23 completed. 23 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 23 | Completed 23 |
| Phase 2 | 1 | Completed 1 |
Follow Disorders of Sex Development: new trials by email Literature Review of Disorders of Sex Development trials Research Report on Disorders of Sex Development
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Open-Label Extension Study of Setmelanotide Setmelanotide - Obesity Associated With Defects in Leptin-melanocortin Pathway | Phase 3 | Completed | Rhythm Pharmaceuticals, Inc. | 28 | 2024-10-21 | 2026-07-15 |
| Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia Chronocort, Cortef, Placebo - Congenital Adrenal Hyperplasia | Phase 3 | Completed | Neurocrine UK Limited | 55 | 2022-05-24 | 2026-10-02 |
| Long-term Safety Study of Chronocort in the Treatment of Participants With Congenital Adrenal Hyperplasia Chronocort - Congenital Adrenal Hyperplasia | Phase 3 | Completed | Immedica Pharma AB | 76 | 2022-04-01 | 2026-06-18 |
| Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma Therapy Exenatide, Placebo - Craniopharyngiomas, Hypothalamic Obesity | Phase 3 | Completed | University Hospital, Bordeaux | 42 | 2017-01-11 | 2026-05-22 |
| A Study of the Efficacy, Safety and Tolerability of Chronocort in Treating CAH Hydrocortisone - Congenital Adrenal Hyperplasia | Phase 3 | Completed | Neurocrine UK Limited | 91 | 2016-08-18 | 2026-10-02 |
| Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity Exenatide, placebo - Hypothalamic Obesity | Phase 3 | Completed | Seattle Children's Hospital | 42 | 2016-03-01 | 2022-05-05 |
| Comparison of Chronocort® With Standard Glucocorticoid Therapy in Patients With Congenital Adrenal Hyperplasia Chronocort®, standard glucocorticoid therapy - Congenital Adrenal Hyperplasia | Phase 3 | Completed | Neurocrine UK Limited | 122 | 2016-02-22 | 2026-10-02 |
| A Clinical Study to Assess the Efficacy and Safety of DA-3002 DA-3002, Genotropin® - Turner's Syndrome | Phase 3 | Completed | Dong-A ST Co., Ltd. | 58 | 2013-02-01 | 2018-07-26 |
| Effect of a Commonly Used Antibiotic, Doxycycline, in Women With Polycystic Ovarian Syndrome doxycycline, Sugar Pill - Polycystic Ovarian Syndrome (PCOS), Irregular Menstrual Cycles | Phase 3 | Completed | University of Rochester | 10 | 2010-11-01 | 2016-01-13 |
| Flexible Dose, Long-term Safety Study of Asenapine for the Treatment of Schizophrenia in Adolescents (P05897) asenapine - Schizophrenia, Paranoid, Schizophrenia, Disorganized | Phase 3 | Completed | Organon and Co | 204 | 2010-09-28 | 2024-05-22 |
| Fixed Dose Efficacy and Safety Study of Asenapine for the Treatment of Schizophrenia in Adolescents (P05896) asenapine 2.5 mg, asenapine 5.0 mg, placebo - Schizophrenia, Paranoid, Schizophrenia, Disorganized | Phase 3 | Completed | Organon and Co | 306 | 2010-09-28 | 2024-05-21 |
| Androgen for Leydig Cell Proliferation Testosterone undecanoate, Castor Oil - Klinefelter Syndrome, Hypergonadotropic Hypogonadism | Phase 2 / Phase 3 | Completed | University of Roma La Sapienza | 56 | 2009-06-01 | 2018-09-25 |
| An Open-Label, Multi-centre, Phase III Study of Local Tolerability of ZOMACTON 10MG ZOMACTON - Turner's Syndrome | Phase 3 | Completed | Ferring Pharmaceuticals | 27 | 2005-10-01 | 2011-05-20 |
| Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq Somatropin (rDNA origin) - Turner Syndrome, Renal Insufficiency, Chronic | Phase 3 | Completed | Ipsen | 251 | 2004-06-01 | 2019-12-09 |
