50 completed, 10 unknown, 4 recruiting, 4 withdrawn. 20 Not applicable, 18 Phase 4, 8 Phase 2, 7 Phase 3, 1 Phase 1.
Follow Anovulation: new trials by email Literature Review of Anovulation trials Research Report on Anovulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Half-dose vs Conventional-dose Cetrorelix in ICSI Cycles Infertility, Infertility, Female | Not yet recruiting | Assiut University | 160 | 2026-09-20 | 2026-09-23 | |
| Ovarian Stromal Stiffness and Ovarian Reserve Parameters Via Transvaginal Shear Wave Elastography Transvaginal Shear Wave Elastography - Ovarian Reserve Markers, Ovarian Function | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | 100 | 2026-08-01 | 2026-08-20 |
| Letrozole Extended vs Traditional Therapy for Ovulation Induction in Women With PCOS (PROLEx-PCOS) Traditional Letrozole Therapy, Extended Letrozole Therapy - PCOS (Polycystic Ovary Syndrome), Infertility | Not applicable | Recruiting | GABRIEL MONTEIRO PINHEIRO | 20 | 2025-09-01 | 2025-11-28 |
| Clomiphene Citrate Alone Versus Clomiphene Plus Metformin as First Line Approach for the Treatment of Anovulation in Infertile Patients With Polycystic Ovary Syndrome Clomiphane citrate + Metformin, clomiphene citrate alone - Polycystic Ovary Syndrome (PCOS), Anovulatory Infertility | Not applicable | Completed | Independent University Hospital, Pakistan | 218 | 2025-01-01 | 2026-10-13 |
| The REgistry of Very Early Estrogen and AnovuLation Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24), REVEAL Questionnaire - Hypothalamic Amenorrhea, Functional, Hypothalamic Amenorrhea | Recruiting | Mayo Clinic | 100000 | 2024-07-01 | 2025-11-21 | |
| Diagnostics of Clinical Hyperandrogenism Assessment of the severity of hirsutism using the visual modified Ferriman-Gallwey scale, Assessment of the severity of endogenetic alopecia using the visual Ludwig Scale - Anovulation, PCOS | Completed | Jagiellonian University | 1330 | 2024-02-29 | 2026-04-02 | |
| Uterine and Endometrial Volume in PCOS and HPOD Two-dimensional and three-dimensional ultrasound of the female reproductive organ - Anovulation, Irregular Menses | Completed | Jagiellonian University | 648 | 2024-01-05 | 2026-03-19 | |
| Quality of Life in Normogonadotropic Anovulation 36-Item Short Form Survey Instrument (SF-36) - Anovulation, Irregular Menses | Completed | Jagiellonian University | 990 | 2023-07-01 | 2026-03-19 | |
| Letrozole vs. Clomiphene Citrate Plus Tamoxifen for Ovulation Induction and Pregnancy Outcomes. Letrozole, Clomiphene Citrate + Tamoxifen - Infertility Drugs, Infertility Involuntary | Phase 3 | Active not recruiting | Sana'a University | 240 | 2023-05-01 | 2026-06-01 |
| Phenotype and Epidemiology of the Polycystic Ovary Syndrome (PCOS) in Colombia (PEP - Colombia) Study. Diagnostic Ultrasound, Venous puncture - Polycystic Ovary Syndrome, Hyperandrogenism | Unknown | Instituto de fertilidad humana, InSer | 626 | 2023-03-04 | 2023-07-03 | |
| Subclinical Hypothyroidism and Normogonadotropic Anovulation Comparison of laboratory test results in women in the 4 study arms - Polycystic Ovary Syndrome, Hypothalamic-Pituitary-Ovarian Axis Dysfunction (Disorder) | Completed | Jagiellonian University | 300 | 2023-03-01 | 2024-02-07 | |
| Sperm Preparation Prior to Intrauterine Insemination Study Zymot Multi sperm separation device, Density gradient centrifugation - Infertility, Infertility Secondary | Not applicable | Recruiting | University of California, San Francisco | 270 | 2023-02-05 | 2026-09-15 |
| Myo-inositol Plus Alpha-lactalbumin in PCOS Myo-inositol-resistant Patients Myo-inositol + folic a. + α-lactalbumin, Myo-inositol + folic a. - PCOS, Myo-inositol-resistance | Not applicable | Completed | Lo.Li.Pharma s.r.l | 50 | 2022-06-13 | 2025-07-11 |
| Feasibility and Safety of Fasting in Fertility Treatment Fasting - Sub Fertility, Female, Fertility Disorders | Not applicable | Completed | Charite University, Berlin, Germany | 34 | 2022-01-10 | 2023-12-29 |
| Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome Vitamin D, Placebo - Polycystic Ovary Syndrome, Anovulation | Not applicable | Recruiting | The University of Hong Kong | 220 | 2021-01-26 | 2024-05-14 |
