13 completed, 4 terminated, 4 unknown, 3 recruiting. 14 Not applicable, 2 Phase 1, 2 Phase 2.
Follow Ehlers-Danlos syndrome type 3: new trials by email Literature Review of Ehlers-Danlos syndrome type 3 trials Research Report on Ehlers-Danlos syndrome type 3
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| Presentation of Young Adults With and Without Joint Hypermobility Hypermobile Ehlers-Danlos Syndrome, Postural Orthostatic Tachycardia Syndrome (POTS) | Enrolling by invitation | Clarkson University | 100 | 2026-09-23 | 2026-10-22 | |
| STABLE Pilates for Hypermobility Pilates, Education - Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS) | Not applicable | Recruiting | Brigham and Women's Hospital | 100 | 2026-07-09 | 2026-08-19 |
| Hamstring Strengthening in Hypermobile Conditions Progressive resistance exercise with an emphasis on eccentric hamstring loading. - Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome | Not applicable | Not yet recruiting | University of Calgary | 20 | 2026-06-01 | 2026-06-04 |
| 3D Printed Orthosis for Wrist Instability for Ehlers-Danlos Syndrome Patient 3D scanned and 3D printed wrist hand orthosis - Ehlers-Danlos Syndrome Hypermobility Type (hEDS) | Completed | ELewis | 2 | 2025-08-21 | 2026-09-14 | |
| Out of State - tAN hEDS Transcutaneous Auricular Neurostimulation - Hypermobile EDS (hEDS) | Not applicable | Completed | Medical University of South Carolina | 30 | 2024-11-27 | 2026-06-01 |
| Identifying the Determinants of Bleeding and Hypermobility in Patients With Heavy Menstrual Bleeding Hypermobile Ehlers-Danlos Syndrome, Heavy Menstrual Bleeding | Terminated | St. Jude Children's Research Hospital | 15 | 2024-05-10 | 2026-01-28 | |
| Hypermobile Ehlers-Danlos Syndrome - Transcutaneous Auricular Neuromodulation Transcutaneous Auricular Neurostimulation - Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder | Not applicable | Completed | Medical University of South Carolina | 25 | 2023-07-05 | 2026-06-01 |
| TMD-specific Physiotherapy in hEDS Patients Individuals With Hypermobile Ehlers-Danlos Syndrome Physiotherapy - Hypermobile Ehlers-Danlos Syndrome | Not applicable | Enrolling by invitation | University Hospital Muenster | 25 | 2023-02-02 | 2025-04-27 |
| Central Sensitization and Physical Activity in Adolescents With HSD/hEDS Submax exercise test on a bicycle ergometer - Joint Hypermobility Syndrome, Hypermobile Ehlers-Danlos Syndrome | Completed | Vastra Gotaland Region | 100 | 2022-11-25 | 2023-11-07 | |
| Characterization of Bleeding Disorders in EDS 20 ml venous blood collection - Ehlers-Danlos Syndrome, EDS | Unknown | University Health Network, Toronto | 45 | 2022-11-01 | 2023-05-09 | |
| Ultrastructural Collagen Markers in Ehlers Danlos Syndromes Skin Biopsy - Ehlers-Danlos Syndrome, Classical Ehlers-Danlos Syndrome | Unknown | University Health Network, Toronto | 20 | 2022-10-31 | 2023-11-28 | |
| Oxytocin for Hypermobile Ehlers-Danlos Syndrome Oxytocin, Placebo - Hypermobile Ehlers-Danlos Syndrome, Pain Assessment | Phase 1 / Phase 2 | Terminated | Baylor College of Medicine | 2 | 2022-05-13 | 2025-08-28 |
| Comprehensive Assessment of Nutrition and Dietary Intervention in Hypermobile Ehlers Danlos Syndrome Dietician advice - Hypermobile Ehlers-Danlos Syndrome, Irritable Bowel Syndrome | Not applicable | Completed | Queen Mary University of London | 50 | 2022-04-07 | 2023-08-07 |
| Lung Volume Perception and Impact of a Cognitive Task on Ventilation in Hypermobile Ehlers-Danlos Syndrome. Hypermobile Ehlers-Danlos Syndrome | Completed | Hakimi Adrien | 38 | 2021-09-02 | 2022-07-22 | |