| Estrogen Treatment (Oral vs. Patches) in Turner Syndrome 17 beta estradiol - Turner Syndrome, Hypogonadism | Phase 3 | Completed | Nemours Children's Clinic | 16 | 2001-01-01 | 2017-11-30 |
| Evaluating Acceptance of New Liquid Somatropin Formulation in Children With Growth Hormone Deficiency somatropin - Growth Hormone Disorder, Growth Hormone Deficiency in Children | Phase 3 | Completed | Novo Nordisk A/S | 168 | 2000-10-23 | 2017-02-27 |
| The Effect of Growth Hormone in Very Young Girls With Turner Syndrome Somatropin - Turner Syndrome | Phase 3 | Completed | Eli Lilly and Company | 100 | 1999-08-01 | 2006-12-04 |
| Induction of Puberty With 17-beta Estradiol in Girls With Turner Syndrome 17-beta estradiol - Genetic Disorder, Turner Syndrome | Phase 3 | Completed | Novo Nordisk A/S | 50 | 1998-07-23 | 2017-02-28 |
| The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women Metformin, Clomiphene citrate, Placebo - Polycystic Ovary Syndrome, Anovulation | Phase 3 | Completed | 59th Medical Wing | 56 | 1997-12-01 | 2006-12-19 |
| Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal Hyperplasia Fludrocortisone, Hydrocortisone, Letrozole - Congenital Adrenal Hyperplasia (CAH) | Phase 3 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 66 | 1995-06-08 | 2025-06-12 |
Showing 20 of 23. Sign in to see all of them.
Turner Syndrome (10) · Adrenal Hyperplasia, Congenital (5) · Dwarfism (3) · Genetic Diseases, Inborn (3) · Sexual Infantilism (3) · Hyperandrogenism (2) · Hypogonadism (2) · Infertility (2) · Obesity (2) · Polycystic Ovary Syndrome (2) · Schizophrenia (2) · Schizophrenia, Disorganized (2) · Schizophrenia, Paranoid (2) · Anovulation (1)
Congenital Abnormalities (23) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (23) · Endocrine System Diseases (23) · Female Urogenital Diseases (23) · Female Urogenital Diseases and Pregnancy Complications (23) · Gonadal Disorders (23) · Male Urogenital Diseases (23) · Urogenital Abnormalities (23) · Urogenital Diseases (23) · Genetic Diseases, Inborn (13) · Gonadal Dysgenesis (13) · Chromosome Disorders (11) · Sex Chromosome Disorders (11) · Sex Chromosome Disorders of Sex Development (11)
Human Growth Hormone (6) · Hydrocortisone (4) · Estradiol (2) · Exenatide (2) · Growth Hormone (2) · asenapine (2) · Androgens (1) · Castor Oil (1) · Clomiphene (1) · Dexamethasone (1) · Doxycycline (1) · Estrogens (1) · Ethinyl Estradiol (1) · Fludrocortisone (1) · Flutamide (1)
Neurocrine UK Limited (3) · Novo Nordisk A/S (3) · Eli Lilly and Company (2) · Organon and Co (2) · 59th Medical Wing (1) · Dong-A ST Co., Ltd. (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Ferring Pharmaceuticals (1) · Immedica Pharma AB (1) · Ipsen (1) · Nemours Children's Clinic (1) · Rhythm Pharmaceuticals, Inc. (1) · Seattle Children's Hospital (1) · Thomas Jefferson University (1) · University Hospital, Bordeaux (1)
United States (12) · France (5) · Czechia (2) · Italy (2) · Japan (2) · Spain (2) · United Kingdom (2) · Belgium (1) · Canada (1) · Denmark (1) · Finland (1) · Germany (1) · Greece (1) · Israel (1) · Netherlands (1)
Andrea Isidori, MD, PhD (1) · Andrea Lenzi, MD (1) · Blandine Gatta-Cherifi, Pr (1) · Byung Kyu Suh, M.D., Ph.D. (1) · Chang Jong Kim, M.D., Ph.D. (1) · Cheol Woo Ko, M.D., Ph.D. (1) · Choong Ho Shin, M.D., Ph.D. (1) · Christian Roth, MD (1) · D Merke (1) · David Meeker, MD (1)
PMID 26091193, PMID 33527139, PMID 15784709, PMID 16757526, PMID 20733274, PMID 21619701, PMID 31532522, PMID 34893062, PMID 38450721, PMID 39672600
2009 (2), 2004 (1)