| LOD vs Gn in Anovulatory PCOs Resistant to First Line Agents Laparoscopic ovarian drilling, Recombinant FSH (rFSH) - Polycystic Ovary Syndrome, Anovulation | Not applicable | Unknown | Assiut University | 200 | 2020-12-01 | 2020-10-14 |
| Inositol Supplementation to Treat PCOS (INSUPP-PCOS) Placebo, Inositol - Polycystic Ovary Syndrome, Anovulation | Phase 2 | Completed | Milton S. Hershey Medical Center | 154 | 2020-01-24 | 2026-01-07 |
| Hormonal Effects of the Oral Gonadotropin Releasing Hormone (GnRH) Antagonist at Different Periods of the Menstrual Cycle Elagolix 200 MG Oral Tablet [Orilissa] - Ovulation; Failure or Lack of | Phase 4 | Unknown | University of Southern California | 12 | 2019-10-01 | 2019-08-19 |
| Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction Salsalate, Placebo - Polycystic Ovary Syndrome | Phase 2 | Completed | University of Illinois at Chicago | 60 | 2018-12-05 | 2025-06-10 |
| Endometrial Thickness and Subendometrial Vascularity in Anovulatory Polycystic Ovarian Syndrome Patients Treated by Metformin Metformin - Polycystic Ovary Syndrome, Anovulatory | Phase 4 | Unknown | Ain Shams Maternity Hospital | 85 | 2018-01-02 | 2018-06-26 |
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Polycystic Ovary Syndrome (42) · Infertility (30) · Hyperandrogenism (9) · Amenorrhea (4) · Infertility, Female (4) · Menstruation Disturbances (4) · Hirsutism (3) · Obesity (3) · Oligomenorrhea (3) · Insulin Resistance (2) · Motor Activity (2) · Weight Loss (2) · Alopecia (1) · Dysmenorrhea (1)
Adnexal Diseases (74) · Female Urogenital Diseases (74) · Female Urogenital Diseases and Pregnancy Complications (74) · Genital Diseases (74) · Genital Diseases, Female (74) · Gonadal Disorders (74) · Ovarian Diseases (74) · Urogenital Diseases (74) · Endocrine System Diseases (73) · Cysts (42) · Neoplasms (42) · Ovarian Cysts (41) · Pathological Conditions, Signs and Symptoms (13) · 46, XX Disorders of Sex Development (9) · Adrenogenital Syndrome (9)
Clomiphene (21) · Metformin (12) · Letrozole (4) · Inositol (3) · follitropin alfa (3) · Blood Specimen Collection (2) · Chorionic Gonadotropin (2) · Folic Acid (2) · Glycoprotein Hormones, alpha Subunit (2) · Medroxyprogesterone Acetate (2) · Anastrozole (1) · Angptl4 protein, mouse (1) · Centrifugation, Density Gradient (1) · Clarithromycin (1) · DA-3801 (1)
University Magna Graecia (9) · Jagiellonian University (4) · Assiut University (3) · Emory University (2) · Ferring Pharmaceuticals (2) · Lo.Li.Pharma s.r.l (2) · Milton S. Hershey Medical Center (2) · National Institute of Environmental Health Sciences (NIEHS) (2) · Sheffield Teaching Hospitals NHS Foundation Trust (2) · University of Illinois at Chicago (2) · 59th Medical Wing (1) · Ain Shams Maternity Hospital (1) · Ain Shams University (1) · Amy E Rothberg (1) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (1)
United States (21) · Italy (10) · Poland (4) · Egypt (3) · United Kingdom (3) · Germany (2) · Turkey (Türkiye) (2) · Brazil (1) · Bulgaria (1) · Canada (1) · China (1) · Colombia (1) · Denmark (1) · France (1) · Hong Kong (1)
Stefano Palomba, MD (8) · Francesco Orio, MD (5) · Achille Tolino, MD (4) · Robert Jach, Prof. (2) · Ahmed M Alaa Eldin (1) · Ahmed M Badawy, Prof (1) · Ahmed N. Fetih, M.D. (1) · Alan S Penzias, MD (1) · Albert Asante, MD, MPH (1) · Amy E Rothberg, MD (1) · Anders N Andersen, Prof. MD (1) · Andreas Michalsen, Prof. Dr. (1) · Anne B Loucks, Ph.D. (1)
PMID 11163814, PMID 11726570, PMID 16368745, PMID 18158291, PMID 18440534, PMID 19095663, PMID 19933994, PMID 2005218, PMID 20435692, PMID 20858697, PMID 21193187, PMID 21606131, PMID 21704212, PMID 22397748, PMID 22500852, PMID 25395741, PMID 26848057, PMID 27336206, PMID 28323948, PMID 28525302, PMID 28854590, PMID 29605405, PMID 29747700, PMID 29889764, PMID 30328739, PMID 30383729, PMID 30590587, PMID 33347618, PMID 34553156, PMID 3543765, PMID 36165742, PMID 36400597, PMID 36708012, PMID 38335228, PMID 38684265, PMID 40929646, PMID 42855686
2009 (1), K12HD001259 (1), M01RR000034 (1), P50HD012303 (1), R01AT009484 (1), R01DK107605 (1), R01HD093748 (1), R56HD089962 (1)