8 completed, 1 terminated, 1 unknown. 10 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 8, Terminated 1, Unknown 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Ewing's Sarcoma: new trials by email Literature Review of Ewing's Sarcoma trials Research Report on Ewing's Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803 Natural Killer (NK) Cells, ALT803 - Acute Myeloid Leukemia, Myelodysplastic Syndrome | Phase 1 | Completed | Brenda Cooper, MD | 14 | 2018-05-22 | 2023-02-21 |
| Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma pbi-shRNA™ EWS/FLI1 Type 1 Lipoplex - Ewing's Sarcoma, Ewing Family of Tumors | Phase 1 | Completed | Gradalis, Inc. | 7 | 2016-10-01 | 2023-11-13 |
| Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors nab-paclitaxel - Neuroblastoma, Rhabdomyosarcoma | Phase 1 / Phase 2 | Completed | Celgene | 107 | 2013-12-04 | 2019-12-27 |
| Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors sirolimus - Ewing's Sarcoma, Osteosarcoma | Phase 1 | Completed | Emory University | 18 | 2011-04-01 | 2020-05-29 |
| Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides racotumomab - Neuroblastoma, Ewing's Sarcoma | Phase 1 | Completed | Laboratorio Elea Phoenix S.A. | 15 | 2011-02-01 | 2015-07-29 |
| Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients Recombinant Vaccinia GM-CSF; RAC VAC GM-CSF (JX-594) - Neuroblastoma, Rhabdomyosarcoma | Phase 1 | Completed | Jennerex Biotherapeutics | 6 | 2010-08-01 | 2016-01-21 |
| HGS-ETR2 to Treat Children With Solid Tumors Lexatumumab alone, Lexatumumab in combination, Interferon gamma 1b in combination - Ewing's Sarcoma, Osteosarcoma | Phase 1 | Terminated | National Cancer Institute (NCI) | 30 | 2006-12-04 | 2019-12-17 |
| Aerosol L9-NC and Temozolomide in Ewing's Sarcoma Temozolomide, L9-NC - Ewing's Sarcoma | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 10 | 2006-06-01 | 2012-08-02 |
| Comparison of Filgrastim and Filgrastim SD/01in Boosting White Cell Counts After Intensive Chemotherapy Filgrastim, Filgrastim-SD/01 - Ewing's Sarcoma, Rhabdomyosarcoma | Phase 1 | Completed | National Cancer Institute (NCI) | 34 | 2000-03-03 | 2019-11-12 |
| Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors High-Dose Chemotherapy with Tandem PBSC Rescue. - Ewing's Sarcoma, Soft Tissue Sarcoma | Phase 1 / Phase 2 | Unknown | Ann & Robert H Lurie Children's Hospital of Chicago | 12 | 1999-04-01 | 2010-10-11 |
Sarcoma, Ewing (10) · Rhabdomyosarcoma (6) · Neuroblastoma (5) · Sarcoma (5) · Osteosarcoma (4) · Wilms Tumor (4) · Neoplasms (3) · Glioma (2) · Hepatoblastoma (2) · Hodgkin Disease (2) · Neoplasms, Germ Cell and Embryonal (2) · Neurofibrosarcoma (2) · Retinoblastoma (2) · Astrocytoma (1) · Bone Neoplasms (1)
Neoplasms by Histologic Type (10) · Neoplasms, Bone Tissue (10) · Neoplasms, Connective Tissue (10) · Neoplasms, Connective and Soft Tissue (10) · Neoplasms (7) · Neoplasms by Site (7) · Neoplasms, Nerve Tissue (7) · Myosarcoma (6) · Neoplasms, Glandular and Epithelial (6) · Neoplasms, Muscle Tissue (6) · Neoplasms, Neuroepithelial (6) · Osteosarcoma (6) · Neoplasms, Germ Cell and Embryonal (5) · Neuroectodermal Tumors (5) · Neuroectodermal Tumors, Primitive (5)
130-nm albumin-bound paclitaxel (1) · ALT-803 (1) · Albumin-Bound Paclitaxel (1) · Cell Count (1) · Cyclophosphamide (1) · Cytokines (1) · Drug Therapy (1) · Filgrastim (1) · Interferon-gamma (1) · Sirolimus (1) · Temozolomide (1) · lexatumumab (1) · pegfilgrastim (1) · racotumomab (1) · rubitecan (1)
National Cancer Institute (NCI) (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Brenda Cooper, MD (1) · Celgene (1) · Emory University (1) · Gradalis, Inc. (1) · Jennerex Biotherapeutics (1) · Laboratorio Elea Phoenix S.A. (1) · M.D. Anderson Cancer Center (1)
United States (9) · Argentina (1) · Canada (1) · France (1) · Italy (1) · Spain (1) · Switzerland (1) · United Kingdom (1)
Crystal L Mackall, M.D. (2) · Cynthia E. Herzog, MD (1) · David Wald, MD, PhD (1) · Guillermo Chantada, MD (1) · Ileana Elias, M.D. (1) · John Nemunaitis, MD (1) · Morris Kletzel, M.D. (1) · Muna Qayed, MD (1) · Timothy Cripe, MD, PhD (1) · Walter Cacciavillano, MD (1)
PMID 23071222, PMID 26154941, PMID 31401903, PMID 31876107, PMID 32554315