29 completed, 3 recruiting, 2 terminated, 1 unknown. 18 Phase 2, 11 Phase 3, 4 Not applicable, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 18 | Completed 15, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 3 | 11 | Completed 8, Recruiting 1, Terminated 1, Unknown 1 |
| Not applicable | 4 | Completed 4 |
| Phase 1 | 3 | Completed 3 |
Follow Carcinoma, Embryonal: new trials by email Literature Review of Carcinoma, Embryonal trials Research Report on Carcinoma, Embryonal
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Molecular Epidemiology of Pediatric Germ Cell Tumors Questionnaire Administration, Tumor Specimen Collection, Germline DNA Samples - Germ Cell Tumor, Germinoma | Recruiting | Children's Oncology Group | 1151 | 2023-04-12 | 2025-10-24 | |
| A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT Biospecimen Collection, Carboplatin, Etoposide - Central Nervous System Nongerminomatous Germ Cell Tumor, Choriocarcinoma | Phase 2 | Recruiting | Children's Oncology Group | 160 | 2021-07-13 | 2026-09-23 |
| Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Best Practice, Biopsy Procedure, Biospecimen Collection - Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma | Phase 3 | Recruiting | Children's Oncology Group | 1780 | 2017-05-25 | 2026-08-25 |
| Brentuximab Vedotin in Relapsed/Refractory Germ Cell Tumors Brentuximab Vedotin - Germ Cell Tumors, Testis Cancer | Phase 2 | Terminated | Nabil Adra | 18 | 2016-03-09 | 2019-12-10 |
| Brentuximab Vedotin (SGN-35) as Salvage Treatment for CD30-positive Germ Cell Tumors Brentuximab Vedotin - Germ Cell Cancer | Phase 2 | Completed | Fondazione Michelangelo | 9 | 2013-05-01 | 2018-02-07 |
| Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Carboplatin, Filgrastim, Ifosfamide - Childhood Extracranial Germ Cell Tumor, Childhood Extragonadal Malignant Germ Cell Tumor | Phase 2 | Completed | Children's Oncology Group | 20 | 2007-11-05 | 2018-08-29 |
| Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment sunitinib malate - Extragonadal Germ Cell Tumor, Ovarian Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 10 | 2007-03-01 | 2015-10-27 |
| Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors pegfilgrastim, cisplatin, ifosfamide - Brain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 60 | 2007-03-01 | 2017-11-28 |
| Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors carboplatin, etoposide, ifosfamide - Childhood Germ Cell Tumor, Ovarian Cancer | Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 23 | 2006-12-19 | 2022-05-17 |
| Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors bleomycin sulfate, carboplatin, cisplatin - Extragonadal Germ Cell Tumor, Teratoma | Phase 2 | Completed | Medical Research Council | 88 | 2005-06-01 | 2013-08-26 |
| Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors bleomycin sulfate, pegfilgrastim, cisplatin - Extragonadal Germ Cell Tumor, Teratoma | Phase 2 | Completed | Cambridge University Hospitals NHS Foundation Trust | 20 | 2004-08-01 | 2013-08-07 |
| Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors cisplatin, ifosfamide, paclitaxel - Extragonadal Germ Cell Tumor, Testicular Germ Cell Tumor | Phase 3 | Terminated | Alliance for Clinical Trials in Oncology | 1 | 2004-04-01 | 2016-07-04 |
| Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors bleomycin sulfate, cisplatin, etoposide - Extragonadal Germ Cell Tumor, Teratoma | Phase 3 | Completed | UNICANCER | 263 | 2003-11-26 | 2025-02-06 |
| Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors ixabepilone - Brain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 29 | 2003-08-01 | 2013-06-24 |
| Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer ipilimumab, therapeutic allogeneic lymphocytes - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 1 | Completed | National Cancer Institute (NCI) | 21 | 2003-04-01 | 2013-03-27 |
| Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation acupuncture therapy, management of therapy complications, pain therapy - Cancer | Not applicable | Completed | National Cancer Institute (NCI) | 2003-03-01 | 2015-04-30 | |
| Positron Emission Tomography in Detecting Testicle Cancer positron emission tomography, fludeoxyglucose F 18 - Testicular Germ Cell Tumor | Not applicable | Completed | Institute of Cancer Research, United Kingdom | 2002-05-01 | 2013-12-18 | |
| Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment caspofungin acetate, liposomal amphotericin B - Cancer | Phase 3 | Completed | Memorial Sloan Kettering Cancer Center | 2000-08-01 | 2013-01-18 | |
| Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors filgrastim, recombinant interleukin-11 - Breast Cancer, Gestational Trophoblastic Tumor | Phase 2 | Completed | Fred Hutchinson Cancer Center | 2000-08-01 | 2010-04-02 | |
| Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon beclomethasone dipropionate - Breast Cancer, Chronic Myeloproliferative Disorders | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 2000-07-01 | 2010-04-02 |
Showing 20 of 35. Sign in to see all of them.