| Dyspnea in Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorder Usual Care plus Inspiratory Muscle Training (IMT) - Hypermobile EDS (hEDS), Hypermobility Syndrome | Not applicable | Completed | University Health Network, Toronto | 34 | 2021-08-16 | 2025-04-02 |
| Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome Percutaneous vagal nerve stimulation (pVNS) device, Acoustic vagal nerve stimulation (aVNS) treatment - Functional Gastrointestinal Disorders, Hypermobile Ehlers-Danlos Syndrome | Not applicable | Recruiting | Medical College of Wisconsin | 90 | 2021-04-05 | 2026-02-13 |
| Integrative Medicine for Hypermobility Spectrum Disorder and Ehlers-Danlos Syndromes (IMforHSDandEDS) Anti-inflammatory (Mediterranean-style) diet, Behavioral and psychosocial support - Ehlers-Danlos Syndrome, Hypermobile EDS (hEDS) | Not applicable | Completed | National University of Natural Medicine | 20 | 2020-12-23 | 2021-07-15 |
| Online Pilates Exercise for People With Hypermobility Online Pilates exercise - Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder | Not applicable | Completed | Clarkson University | 440 | 2019-09-15 | 2026-06-18 |
| Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry No intervention planned, but all patients get our standart treatment - Autonomic Neuropathy, Ehlers-Danlos Syndrome Hypermobility Type | Recruiting | RWTH Aachen University | 200 | 2019-09-15 | 2025-02-04 |
Showing 20 of 28. Sign in to see all of them.
Ehlers-Danlos Syndrome (11) · Pain (4) · Joint Instability (3) · Motor Activity (3) · Postural Orthostatic Tachycardia Syndrome (3) · Ehlers-Danlos syndrome type 1 (2) · Gastrointestinal Diseases (2) · Joint Dislocations (2) · Constipation (1) · Dyspnea (1) · Ehlers-Danlos Syndrome, Type IV (1) · Fatigue (1) · Irritable Bowel Syndrome (1) · Low Back Pain (1)
Cardiovascular Diseases (11) · Collagen Diseases (11) · Congenital Abnormalities (11) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (11) · Connective Tissue Diseases (11) · Genetic Diseases, Inborn (11) · Hematologic Diseases (11) · Hemic and Lymphatic Diseases (11) · Hemorrhagic Disorders (11) · Hemostatic Disorders (11) · Skin Abnormalities (11) · Skin Diseases (11) · Skin Diseases, Genetic (11) · Skin and Connective Tissue Diseases (11) · Vascular Diseases (11)
Anti-Inflammatory Agents (1) · Diet (1) · Educational Status (1) · Exercise (1) · Exercise Movement Techniques (1) · Glucose (1) · Oxytocin (1) · Physical Therapy Modalities (1) · Prolotherapy (1) · Psychiatric Rehabilitation (1) · Rehabilitation (1) · Therapeutics (1)
University Health Network, Toronto (3) · Clarkson University (2) · Hospices Civils de Lyon (2) · Medical University of South Carolina (2) · Baylor College of Medicine (1) · Brigham and Women's Hospital (1) · ELewis (1) · Hakimi Adrien (1) · Hôpital Raymond Poincaré (1) · Manhattan Pain Medicine, PLLC (1) · Medical College of Wisconsin (1) · Medical University of Warsaw (1) · National University of Natural Medicine (1) · Queen Mary University of London (1) · RWTH Aachen University (1)
United States (11) · France (5) · Canada (4) · Germany (2) · Sweden (2) · Belgium (1) · Poland (1) · United Kingdom (1)
Andrea Maier (1) · Brendan Lee, MD, PhD (1) · Cyrille Bergoin, MD (1) · Dmitry Rozenberg, MD, PhD (1) · Erika S Lewis, PT, EdD (1) · Fransiska Malfait, Prof. Dr. (1) · Helena Romero (1) · Jason Siefferman, MD (1) · Jeffrey Borckardt, PhD (1) · Katja Karrento, MD (1) · Leslie N. Russek (1) · Mari Lundberg, Professor (1) · Mariia Safroshkina, MD (1) · Mark Burish, MD PhD (1)
PMID 36300662, PMID 36437696, PMID 36939815, PMID 37194618, PMID 38353245, PMID 38582758, PMID 40629345, PMID 41737369