41 completed, 7 terminated, 6 unknown, 5 active not recruiting. 30 Phase 3, 20 Phase 2, 5 Phase 4, 4 Not applicable, 4 Phase 1.
Follow Flutamide: new trials by email Literature Review of Flutamide trials Research Report on Flutamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autonomic and Renal Contributions to Hypertension With ADT Gonadotropin Releasing Hormone Agonists (GNRH), Androgen receptor (AR) inhibitor, Placebo - Androgen Deprivation Therapy, Prostate Cancer | Phase 4 | Recruiting | Virginia Commonwealth University | 50 | 2026-08-01 | 2026-09-30 |
| Contributions to Hypertension With Androgen Deprivation Therapy Gonadotropin Releasing Hormone Agonists (GNRH), Androgen receptor (AR) inhibitor, Placebo - Androgen Deprivation Therapy, Prostate Cancer | Phase 4 | Terminated | University of Colorado, Denver | 10 | 2023-09-20 | 2026-09-02 |
| Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion Micronized progesterone, Placebo, Flutamide - PCOS, Polycystic Ovary Syndrome | Early Phase 1 | Unknown | University of Virginia | 10 | 2022-10-26 | 2023-11-02 |
| Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial Bicalutamide, Buserelin, Darolutamide - Prostate Adenocarcinoma | Phase 3 | Active not recruiting | NRG Oncology | 2050 | 2021-12-06 | 2026-08-17 |
| Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer PET-directed Local Therapy using Surgery, PET-directed Local Therapy using Radiation, Salvage Local Therapy for locally recurrent disease - Prostate Cancer, Oligometastasis | Phase 2 / Phase 3 | Active not recruiting | VA Office of Research and Development | 378 | 2021-07-01 | 2026-10-19 |
| Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial Apalutamide, Bicalutamide, Biospecimen Collection - Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 | Phase 3 | Active not recruiting | NRG Oncology | 2753 | 2021-01-21 | 2026-08-17 |
| Evaluation of Efficacy of Topical Flutamide in the Treatment of Acne Vulgaris Flutamide 1% gel, topical gel without flutamide - Acne Vulgaris Superficial Mixed Comedonal and Inflammatory | Not applicable | Completed | Zagazig University | 50 | 2021-01-13 | 2022-07-28 |
| Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients Leuprorelin, Goserelin, Triptorelin - Prostatic Neoplasms | Phase 4 | Unknown | Wonju Severance Christian Hospital | 164 | 2020-01-23 | 2021-07-29 |
| Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression Flutamide, Placebo - Prostate Cancer | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 25 | 2019-05-10 | 2025-10-16 |
| Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer Abiraterone, Bicalutamide, Degarelix - Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 1273 | 2018-09-24 | 2026-10-08 |
| Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery Bicalutamide, Degarelix, Docetaxel - Stage I Prostate Adenocarcinoma AJCC v7, Stage II Prostate Adenocarcinoma AJCC v7 | Phase 2 / Phase 3 | Active not recruiting | NRG Oncology | 612 | 2017-04-05 | 2026-09-14 |
| Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate Cancer Enzalutamide, Flutamide, Androgen deprivation therapy - Prostate Cancer | Phase 4 | Completed | Astellas Pharma Inc | 206 | 2016-11-02 | 2024-12-09 |
| Androgen Deprivation Therapy or Androgen Deprivation Therapy Plus Definitive Treatment (Radiation or Surgery) Bicalutamide, goserelin acetate, flutamide - Prostate Cancer | Phase 2 | Unknown | Fudan University | 200 | 2015-09-01 | 2020-07-07 |
| Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy. Enzalutamide, Flutamide - Castration-resistant Prostate Cancer | Phase 2 | Completed | Taro Iguchi, MD, PHD | 104 | 2014-12-01 | 2021-09-16 |
| Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women Flutamide, Placebo - Polycystic Ovary Syndrome (PCOS) | Phase 2 | Completed | University of California, Los Angeles | 23 | 2013-04-01 | 2025-01-10 |
| Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer Abiraterone Acetate, Bicalutamide, Degarelix - Prostate Adenocarcinoma, Recurrent Prostate Carcinoma | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 310 | 2013-02-05 | 2026-08-11 |
| Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer GnRH agonist, Anti-androgen, TAK-700 - Prostate Cancer | Phase 3 | Completed | Radiation Therapy Oncology Group | 239 | 2012-05-01 | 2026-03-06 |
| Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer bicalutamide, flutamide, LHRH agonist (antagonist) therapy - Prostate Cancer | Phase 3 | Completed | Radiation Therapy Oncology Group | 1538 | 2009-09-01 | 2026-03-06 |
| Effect of High Testosterone on Sleep-associated Slowing of Follicular Luteinizing Hormone (LH) Frequency in Polycystic Ovary Syndrome Flutamide, Placebo - Polycystic Ovary Syndrome | Phase 1 | Unknown | University of Virginia | 72 | 2009-01-01 | 2023-11-02 |
| Effects of Flutamide on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome Flutamide, Placebo - Polycystic Ovary Syndrome | Not applicable | Terminated | Virginia Commonwealth University | 8 | 2008-07-01 | 2014-09-08 |
Showing 20 of 62. Sign in to see all of them.
