11 completed. 11 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Completed 11 |
| Phase 1 | 2 | Completed 2 |
Follow Ewing's Sarcoma: new trials by email Literature Review of Ewing's Sarcoma trials Research Report on Ewing's Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma Vigil, Temozolomide, Irinotecan - Ewing's Sarcoma | Phase 2 | Completed | Gradalis, Inc. | 22 | 2016-02-10 | 2022-12-22 |
| Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors nab-paclitaxel - Neuroblastoma, Rhabdomyosarcoma | Phase 1 / Phase 2 | Completed | Celgene | 107 | 2013-12-04 | 2019-12-27 |
| Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcoma Olaparib - Ewing's Sarcoma | Phase 2 | Completed | Massachusetts General Hospital | 12 | 2012-05-01 | 2017-05-19 |
| Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI Feraheme, Magnetic Resonance Imaging (MRI) scan - Bone Cancer, Chondrosarcoma | Phase 2 | Completed | Heike E Daldrup-Link | 32 | 2011-08-01 | 2023-12-27 |
| Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy Zalypsis - Ewing's Sarcoma, Primitive Neuroectodermal Tumor (PNET) | Phase 2 | Completed | PharmaMar | 17 | 2010-12-01 | 2021-10-29 |
| Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young Adults Chemotherapy, Surgery, Radiotherapy - Ewing's Sarcoma | Phase 2 | Completed | Grupo Espanol de Investigacion en Sarcomas | 43 | 2010-03-30 | 2018-08-01 |
| QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors AMG 479 - Askin's Tumors, Desmoplastic Small Round Cell Tumors | Phase 2 | Completed | NantCell, Inc. | 38 | 2007-10-01 | 2016-10-27 |
| Aerosol L9-NC and Temozolomide in Ewing's Sarcoma Temozolomide, L9-NC - Ewing's Sarcoma | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 10 | 2006-06-01 | 2012-08-02 |
| A Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 With or Without Autologous T Cell Transplantation in Recurrent Pediatric Sarcomas EF-1 Peptide, EF-2 Peptide, PXFK Peptide - Ewing's Sarcoma, Rhabdomyosarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 30 | 1996-12-23 | 2019-11-29 |
| A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas therapeutic autologous dendritic cells, indinavir sulfate, peripheral blood stem cell transplantation - Ewing's Sarcoma, Rhabdomyosarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 42 | 1996-12-01 | 2012-06-15 |
| New Therapeutic Strategies for Patients With Ewing's Sarcoma Family of Tumors, High Risk Rhabdomyosarcoma, and Neuroblastoma ADR-529, Topotecan, G-CSF - Ewing's Sarcoma, Neuroblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 90 | 1993-04-01 | 2008-03-04 |
Sarcoma, Ewing (11) · Rhabdomyosarcoma (5) · Sarcoma (3) · Neuroblastoma (2) · Neuroectodermal Tumors, Primitive (2) · Osteosarcoma (2) · Askin Tumor (1) · Bone Neoplasms (1) · Chondrosarcoma (1) · Dermatofibrosarcoma (1) · Fibrosarcoma (1) · Histiocytoma (1) · Insulin-Like Growth Factor I, Resistance To (1) · Melanoma (1) · Neoplasm Metastasis (1)
Neoplasms by Histologic Type (11) · Neoplasms, Bone Tissue (11) · Neoplasms, Connective Tissue (11) · Neoplasms, Connective and Soft Tissue (11) · Neoplasms (10) · Osteosarcoma (9) · Sarcoma (8) · Myosarcoma (5) · Neoplasms, Muscle Tissue (5) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Neoplasms, Neuroepithelial (4) · Neuroectodermal Tumors (4) · Neoplasms by Site (2)
Temozolomide (2) · 130-nm albumin-bound paclitaxel (1) · Albumin-Bound Paclitaxel (1) · CD40 Ligand (1) · Dexrazoxane (1) · Docetaxel (1) · Drug Therapy (1) · FANG vaccine (1) · Ferrosoferric Oxide (1) · Gemcitabine (1) · Granulocyte Colony-Stimulating Factor (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Indinavir (1) · Interleukin-2 (1) · Interleukin-4 (1)
National Cancer Institute (NCI) (3) · Celgene (1) · Gradalis, Inc. (1) · Grupo Espanol de Investigacion en Sarcomas (1) · Heike E Daldrup-Link (1) · M.D. Anderson Cancer Center (1) · Massachusetts General Hospital (1) · NantCell, Inc. (1) · PharmaMar (1)
United States (9) · France (2) · Italy (2) · Spain (2) · Canada (1) · Switzerland (1) · United Kingdom (1)
Armando Santoro, Prof. (1) · Crystal L Mackall, M.D. (1) · Crystal Mackall, M.D. (1) · Cynthia E. Herzog, MD (1) · Edwin Choy, MD PhD (1) · Fariba Navid, MD (1) · Heike E Daldrup-Link, MD (1) · Ileana Elias, M.D. (1) · Jaume Mora Graupera, MD (1) · Jean Yves Blay, MD (1) · John Nemunaitis, MD (1) · Neyssa Marina, MD (1) · Paolo Casali, MD (1) · Robin L. Jones, MD (1)
PMID 18676758, PMID 25374341, PMID 31401903, PMID 32554315
2009 (1)