed | National Institute of Cardiology, Laranjeiras, Brazil | 31 | 2022-09-10 | 2025-05-21 | |
| Anticoagulation Management in Complex Cardiac Surgery Activated Clotting Time measurements combined with heparin concentration monitoring, Activated Clotting Time - Extracorporeal Circulation | Phase 4 | Completed | Aristotle University Of Thessaloniki | 65 | 2021-01-01 | 2023-07-14 |
| Cytokine Adsorption in Post-cardiac Arrest Syndrome in Patients Requiring Extracorporeal Cardiopulmonary Resuscitation Cytosorb removal column in eCPR, standard eCPR (va-ECMO) - Cardiac Arrest, Extracorporeal Circulation | Not applicable | Completed | University Hospital Freiburg | 41 | 2019-09-25 | 2021-03-15 |
| Removal of Cytokines in Patients Undergoing Cardiac Surgery With CPB Cytosorb Adsorber - Extracorporeal Circulation, Hemofiltration | Not applicable | Unknown | Klinikum Nürnberg | 80 | 2017-05-01 | 2017-04-07 |
| Observational Study About the Use of Fibrinogen in Adult Cardiac Surgery Cardiac Surgery, Extracorporeal Circulation | Unknown | Société Française d'Anesthésie et de Réanimation | 3000 | 2017-03-01 | 2017-03-09 | |
| Priming of Cardiopulmonary Bypass With Hydroxyethyl Starch 130/0.4 or Sodium Chloride 0.9% : Pilot Study in Adult Elective Conventional Cardiac Surgery Non balanced Hydroxyethyl starch 130/0.4 (Voluven®, Fresenius), Sodium Chloride 0.9% (Fresenius) - Extracorporeal Circulation, Cardiac Surgery | Phase 3 | Completed | Hospices Civils de Lyon | 30 | 2016-12-06 | 2025-08-06 |
| Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass Non-invasive blood pressure oscillometer (NIBP) implementation - Cardiopulmonary Bypass, Cardiac Surgery | Not applicable | Completed | Hospices Civils de Lyon | 40 | 2016-01-01 | 2025-09-09 |
| RRI Compared With NephroCheckTM to Predict Acute Renal Failure After Cardiac Surgery. Renal Resistive Index compared with NephroCheckTM - Cardiac Surgery, Extracorporeal Circulation | Completed | University Hospital, Bordeaux | 51 | 2014-09-01 | 2015-11-02 | |
| Rheoparin-coated Tubing System for Minimized Extracorporeal Circulation (MECC) MECC system with rheoparin coating - Extracorporeal Circulation, Inflammation | Not applicable | Completed | Insel Gruppe AG, University Hospital Bern | 50 | 2013-04-01 | 2019-12-19 |
| Cerebral Embolic Load in Patients Undergoing Surgical Aortic Valve Replacement: A Comparison of the Conventional With the Minimized Extracorporeal Circulation Technique Using Transcranial Doppler Ultrasound Minimized Extracorporeal Circulation (MECC), Conventional Extracorporeal Circulation (CECC) - Aortic Valve Stenosis, Extracorporeal Circulation | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 48 | 2011-06-01 | 2016-06-30 |
| Coronary Bypass and Artotic Leaflet Surgery : Heparin Low Dose vs Full Dose Heparin Low Dose, Heparin Full Dose - Cardiac Surgery, Extracorporeal Circulation | Phase 4 | Completed | University Hospital, Bordeaux | 238 | 2008-06-01 | 2026-05-19 |
Inflammation (2) · Intracranial Embolism (2) · Thrombosis (2) · Aortic Valve Stenosis (1) · Cytokine Release Syndrome (1) · Heart Arrest (1) · Heart Valve Diseases (1) · Hemorrhage (1) · Microvascular Rarefaction (1) · Post-Cardiac Arrest Syndrome (1) · Renal Insufficiency (1)
Cardiovascular Diseases (5) · Pathological Conditions, Signs and Symptoms (4) · Vascular Diseases (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Embolism and Thrombosis (3) · Heart Diseases (3) · Nervous System Diseases (3) · Pathologic Processes (3) · Cerebrovascular Disorders (2) · Intracranial Embolism and Thrombosis (2) · Thromboembolism (2) · Aortic Valve Disease (1) · Brain Injuries (1) · Female Urogenital Diseases (1)
Blood Specimen Collection (1) · Cardiac Surgical Procedures (1) · Clindamycin (1) · HES 130-0.4 (1) · Heparin (1) · Sodium Chloride (1)
Hospices Civils de Lyon (2) · Insel Gruppe AG, University Hospital Bern (2) · University Hospital, Bordeaux (2) · Aristotle University Of Thessaloniki (1) · Centre Hospitalier Universitaire, Amiens (1) · Klinikum Nürnberg (1) · Nantes University Hospital (1) · National Institute of Cardiology, Laranjeiras, Brazil (1) · Polychronis Antonitsis (1) · Société Française d'Anesthésie et de Réanimation (1) · University Hospital Freiburg (1) · University Hospital, Toulouse (1)
France (7) · Germany (2) · Greece (2) · Switzerland (2) · Brazil (1)
Thierry Carrel, MD, PhD (2) · Daniel Duerschmied, Prof. Dr. (1) · Helena Argiriadou, Dr (1) · Isaak Keremidis, MScP (1) · Kali Makedou, MD, PhD (1) · Polychronis Antonitsis, MD, PhD (1) · Theodora Papamitsou, MD, PhD (1)
PMID 31138465, PMID 35143902, PMID 39373400, PMID 41286643
2025 (1)