Prostatic Neoplasms (48) · Polycystic Ovary Syndrome (6) · Hyperandrogenism (2) · Hypertension (2) · Infertility (2) · Kidney Diseases (2) · Primary Dysautonomias (2) · Adenocarcinoma (1) · Adrenal Hyperplasia, Congenital (1) · Amenorrhea (1) · Anovulation (1) · Carcinoma, Ovarian Epithelial (1) · Hirsutism (1) · Insulin Resistance (1) · Metabolic Syndrome (1)
Radiation Therapy Oncology Group (11) · M.D. Anderson Cancer Center (4) · NCIC Clinical Trials Group (4) · Alliance for Clinical Trials in Oncology (3) · NRG Oncology (3) · Takeda (3) · University of Virginia (3) · National Cancer Institute (NCI) (2) · SWOG Cancer Research Network (2) · University of Washington (2) · Virginia Commonwealth University (2) · Astellas Pharma Inc (1) · Burzynski Research Institute (1) · Dana-Farber Cancer Institute (1) · Eastern Cooperative Oncology Group (1)
United States (42) · Canada (16) · France (3) · China (2) · Israel (2) · Japan (2) · Puerto Rico (2) · United Kingdom (2) · Australia (1) · Belgium (1) · Chile (1) · Colombia (1) · Egypt (1) · Ireland (1) · Italy (1)
Celestia Higano, MD (2) · Christopher Logothetis (2) · Kim N. Chi, MD (2) · Matthew Babcock, PhD (2) · A. O. Sartor, MD (1) · Abhishek Solanki, MD MS (1) · Alan Pollack, MD, PhD (1) · Alvaro A. Martinez, MD, FACR (1) · Andrea De Censi, MD (1) · Andrea Dunaif, MD (1) · Andrew K. Lee, MD (1) · Anthony V D'Amico, M.D. Ph.D. (1) · Anthony V. D'Amico, MD, PhD (1) · Arif Hussain, MD (1) · Bernard M. Dubray, MD, PhD (1)
PMID 38320143, PMID 36596347, PMID 33999161, PMID 12743142, PMID 14581419, PMID 15169799, PMID 15315996, PMID 16145049, PMID 16323171, PMID 16979837, PMID 17011443, PMID 17194907, PMID 17498886, PMID 17531401, PMID 17575222, PMID 17634487, PMID 17689883, PMID 17881290, PMID 18037582, PMID 18212313, PMID 18243498, PMID 18291508, PMID 18314175, PMID 18413638, PMID 18779620, PMID 18990504, PMID 19029421, PMID 19211454, PMID 19395184, PMID 19395186, PMID 19470936, PMID 19516032, PMID 19706804, PMID 19858385, PMID 19864082, PMID 19957321, PMID 19963436, PMID 20797824, PMID 21751904, PMID 22056152, PMID 22498212, PMID 22931259, PMID 23798006, PMID 24693436, PMID 24864213, PMID 24950779, PMID 25242417, PMID 25534388, PMID 25592642, PMID 25691677
U10CA180868 (3), P30CA016672 (2), U10CA031946 (2), I01CX002277 (1), K01HL164978 (1), P30CA015083 (1), P30CA023074 (1), R01DK073411 (1), R01HD102060 (1), R34MH072878 (1), U10CA032102 (1), U10CA180888 (1), U54HD028934 (1)