Endodermal Sinus Tumor (32) · Teratoma (32) · Testicular Neoplasms (32) · Seminoma (25) · Teratoma, Testicular (19) · Testicular Germ Cell Tumor (19) · Breast Neoplasms (14) · Burkitt Lymphoma (14) · Carcinoma, Ovarian Epithelial (14) · Hodgkin Disease (14) · Leukemia, Lymphocytic, Chronic, B-Cell (14) · Lymphoma, Follicular (14) · Lymphoma, Large B-Cell, Diffuse (14) · Lymphoma, Large-Cell, Immunoblastic (14)
Neoplasms by Histologic Type (35) · Urogenital Diseases (34) · Endocrine Gland Neoplasms (32) · Endocrine System Diseases (32) · Genital Diseases (32) · Genital Diseases, Male (32) · Genital Neoplasms, Male (32) · Gonadal Disorders (32) · Male Urogenital Diseases (32) · Mesonephroma (32) · Neoplasms by Site (32) · Testicular Diseases (32) · Urogenital Neoplasms (32) · Neoplasms, Germ Cell and Embryonal (31) · Neoplasms (26)
Cisplatin (10) · Etoposide (9) · Ifosfamide (9) · Filgrastim (8) · Paclitaxel (8) · Bleomycin (7) · Carboplatin (7) · Peripheral Blood Stem Cell Transplantation (4) · Granulocyte Colony-Stimulating Factor (3) · Magnetic Resonance Spectroscopy (3) · Radiotherapy (3) · pegfilgrastim (3) · Brentuximab Vedotin (2) · Cyclophosphamide (2) · Mesna (2)
Fred Hutchinson Cancer Center (7) · Memorial Sloan Kettering Cancer Center (5) · Children's Oncology Group (4) · European Organisation for Research and Treatment of Cancer - EORTC (3) · Medical Research Council (2) · National Cancer Institute (NCI) (2) · Alliance for Clinical Trials in Oncology (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Cancer Treatment Centers of America (1) · City of Hope Medical Center (1) · Eastern Cooperative Oncology Group (1) · Fondazione Michelangelo (1) · Indiana University (1) · Institute of Cancer Research, United Kingdom (1) · Masonic Cancer Center, University of Minnesota (1)
United States (27) · United Kingdom (7) · Australia (4) · Canada (4) · Italy (4) · Slovakia (4) · Belgium (3) · France (3) · Germany (3) · Netherlands (3) · Puerto Rico (3) · Spain (3) · Austria (2) · Denmark (2) · Hungary (2)
Robert J. Motzer, MD (4) · Robert A. Huddart, MD (2) · A. L Frazier (1) · Alessandro M Gianni, MD (1) · Anastasios Raptis, MD (1) · Andrea Necchi, MD (1) · Carlos Rodriguez-Galindo (1) · Claude Sportes, MD (1) · Costantine Albany, MD (1) · Darren Feldman, MD (1) · David Hockenbery, MD (1) · Dean F. Bajorin, MD (1) · Eric J. Small, MD (1) · Ewa Carrier (1) · Gedske Daugaard, MD, DMSc (1)
PMID 15459300, PMID 15999102, PMID 17235042, PMID 17634488, PMID 18974373, PMID 19547919, PMID 21059637, PMID 25001888, PMID 25456363, PMID 37783480, PMID 39167741
U10CA180886 (2), 2005 (1), P30CA008748 (1), P30CA033572 (1), R01CA093891 (1), U10CA021115 (1), U10CA031946 (1), U10CA098543 (1)