10 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 14 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 10, Active not recruiting 1, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Endodermal Sinus Tumor: new trials by email Literature Review of Endodermal Sinus Tumor trials Research Report on Endodermal Sinus Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children sirolimus combined with chemotherapy in the treatment of recurrent/refractory yolk sac tumor in children - Germ Cell Tumor, Yolk Sac Tumor | Phase 2 / Phase 3 | Completed | Shandong First Medical University | 32 | 2020-06-01 | 2025-09-19 |
| Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Best Practice, Biopsy Procedure, Biospecimen Collection - Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma | Phase 3 | Recruiting | Children's Oncology Group | 1780 | 2017-05-25 | 2026-08-25 |
| Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors paclitaxel, ifosfamide, cisplatin - Germ Cell Tumor, Teratoma | Phase 3 | Active not recruiting | Alliance for Clinical Trials in Oncology | 420 | 2015-08-06 | 2026-06-16 |
| Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors cisplatin, ifosfamide, paclitaxel - Extragonadal Germ Cell Tumor, Testicular Germ Cell Tumor | Phase 3 | Terminated | Alliance for Clinical Trials in Oncology | 1 | 2004-04-01 | 2016-07-04 |
| Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors bleomycin sulfate, cisplatin, etoposide - Extragonadal Germ Cell Tumor, Teratoma | Phase 3 | Completed | UNICANCER | 263 | 2003-11-26 | 2025-02-06 |
| Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors conventional surgery, cisplatin, etoposide - Childhood Embryonal Tumor, Childhood Extracranial Germ Cell Tumor | Phase 3 | Completed | Children's Oncology Group | 302 | 2003-11-03 | 2021-07-13 |
| Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment caspofungin acetate, liposomal amphotericin B - Cancer | Phase 3 | Completed | Memorial Sloan Kettering Cancer Center | 2000-08-01 | 2013-01-18 | |
| Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation captopril, cyclophosphamide, autologous bone marrow transplantation - Cancer | Phase 3 | Completed | Northwestern University | 35 | 1999-10-01 | 2012-06-06 |
| Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients liposomal amphotericin B - Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 115 | 1999-06-01 | 2012-09-24 |
| Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer bleomycin sulfate, filgrastim, cisplatin - Mediastinal Cancer, Metastatic Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 222 | 1999-04-01 | 2012-09-24 |
| Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation palivizumab, ribavirin - Cancer | Phase 3 | Completed | Fred Hutchinson Cancer Center | 1999-02-01 | 2010-04-02 | |
| Combination Chemotherapy in Treating Men With Germ Cell Cancer bleomycin sulfate, filgrastim, cisplatin - Extragonadal Germ Cell Tumor, Teratoma | Phase 2 / Phase 3 | Unknown | European Organisation for Research and Treatment of Cancer - EORTC | 498 | 1998-10-01 | 2012-03-06 |
| Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation fluconazole, itraconazole - Cancer | Phase 3 | Completed | Fred Hutchinson Cancer Center | 578 | 1998-10-01 | 2010-04-02 |
| Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors bleomycin sulfate, filgrastim, carboplatin - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 3 | Completed | Memorial Sloan Kettering Cancer Center | 270 | 1994-09-01 | 2013-06-26 |
Teratoma (13) · Carcinoma, Embryonal (11) · Testicular Neoplasms (11) · Seminoma (10) · Teratoma, Testicular (7) · Blast Crisis (5) · Breast Neoplasms (5) · Burkitt Lymphoma (5) · Carcinoma, Ovarian Epithelial (5) · Hodgkin Disease (5) · Leukemia, Hairy Cell (5) · Leukemia, Lymphocytic, Chronic, B-Cell (5) · Leukemia, Myeloid, Accelerated Phase (5) · Leukemia, Myeloid, Acute (5)
Mesonephroma (14) · Neoplasms by Histologic Type (14) · Urogenital Diseases (12) · Endocrine Gland Neoplasms (11) · Endocrine System Diseases (11) · Genital Diseases (11) · Genital Diseases, Male (11) · Genital Neoplasms, Male (11) · Gonadal Disorders (11) · Male Urogenital Diseases (11) · Neoplasms by Site (11) · Neoplasms, Germ Cell and Embryonal (11) · Testicular Diseases (11) · Urogenital Neoplasms (11) · Germinoma (9)
Cisplatin (8) · Etoposide (7) · Bleomycin (6) · Ifosfamide (4) · Paclitaxel (4) · Carboplatin (3) · Filgrastim (3) · Peripheral Blood Stem Cell Transplantation (3) · Cyclophosphamide (2) · Radiotherapy (2) · liposomal amphotericin B (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · Biopsy (1) · Captopril (1) · Caspofungin (1)
European Organisation for Research and Treatment of Cancer - EORTC (3) · Alliance for Clinical Trials in Oncology (2) · Children's Oncology Group (2) · Fred Hutchinson Cancer Center (2) · Memorial Sloan Kettering Cancer Center (2) · Northwestern University (1) · Shandong First Medical University (1) · UNICANCER (1)
United States (10) · Australia (4) · Belgium (4) · France (4) · Germany (4) · Italy (4) · Netherlands (4) · Slovakia (4) · Spain (4) · United Kingdom (4) · Canada (3) · Denmark (3) · Puerto Rico (3) · Switzerland (3) · Austria (2)
Robert J. Motzer, MD (2) · A. L Frazier (1) · Anne Frazier, MD (1) · Darren Feldman, MD (1) · Eric J. Small, MD (1) · Gedske Daugaard, MD, DMSc (1) · Jingfu Wang, MD (1) · Karim Fizazi, MD, PhD (1) · Kent Sepkowitz, MD (1) · Kieren A. Marr, MD (1) · Kim A. Margolin, MD (1) · Leo I. Gordon, MD (1) · Michael Boeckh, MD (1) · P. Ljungman, MD (1) · Patrick J. Loehrer, MD (1)
PMID 15459300, PMID 17235042, PMID 21059637, PMID 25456363, PMID 30563754, PMID 31355926, PMID 37783480, PMID 39028926, PMID 39167741
2005 (1), U10CA031946 (1), U10CA098543 (1), U10CA180821 (1), U10CA180886 (1)