3 recruiting. 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Recruiting 3 |
Follow Down Syndrome (DS): new trials by email Literature Review of Down Syndrome (DS) trials Research Report on Down Syndrome (DS)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome Levetiracetam 500mg, Placebo - Down Syndrome, Down Syndrome (DS) | Phase 3 | Recruiting | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 120 | 2025-12-22 | 2026-01-12 |
| Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome Epi-ON corneal cross-linking (CXL) - Down Syndrome (DS), Keratoconus | Phase 3 | Recruiting | Woolfson Eye Institute | 225 | 2025-08-01 | 2026-02-02 |
| The Efficacy of Therapy in Patients With Acute Myeloid Leukemia and Down Syndrome in Russia 4 chemotherapy blocks: Course 1 AIE (cytarabine/idarubicin/etoposide), Course 2 AI (cytarabine/idarubicin), Course 3 HAD (high-dose cytarabine (1g)/daunorubicin), Course 4 HA (high-dose cytarabine). - AML (Acute Myelogenous Leukemia), Down Syndrome (DS) | Phase 3 | Recruiting | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 100 | 2025-07-24 | 2025-11-20 |
Down Syndrome (3) · Alzheimer Disease (1) · Corneal Diseases (1) · Dementia (1) · Epilepsy (1) · Epilepsy, Tonic-Clonic (1) · Keratoconus (1) · Leukemia, Myeloid, Acute (1) · Seizures (1)
Abnormalities, Multiple (3) · Chromosome Disorders (3) · Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Intellectual Disability (3) · Nervous System Diseases (3) · Neurobehavioral Manifestations (3) · Neurologic Manifestations (3) · Brain Diseases (1) · Central Nervous System Diseases (1) · Epilepsy, Generalized (1) · Eye Diseases (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1)
Corneal Cross-Linking (1) · Cytarabine (1) · Daunorubicin (1) · Etoposide (1) · Idarubicin (1) · Levetiracetam (1)
Federal Research Institute of Pediatric Hematology, Oncology and Immunology (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · Woolfson Eye Institute (1)
Russia (1) · Spain (1) · United States (1)